Xin Fang

ORCID: 0000-0002-0218-7310
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About
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Research Areas
  • Peripheral Artery Disease Management
  • Vascular Procedures and Complications
  • Aortic aneurysm repair treatments
  • Cardiovascular Health and Disease Prevention
  • Diagnosis and Treatment of Venous Diseases
  • MRI in cancer diagnosis
  • Renal and Vascular Pathologies
  • Nonlinear Dynamics and Pattern Formation
  • Congenital Heart Disease Studies
  • Neural Networks and Reservoir Computing
  • Aortic Disease and Treatment Approaches
  • Ocular and Laser Science Research
  • Random lasers and scattering media
  • Neural dynamics and brain function
  • Adipokines, Inflammation, and Metabolic Diseases
  • Advanced Optical Sensing Technologies
  • Central Venous Catheters and Hemodialysis
  • Helicobacter pylori-related gastroenterology studies
  • Chaos control and synchronization
  • Pancreatitis Pathology and Treatment
  • Coronary Interventions and Diagnostics
  • Abdominal Trauma and Injuries
  • Pancreatic and Hepatic Oncology Research
  • Adipose Tissue and Metabolism
  • Liver Disease and Transplantation

Hangzhou First People's Hospital
2005-2024

Zhejiang University
2009-2024

Gansu Provincial Center for Disease Control and Prevention
2024

Beijing University of Chinese Medicine
2014-2021

Taiyuan University of Technology
2019-2021

Wuhan Union Hospital
2016

Union Hospital
2015

Qingdao National Laboratory for Marine Science and Technology
2015

University of Chinese Academy of Sciences
2015

Institute of Oceanology
2015

Background/Aims: Obesity has become a major health concern with few effective medications. Cinnamaldehyde (CA) been reported to exhibit anti-diabetic and anti-inflammatory properties. However, whether CA shows anti-obesity activity remains unknown. Therefore, the present study aimed investigate potential effects of on mice fed high-fat diet (HFD) explore possible mechanisms involved. Methods: Male C57BL/6J an HFD for 12 weeks were supplemented (40 mg/kg/day) via gavage additional 8 weeks....

10.1159/000479268 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2017-01-01

Cancer causes a serious health burden on patients worldwide. Chronic low-level inflammation plays key role in tumorigenesis and prognosis. However, the of red blood cell distribution width (RDW)-to-albumin (RA) ratio cancer mortality remains unclear.In this retrospective cohort study, we collected clinical information from Medical Information Mart for Intensive Care III (MIMIC-III) version 1.4 database then calculated RA by dividing RDW albumin concentration. The primary outcome was 30 days...

10.1002/jcla.24423 article EN Journal of Clinical Laboratory Analysis 2022-04-08

Red blood cell distribution width (RDW) is a predictor of adverse outcomes in aortic aneurysms. Recent recommendations suggest that combining RDW with other biomarkers could yield better results. We, therefore, propose evaluating the biomarker vascular aging, albumin to predict risk This study aims explore whether combination can effectively prognosis aneurysm patients.This retrospective cohort was conducted among adults (age >18) aneurysms Medical Information Mart for Intensive Care...

10.2147/ijgm.s328035 article EN cc-by-nc International Journal of General Medicine 2021-10-01

The aim of the study was to describe complex electrophysiological features accessory pathways (APs) in adult Ebstein's anomaly (EA).We performed a retrospective 17 consecutive EA cases with APs who underwent and radiofrequency catheter ablation (RFCA) from November 2011 May 2013. There were total 24 atrioventricular reentrant tachycardias (AVRTs) due 23 APs, including 20 (87.0%) non-decremental conducting, 2 (8.7%) decremental 1 (4.3%) nodofascicular bundle. Six (6/17 = 35.3%) patients had...

10.1093/europace/euu028 article EN EP Europace 2014-03-09

Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin geniposide could inhibit atherosclerosis through Wnt1 dickkopf-related protein-1 (DKK1).The wild-type ApoE-/- mice were treated with baicalin, geniposide, plus daily by gavage for 12 weeks. Blood lipid levels measured an automatic biochemistry analyzer. Aortic atherosclerotic lesion areas...

10.11909/j.issn.1671-5411.2016.10.013 article EN PubMed 2016-10-01

Time-delay signature (TDS) suppression of semiconductor lasers with external optical feedback is necessary to ensure the security chaos-based secure communications. Here we numerically and experimentally demonstrate a technique effectively suppress TDS chaotic using quantum noise. The dynamical complexity are quantified autocorrelation function normalized permutation entropy at delay time, respectively. Quantum noise from quadrature fluctuations vacuum state prepared through balanced...

10.1364/ol.433020 article EN Optics Letters 2021-09-08

Renal arterial stenosis (RAS) often causes renovascular hypertension, which may result in kidney failure and life-threatening consequences. Direct assessment of the hemodynamic severity RAS has yet to be addressed. In this work, we present a computational concept derive new, noninvasive, patient-specific index assess predict potential benefit patient from stenting therapy. The is derived functional relation between translesional pressure indicator (TPI) lumen volume reduction (S) through...

10.1002/cnm.3611 article EN cc-by-nc International Journal for Numerical Methods in Biomedical Engineering 2022-05-05

Diabetes mellitus (DM), a kind of metabolic disease, is increasing over the last four decades in world. The purpose this study was to investigate effect Jiang Tang Xiao Ke (JTXK) granule, naturally occurring ingredient from Chinese herbal medicines, on serum glucose, lipids, and oxidative stress DM rats induced by high-fat diet streptozotocin. JTXK granule 9 g/kg (based crude herb equivalent) pioglitazone 1.5 mg/kg (as positive control for comparison) were orally administrated 4 weeks....

