A5101150876- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Dermatology and Skin Diseases
- Asthma and respiratory diseases
- Bone and Joint Diseases
- Liver Disease and Transplantation
- Diabetic Foot Ulcer Assessment and Management
- Rheumatoid Arthritis Research and Therapies
- Tryptophan and brain disorders
- Plant Disease Resistance and Genetics
- Effects of Radiation Exposure
- Orthopedic Infections and Treatments
- Medical Imaging and Analysis
- Hepatitis C virus research
- Hip disorders and treatments
- Healthcare and Venom Research
- Infant Health and Development
- Diabetes and associated disorders
- Pediatric health and respiratory diseases
- Viral gastroenteritis research and epidemiology
- Medicinal Plant Pharmacodynamics Research
- Immune cells in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Traditional Chinese Medicine Studies
- Yeasts and Rust Fungi Studies
Zunyi Medical University
2019-2025
Hubei University of Chinese Medicine
2023
Renji Hospital
2012-2016
Shanghai Institute of Hematology
2015-2016
Shanghai Jiao Tong University
2012-2015
Hubei University
2011
Wuhan City Chinese Medicine Hospital
2007-2011
Chinese PLA General Hospital
2007-2008
Guiyang College of Traditional Chinese Medicine
2007
Objective This study aimed to investigate the interventional effects and potential underlying mechanisms of Xuanfei Pingchuan Decoction on ovalbumin (OVA)-induced allergic asthma (AA) in mice. Methods Liquid chromatography-mass spectrometry/mass spectrometry (LC-MS/MS) was used analyze identify constituents Decoction. An mouse model induced by using OVA combined with aluminum hydroxide. The resistance index (RI) airway analyzed an AniRes2005 animal pulmonary function analyzer. H&E...
The important pathophysiological role of immune dysfunction, especially innate dysfunction in patients with acute-on-chronic liver failure (ACLF), has been investigated recent years, but dysregulation adaptive immunity remains poorly elucidated. aim this study was to (i) determine the CD3(+) T-lymphocyte count and balance between CD4(+) regulatory T (Tregs) conventional cells (Tconv) hepatitis B virus (HBV)-related ACLF patients; (ii) analyse frequencies Tregs subpopulations; (iii) assess...
As immune regulatory and effector cells, monocytes play an important role in the blood-extracorporeal circuit contact-related acute lung injury patients undergoing cardiopulmonary bypass (CPB). However, circulating are phenotypically functionally heterogeneous, so we characterised how immature affect induced by CPB.The identification dynamic changes monocyte subsets were monitored flow cytometry CPB a rat model of CPB. The differentiation migration explored vitro cultures adoptive transfer...
Abstract Background RAF and ERK pathways are known to be activated in human rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS), which play an important role the pathogenesis destruction of RA. Gentisic acid (GA) was a natural product derived from plants, has been reported can attenuate pressure overload‐induced cardiac hypertrophy fibrosis mice through inhibition ERK1/2 pathway. Whether GA inhibit occurrence development RA RAF/ERK signaling pathway not reported. The purpose this...
Objective The aim of this study was to investigate the antioxidant effect and potential mechanism Modified Haoqin Qingdan Decoction on ovalbumin (OVA)-induced allergic asthma (AA) mice. Methods AA model mice induced by OVA combined with aluminum hydroxide. Resistance Index (RI) in airway analyzed AniRes2005 animal pulmonary function analyzer. H&E staining used evaluate pathological changes lung tissue. apoptosis tissue detected TUNEL staining. percentage EOS cells bronchoalveolar lavage...
Jiawei Fengshining (JWFSN) is a new formula originated from Fengshining, classic for the treatment of rheumatoid arthritis (RA). The mechanism JWFSN in RA still unclear. aim this study was to evaluate effect on inflammatory mediator levels serum and TGF-β1/Smad pathway synovium explore underlying mechanisms ameliorate synovial hyperplasia apoptosis inhibition rats with RA.SPF female Wistar were randomly divided into 6 groups: blank control group, model positive drug low-, medium-, high- dose...
Abstract Objective: To retrospectively study the patients with early stage osteonecrosis of femoral head (ONFH) and evaluate clinical efficacy "bone erosion" Pill combined tonifying kidney strengthening bone therapy in treatment this disease explore its mechanism action. Methods: A retrospective was used to collect data who met diagnostic criteria for necrosis Wuhan Hospital Traditional Chinese Medicine from June 2022 2023 (all cases were unilateral ischemic head). These included group (60...
Objective To study apoptosis and antigen presentation changes of monocytes in HBV-related acute-on-chronic liver failure (ACLF) patients under immune dysfunction state.Methods Peripheral blood samples 26 ACLF (ACLF group),20 active chronic hepatitis B (CHB group) 18 healthy individuals (control were collected.The proliferation (Ki67) the expression surface markers including human leukocyte (HLA)-DR B7 molecules (CD86) analyzed by flow cytometry. Results The percentage Annexin V expressed...