- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Blood Pressure and Hypertension Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Cardiac Arrhythmias and Treatments
- Pulmonary Hypertension Research and Treatments
- Cardiac tumors and thrombi
- Cardiovascular Disease and Adiposity
- Viral Infections and Immunology Research
- Cardiac Imaging and Diagnostics
- Cardiovascular Issues in Pregnancy
- Nutrition and Health in Aging
- Gut microbiota and health
- Sexual function and dysfunction studies
- Cardiovascular Effects of Exercise
- Hormonal and reproductive studies
- Heart Rate Variability and Autonomic Control
- Ultrasound and Hyperthermia Applications
- Histiocytic Disorders and Treatments
- Effects of Radiation Exposure
- Microbial Inactivation Methods
- MRI in cancer diagnosis
- Obstructive Sleep Apnea Research
Commercial Aircraft Corporation of China (China)
2025
St Vincent's Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2006-2024
First Affiliated Hospital of Xiamen University
2019-2024
Fudan University
2024
Xiamen University
2024
Sun Yat-sen University
2022-2024
St Vincent's Hospital Sydney
2021-2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Zhongshan Hospital
2024
Abstract Growing evidences have confirmed the effect of Sacubitril/Valsartan (SV) on antihypertension and cardiac protection in general population. However, there was no prospective study about safety SV resistant hypertension myocardial work hemodialysis patients. In this single‐center, prospective, before‐after study, enrolled patients were endured with for more than 6 months. Participants initially instructed to take 50 mg twice daily, dosage gradually increased up 100 daily. The primary...
Background: Biventricular longitudinal strain has been recently demonstrated to be predictive of poor outcomes in various cardiovascular settings. Therefore, this study sought investigate the prognostic implications biventricular patients with coronavirus disease 2019 (COVID-19). Methods: We enrolled 132 consecutive COVID-19. Left ventricular global from apical four-chamber views (LV GLS 4CH ) and right free wall (RV FWLS) were obtained using two-dimensional speckle-tracking...
Background: RVEF (right ventricular ejection fraction) measured by three-dimensional echocardiography (3DE) has been used in evaluating right (RV) function and can provide useful prognostic information other various cardiovascular diseases. However, the value of 3D-RVEF coronavirus disease 2019 (COVID-19) remains unknown. We aimed to investigate whether predict mortality COVID-19 patients. Methods: A cohort 128 COVID-19-confirmed patients who had undergone were studied. Thirty-one healthy...
Acquired and intrinsic radioresistance remains a major challenge during the treatment of patients with colorectal cancer (CRC). Aberrant cholesterol metabolism precipitates development multiple cancers. Here, we report that exogenous or endogenous enhances CRC cells. The addition protects cells against irradiation both in vitro vivo. Sterol response element-binding protein 1/fatty acid synthase (SREBP1/FASN) signaling is rapidly increased to radiation stimuli, resulting accumulation, cell...
Purpose: To describe the correlative relationship between fundus vascular characteristics and severity of coronary artery stenosis. Patients Methods: A total 1447 patients scheduled for hospitalization at Beijing Anzhen Hospital Union angiography to assess conditions February 2022 December were selected. Of these, 1418 cases ultimately obtained, with 29 excluded due failure complete or photography. Severity stenosis was assessed using Gensini score. Fundus images obtained via non-dilated...
BACKGROUND: ET-26 hydrochloride (ET-26HCl) is a novel etomidate analogue designed to alleviate the adrenocortical suppression caused by while retaining rapid sedative-hypnotic onset and stable hemodynamic features of etomidate. This study compared anesthetic effect, stability, recovery profiles ET-26HCl, etomidate, drug propofol in rats. METHODS: The metabolic half-life ET-26HCl was determined vitro using high performance liquid chromatography analysis samples rat plasma liver homogenates...
Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin geniposide could inhibit atherosclerosis through Wnt1 dickkopf-related protein-1 (DKK1).The wild-type ApoE-/- mice were treated with baicalin, geniposide, plus daily by gavage for 12 weeks. Blood lipid levels measured an automatic biochemistry analyzer. Aortic atherosclerotic lesion areas...
With the mounting number of cancer survivors, complications following treatment become novel conundrums and starve for countermeasures. Intravenous immunoglobulin (IVIg) is a purified preparation immune-deficient autoimmune conditions. Here, we investigated whether IVIg could be employed to fight against radiation injuries explored underlying mechanism. Hematopoietic or gastrointestinal (GI) tract toxicity was induced by total body abdominal local irradiation. High-throughput sequencing...
Objective: To estimate the efficacy of traditional Chinese medicine (Chining decoction, CHIN) for radiation-induced oral mucositis in patients with head and neck cancer. Methods: From May 2014 to December 2015, 70 consecutive were randomly assigned receive CHIN (treatment group) or recombinant human epidermal growth factor (rhEGF) spray (control at a 1:1 ratio. was administered treatment group from first day radiotherapy until completion radiotherapy. Simultaneously, rhEGF control on mucosa...
BACKGROUND:Vincristine (VCR) is a major chemotherapy drug for treatment of childhood acute lymphoblastic leukemia (ALL). Triazole antifungal drugs (AFD) are the main agents prevention/treatment invasive fungal infection (IFI), common complication during ALL. This study investigated adverse reactions (ADRs) between VCR and AFD. MATERIAL AND METHODS:A retrospective was performed on 68 children with ALL (39 boys 29 girls, median age: 5 years) who were treated (a total 136 cases, including both...
Patients with obstructive sleep apnea syndrome (OSAS) showed higher prevalence in cardiovascular diseases due to aberrant hypoxia and oxidative stress. However, not all OSAS patients end up disorders, identification of novel biomarker will be invaluable for differentiating at risk. Here we tested the serum matrix metalloproteinase-9 (MMP-9) levels 47 untreated found that MMP-9 level was positively correlated severity OSAS, which consistent degree duration. Besides, complicated systematic...
This study explored the association between socio-economic status (SES) and mortality among patients hospitalized for heart failure (HF) in China.We used data from China Patient-centred Evaluative Assessment of Cardiac Events-Prospective Heart Failure Study (China PEACE 5p-HF Study), which enrolled primarily HF 52 hospitals 2016 2018. SES was measured using income, employment status, educational attainment, partner status. Individual risk factor (SERF) scores were assigned based on number...
The patterns of patients' cognitive function after hospital discharge for heart failure (HF), their prognostic implication and the predictors new-onset impairment remain unknown. We included 2307 patients (64 ± 14 years, 36.4% female sex) hospitalized HF from a cohort who completed testing before 1 month. Among 1658 with normal cognition discharge, 229 (13.8%) 1429 (86.2%) had at month, respectively. Of 649 impairment, 315 (48.5%) 334 (51.5%) transient persistent Multivariable analyses...