10.1155/2014/475192 article EN cc-by Evidence-based Complementary and Alternative Medicine 2014-01-01

Murine regenerating (mReg) genes have been implicated in preserving islet cell biology. Expanding on our previous work showing that overexpression of mReg2 protects MIN6 insulinoma cells against streptozotocin‐induced apoptosis, we now demonstrate induces glucose‐regulated peptide 78 (GRP78) expression via the Akt–mTORC1 axis and ER stress induced by thapsigargin glucolipotoxicity. Activation mTORC1 activity results from both mReg2‐induced increased mTOR phosphorylation as well Raptor GβL....

10.1016/j.febslet.2014.04.030 article EN FEBS Letters 2014-05-04

This study proposes what we believe to be a novel high-spectral-resolution three-frequency Rayleigh lidar for simultaneously measuring middle atmosphere temperature and wind. The wind could retrieved without assuming an external reference temperature, as typical traditional Doppler lidar. Adopting similar idea used in sodium temperature/wind lidar, this system alternatively emits laser pulses at three frequencies. It receives the corresponding backscattered signals filtered by iodine cell...

10.1364/oe.527608 article EN cc-by Optics Express 2024-06-24

Our aim was to study the therapeutic effects and mechanism of combination hemofiltration (HF) peritoneal dialysis (PD) in treatment severe acute pancreatitis (SAP).Fifty-one cases SAP were randomly divided into HF+PD group (treated group, 36 patients) non-HF+PD (control 15 patients). Both groups treated by same traditional methods. The relief time abdominal pain distension, computed tomographic scores, physiology chronic health enquiry II length stay, cost hospitalization, operability,...

10.1097/mpa.0b013e3181bab38b article EN Pancreas 2009-12-17

This study investigated the 1-year clinical outcomes of directional atherectomy combined with drug-coated balloon (DA + DCB) in femoropopliteal artery disease (FPAD) from real-world experience.A retrospective was conducted patients treated between July 2016 and June 2019 using DA DCB for FPAD. Patients' demographics, comorbidities, characteristics outcomes, angiography duplex ultrasound findings were analyzed. The 6-month primary patency, assisted secondary freedom clinically-driven target...

10.1177/15266028211030527 article EN Journal of Endovascular Therapy 2021-07-12

Vascular disease is the leading cause of morbidity and mortality a major disability for Americans, arterial stenosis its most common form in systemic arteries. Hemodynamic characterization stenosed system plays crucial role diagnosis lesion severity decision-making process revascularization, but it not readily available current clinical measurements. The newly emerged image-based computational hemodynamics (ICHD) technique provides great potential to characterize with fine temporospatial...

10.3390/fluids8070198 article EN cc-by Fluids 2023-06-29

We present an experimental technique that can accurately measure the high-order photon correlations of various light fields based on double Hanbury Brown–Twiss scheme. The system consists four conventional binary response single-photon counting modules which are non-photon-number-resolving detectors. theoretically analyze effects conditions coherent, chaotic thermal, Fock and squeezed vacuum states with considering overall efficiency background noise. In experiment, we determine proper...

10.1088/2040-8986/aba3b6 article EN Journal of Optics 2020-07-07

Renal artery aneurysms (RAAs) are rare and usually asymptomatic, some RAAs can be associated with calcifications, which may lead to misdiagnoses as renal calculi, then mistakenly treated.A 69-year-old female patient was admitted the hospital no discomfort diagnosed a large right calculus. The ultrasound computed tomography urography (CTU) scan suggested calculus in pelvis hydrops of kidney. Therefore, we chose percutaneous nephrolithotomy (PCNL) treat calculus, but calculi were found pelvis....

10.1186/s12882-020-01998-0 article EN cc-by BMC Nephrology 2020-08-10

Evaluating entropy rate of high-dimensional chaos and shot noise from analog raw signals remains elusive important in information security. We experimentally present an accurate assessment for physical process randomness. The generation optical-feedback laser randomness limit are quantified unambiguously discriminated using the growth average permutation value memory time. difference filtered with varying embedding delay time is investigated theoretically. High-resolution maps observed over...

10.1364/oe.380213 article EN cc-by Optics Express 2019-12-27

To determine the effects of ginsenoside rg3 on body weight C57BL/6J obese mice and to investigate its underlying loss mechanisms with a focus white fat browning-related factors. Eight-week-old male were fed high-fat diet for 12 successive weeks construct model. standard chow normal control group. After 8 intervention rg3, food intake, weight, mass, blood sugar, lipid profiles in each group detected. Hematoxylin eosin (HE) staining was used observe histological morphology adipose tissues....

10.1016/j.jtcms.2021.01.009 article EN cc-by-nc-nd Journal of Traditional Chinese Medical Sciences 2021-01-01

Peripheral arterial disease (PAD) presenting with underlying hypertension (HTN) poses a higher risk of bilateral lower limb amputation than PAD patients without HTN. While the role HTN management has received limited attention. We analyzed clinical characteristics in adults and explored factors for to construct nomogram evaluating critical ischemia (CLI) lesion severity.

10.2147/ijgm.s342448 article EN cc-by-nc International Journal of General Medicine 2022-11-01
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