A5100741579- Healthcare and Venom Research
- Tryptophan and brain disorders
- Dermatology and Skin Diseases
- COVID-19 Clinical Research Studies
- Cancer-related molecular mechanisms research
- Effects of Radiation Exposure
- Metabolomics and Mass Spectrometry Studies
- Liver Disease Diagnosis and Treatment
- Acupuncture Treatment Research Studies
- interferon and immune responses
- Inflammasome and immune disorders
- Stress Responses and Cortisol
- Ubiquitin and proteasome pathways
- RNA modifications and cancer
- Pelvic floor disorders treatments
- Ion Transport and Channel Regulation
- MicroRNA in disease regulation
- Medicinal Plant Pharmacodynamics Research
- Cancer-related Molecular Pathways
- Gastrointestinal motility and disorders
- Parkinson's Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Protein Degradation and Inhibitors
- Flavonoids in Medical Research
Beijing University of Chinese Medicine
2016-2025
Zhejiang University
2025
Southern University of Science and Technology
2024
Capital Medical University
2022-2024
Beijing Tongren Hospital
2022-2024
Xingtai People's Hospital
2024
Hebei Medical University
2024
Merck & Co., Inc., Rahway, NJ, USA (United States)
2023
Shandong University
2022-2023
Decision Sciences (United States)
2022
Hyperglycaemia is associated with an elevated risk of mortality in community-acquired pneumonia, stroke, acute myocardial infarction, trauma and surgery, among other conditions. In this study, we examined the relationship between fasting blood glucose (FBG) 28-day coronavirus disease 2019 (COVID-19) patients not previously diagnosed as having diabetes.We conducted a retrospective study involving all consecutive COVID-19 definitive outcome FBG measurement at admission from 24 January 2020 to...
Abstract Background Coronavirus disease 2019 (COVID-19) has become a public health emergency of global concern. We aimed to explore the risk factors 14-day and 28-day mortality develop model for predicting survival probability among adult hospitalized patients with COVID-19. Methods In this multicenter, retrospective, cohort study, we examined 828 confirmed COVID-19 in Wuhan Union Hospital Central between January 12 February 9, 2020. Among patients, 516 186 consecutive admitted were enrolled...
Non-alcoholic fatty liver disease (NAFLD) has become a major cause of chronic disease. The Chinese herbal medicine (CHM) Dachaihu decoction (DCHD) been proved to treat NAFLD with good efficacy in previous studies. Based on the TCM principle formula formation, we divided DCHD into soothing part, invigorating spleen and dredging intestine part. Marshall officially proposed concept "intestinal-hepatic axis", which systematically explains interactions between liver. We hypothesized that effect...
Salvianolic acid B prevents body weight gain and improves insulin sensitivity in obese mice. The underlying mechanism behind these effects may be associated with the regulation of metabolic endotoxemia, gut microbiota homeostasis LPS/TLR4 pathway.
Mentha haplocalyx has been widely used for its flavoring and medicinal properties as a traditional Chinese medicine with anti-inflammation properties. The present study was designed to investigate the anti-inflammatory effects potential molecular mechanisms of phenolic fraction M. (MHP) constituent linarin in lipopolysaccharide (LPS)-induced RAW264.7 cells. high-performance liquid chromatography coupled linear ion trap-orbitrap mass spectrometry (HPLC-LTQ-Orbitrap MS) analyze chemical...
Background: It remains unclear whether discharged COVID-19 patients have fully recovered from severe complications, including the differences in post-infection metabolomic profiles of with different disease severities. Methods: COVID-19-recovered patients, who had no previous underlying diseases and were Wuhan Union Hospital for 3 months, matched healthy controls (HCs) recruited this prospective cohort study. We examined blood biochemical indicators, cytokines, lung computed tomography...
This study examines the relationships among family resilience, functional exercise adherence, and symptom burden in postoperative breast cancer patients.In this cross-sectional study, participants consisted of 192 women with who had undergone surgery two hospitals Shandong Province, China. Family were measured using 32-item shortened Chinese version Resilience Assessment Scale (FRAS-C), Postoperative Functional Exercise Compliance for Breast Cancer Patients, M. D. Anderson Symptom Inventory...
Study Type – Diagnostic (case series) Level of Evidence 4 What's known on the subject? and What does study add? Pelvic floor muscle training (PFMT) transvaginal electrical stimulation (TES) are two commonly used forms conservative treatment for stress urinary incontinence (SUI). PFMT may build up structural support pelvis, but many SUI patients unable to perform effectively its primary disadvantage is lack long-term patient compliance. TES a passive that produces PFM contraction compliance...
Paeonol (PAE) and glycyrrhizic acid (GLY) are predominate components of 14 blood-entering ones Piantongtang No. 1, which is a traditional Chinese medicine prescription for chronic migraine with minimal side effects. Both paeonol exhibit analgesic, neuroprotective anti-inflammatory properties individually. Our previous research has highlighted their combined effect (PAE + GLY) in ameliorating symptoms. However, there not yet any studies exploring the mechanism action PAE GLY treatment migraine.
Tocotrienols have been shown many biologic functions such as antioxidant, anti-cancer, maintaining fertility and regulating the immune system so on. In this study, after feeding with tocotrienol-rich fraction from palm oil (TRF) for 2 weeks, Balb/c nude mice were inoculated human colon SW620 cancer cell then continued to feed TRF 4 weeks. At termination of experiments, xenografts removed determined expression Wnt-pathways related protein by immunohistochemistry or western blotting. Liver...
Background: Shen-Qi-Jie-Yu-Fang (SJF) is composed of eight Chinese medicinal herbs. It widely used in traditional medicine for treating postpartum depression (PPD). Previous studies have shown that SJF treats PPD through the neuroendocrine mechanism. Aim: To further investigate effect on immune system, including inflammatory response system and CD4 + CD25 regulatory T (T reg ) cells. Materials methods: Sprague Dawley rats were to create an animal model by inducing hormone-simulated pregnancy...
The objective of this study was to evaluate the effect pulsatile flow on cerebral blood (CBF) in infants with use a mild hypothermic cardiopulmonary bypass (CPB). Thirty scheduled for open heart surgery were randomized group (Group P, n = 15) and nonpulsatile NP, 15). In Group perfusion applied during aortic cross-clamping period, whereas used NP. systolic peak velocity (Vs), end diastolic (Vd), mean (Vm), pulsatility index (PI) resistance (RI) middle artery measured by transcranial Doppler...
Da-Bu-Yin-Wan (DBYW) and Qian-Zheng-San (QZS), two classic traditional Chinese medicinal formulas, were clinically employed to treat Parkinson's disease (PD). Our previous studies demonstrated neuroprotective effects of them on mitochondrial function in PD mice induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). The purpose this research was investigate their possible mechanisms the light ATP-sensitive potassium (mitoKATP) channels. effect DBYW QZS dopamine (DA) neurons...
To investigate the effect of Da-Bu-Yin-Wan and Qian-Zheng-San (DBYW QZS) on mitochondrial mass in Parkinson's disease (PD) cell model induced by 1-Methyl-4-phenylpyridinium Ion (MPP+). The SH-SY5Y was selected treated with MPP+. PD intervened DBYW QZS. CCK-8 method used to detect survival rate cells each group. Mitochondria labeled mitoTracker®Red CMXRos probe observed laser scanning confocal microscope, ImageJ software process images measure form factors; Tetramethylrhodamine methyl ester...