- Tryptophan and brain disorders
- Ion-surface interactions and analysis
- Child and Adolescent Psychosocial and Emotional Development
- Child Abuse and Trauma
- Maternal Mental Health During Pregnancy and Postpartum
- Integrated Circuits and Semiconductor Failure Analysis
- Functional Brain Connectivity Studies
- Alzheimer's disease research and treatments
- Laser-Plasma Interactions and Diagnostics
- Fusion materials and technologies
- COVID-19 and Mental Health
- Traditional Chinese Medicine Studies
- Stroke Rehabilitation and Recovery
- Wound Healing and Treatments
- Pulsed Power Technology Applications
- Stress Responses and Cortisol
- Metabolomics and Mass Spectrometry Studies
- Advanced Proteomics Techniques and Applications
- Dementia and Cognitive Impairment Research
- Mental Health Research Topics
- Neuroinflammation and Neurodegeneration Mechanisms
- 3D Printing in Biomedical Research
- Religion, Spirituality, and Psychology
- Healthcare professionals’ stress and burnout
- Treatment of Major Depression
Capital Medical University
2018-2025
Beijing Xuanwu Traditional Chinese Medicine Hospital
2021-2025
Capital Normal University
2024
First Affiliated Hospital of Zhengzhou University
2024
Xuan Wu Hospital of the Capital Medical University
2018-2024
Shanghai Jiao Tong University
2014-2024
Shaanxi University of Science and Technology
2021-2023
Beijing University of Chinese Medicine
2011-2023
State Key Laboratory of Nuclear Physics and Technology
2017-2023
Peking University
2014-2023
The clinical presentation of common symptoms during depressive episodes in bipolar disorder (BD) and major (MDD) poses challenges for accurate diagnosis. Disorder-specific neuroanatomical features may aid the development reliable discrimination between these two conditions. For our sample 16 BD patients, 19 MDD patients 29 healthy volunteers, we adopted vertex-wise cortical based brain imaging techniques to examine thickness surface area, components volume with distinct genetic determinants....
Keloid disease is characterized by hyperproliferation of responsive fibroblasts with vigorously continuous synthesis extracellular matrix (ECM) components. Although the process which keloids develop poorly understood, most theories etiology are referred to fibroblast dysfunction. A central event in dermal repair release growth factors response skin injury, leads dysregulation several crucial pathways that initiate activation keloid (KFs) and promote ECM accumulation. Hence, strategies aimed...
Constructing Z-scheme heterojunction photocatalysts is a prevalent strategy to prolong the lifetime of photoinduced charge carriers without reducing their redox potentials. Nevertheless, these were usually mingled with type-II heterojunction, leading decrease in potentials carriers. Herein, based on absolute electronegativity semiconductors, photocatalyst GaPO4/α-MoC/Ga2O3 was designed and successfully constructed, which formation prevented between GaPO4 Ga2O3. In photocatalyst, conduction...
Abstract Lipid metabolism and oxidative stress are key mechanisms in Alzheimer's disease (AD). The link between plasma lipid metabolites AD patients is poorly understood. This study was to identify markers that distinguish amnestic mild cognitive impairment (aMCI) from NC, reveal potential links stress. We performed non‐targeted analysis of with AD, aMCI, NC using LC–MS/MS. malondialdehyde (MDA), glutathione peroxidase (GSH‐Px), superoxide dismutase (SOD) levels were assessed. found...
This study was designed to investigate the prevalence of religious belief and its relationship with psychiatric symptoms among Chinese adolescents.
This research investigated the effects of three psychological needs (competence, autonomy, and relatedness) self-determination theory (SDT) automation trust on intention users to employ new interaction technology brought by autonomous vehicles (AVs), especially mode virtual image.This study focuses discussion from perspective motivation applied AV technology. With use a structured questionnaire, participants completed self-report measures related these two technologies; total 155 drivers'...
Neuroinflammation plays a significant role in the progression of frontotemporal dementia (FTD). However, association between peripheral inflammatory factors and brain neurodegeneration is poorly understood. We aimed to examine changes markers patients with behavioural variant FTD (bvFTD) explore potential inflammation structure, metabolism, clinical parameters.Thirty-nine bvFTD 40 healthy controls were enrolled underwent assessment plasma factors, positron emission tomography/magnetic...
Objectives COVID-19 survivors suffer from persistent mental distress and impaired quality of life (QOL) after recovery the infection. However, symptom-symptom interaction between these psychological variables remained unexplored. The present study aimed to determine symptom network (depression, anxiety, sleep disturbance, fatigue, post-traumatic stress disorder) their association with QOL among 535 1 year hospital discharge. Methods 9-item Patient Health Questionnaire, 7-item Generalized...
For quantitative proteomics, efficient, robust, and reproducible sample preparation with high throughput is critical yet challenging, especially when large cohorts are involved, as often required by clinical/pharmaceutical studies. We describe a rapid straightforward surfactant cocktail-aided extraction/precipitation/on-pellet digestion (SEPOD) strategy to address this need. Prior organic solvent precipitation on-pellet digestion, SEPOD treats samples cocktail (SC) containing multiple...
// Zhiqiang Li 1 , Yang Sun Miao Qu 2 Hongxing Wan Fang Cai 3 Peng Zhang 4 Department of Oncology, Sanya People’s Hospital, 572000, China Special Care Unit, Pharmacy, Tongji Medical College, Huazhong University Science and Technology, Wuhan 430030, Correspondence to: Zhang, email: tjh_zhangpeng@outlook.com Keywords: breast cancer, chemoresistance, MNK, eIF4E, β-catenin Received: September 09, 2016 Accepted: November 22, Published: December 01, 2016...
Purpose: There is a lack of national studies examining the relationship between insufficient sleep and depression among Chinese adolescents, previous research has not comprehensively considered related factors. This study aimed to investigate prevalence depressive symptoms in adolescents with explore role associated factors using nationally representative sample China. Patients Methods: A pen-and-paper survey was conducted 24147 from November 2019 January 2020. Data on symptoms, maltreatment...
The changes in gut microbiota and plasma metabolites have been proposed to play a key role post stroke depression (PSD), but clinical study based on combined omics is still lack. This aimed investigate the characteristics of patients 3 months after onset acute ischemic (AIS), compare PSD non-PSD groups, explore possible diagnostic biomarkers. Seventy with were included at AIS onset. Plasma fecal samples collected. Gut microbiome was examined using 16S rRNA sequencing, assessed via targeted...
Dementia with Lewy Bodies (DLB) and Alzheimer's disease (AD) are two types of dementia a relatively high incidence, their clinical manifestations easily confused. However, the cognitive impairment characteristics diseases different, results assessment can help diagnosis disease. To explore different Mini-mental State Examination (MMSE) Montreal Cognitive Assessment Scale (MoCA) in DLB AD patients, to potential markers distinguish DLB. This study included 66 patients DLB, 81 AD, 58...