A5069539294- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Respiratory viral infections research
- Respiratory Support and Mechanisms
- Plant Reproductive Biology
- Autoimmune Bullous Skin Diseases
- Viral Infections and Vectors
- Skin and Cellular Biology Research
- Vector-borne infectious diseases
- IL-33, ST2, and ILC Pathways
- Pleural and Pulmonary Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Congenital Heart Disease Studies
- Influenza Virus Research Studies
- Asthma and respiratory diseases
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
- Pulmonary Hypertension Research and Treatments
- Viral gastroenteritis research and epidemiology
- Bartonella species infections research
- Mechanical Circulatory Support Devices
Yamaguchi Prefecture Central Hospital
2023-2024
Kanagawa Children's Medical Center
2020-2024
Yamaguchi University
2016-2023
Yamaguchi University Hospital
2022
Congenital diaphragmatic hernia (CDH) is associated with high neonatal mortality. We performed this study to test the hypothesis that left ventricular (LV) and right (RV) volumes assessed by three-dimensional echocardiography may be mortality in CDH.This was a single-center retrospective cohort involving 35 infants CDH. RV LV end-diastolic volume (RVEDV LVEDV, respectively) were measured corrected birth body weight (BBW) on day 1. RVEDV/BBW, LVEDV/BBW, LVEDV/RVEDV compared between CDH...
Abstract We present the case of a 6‐year‐old girl with cat‐scratch disease (CSD), who developed severe pleuritis without lymphadenitis. Bartonella henselae DNA was detected on real‐time polymerase chain reaction (PCR) analysis whole blood. This is first report CSD diagnosed PCR using
Background Epidermolysis bullosa simplex (EBS) is a rare genodermatosis resulting from multiple gene mutations, including KRT5 and KRT14. The clinical expression of the mechanobullous skin fragility disease has not been fully explained by genotype. Case Description An 11-day-old Japanese newborn infant was hospitalized because herpetiform blistering on feet, which expanded systemically after birth. There no evidence virus infection. biopsied lesion showed blister lamina densa without keratin...
Diazoxide, a drug used to treat hyperinsulinemic hypoglycemia (HH), is associated with pulmonary hypertension (PH), as reported by the US Food and Drug Administration. However, no report has detailed association between diazoxide dose PH development. We case of an infant HH, subsequently complicated diazoxide-induced PH. When was introduced, did not appear initially, but it developed during increased dosing. monitored via regular echocardiography examinations. gradually improved tapering...
Pandemic influenza virus A(H1N1)pdm09 infection occurred in healthy children and young adults, but asthmatic patients presented more rapid progression of respiratory distress plastic bronchitis. To investigate the pathogenesis worsening symptoms after infection, we focused on matrix metalloproteinase-9 (MMP-9) tissue inhibitor metalloproteinases-1 (TIMP-1). MMP-9 TIMP-1 levels bronchoalveolar lavage fluid serum from mice with without asthma were evaluated or seasonal A(H1N1) infection....
Abstract Introduction For patients with a congenital diaphragmatic hernia, conventional mechanical ventilation (CMV) and high‐frequency oscillatory (HFOV) are used in initial ventilatory management. HFOV has recently been recommended as rescue therapy; however, we use for management, preoperative challenge test CMV conversion respiratory function testing at the time of conversion. We aimed to compare patient characteristics between conversion‐ HFOV‐preferred treatment groups. Methods...
Abstract Background Congenital diaphragmatic hernia is a deficiency of the fetal diaphragm resulting in herniation abdominal viscera into thoracic cavity. The best method respiratory management congenital unclear, but high frequency oscillatory ventilation often used as initial ventilator mode for severe hernia. When it becomes impossible to maintain pre-ductal saturations, timing successful switching from conventional mechanical remains unclear. Herein, we reported two cases which airway...
Epidermolysis bullosa (EB) is a heterogeneous group of inherited disorders characterized by the blistering skin and mucous membranes. Although molecular basis EB has been significantly elucidated, precise phenotypes lethal types have not completely characterized. Herein, we report severe case with pyloric atresia (PA). The patient was Japanese boy who only had lesions but also various complications such as PA, dysphagia, hypotonia, infectious keratitis corneal ulcer, obstructive uropathy...
Saddle pulmonary thromboembolism (PTE) is defined as a straddling the bifurcation of main artery trunk and it rarely seen in extremely low birth weight infants (ELBWI). PTE critical disease that requires urgent treatment. However, treatment guidelines for ELBWI are not established. We present case 1-day-old preterm infant (gestational age 23 weeks) who showed sudden desaturation hypertension due to saddle PTE. A thrombus was observed artery. The blood flow on left side interrupted, right...
Introduction: Interleukin (IL)-33 and its receptor ST2L play key roles in the IL-33/ST2 signaling pathway. Soluble ST2 (sST2) inhibits proper function of IL-33. sST2 levels are increased patients with several neurological diseases, but infants hypoxic-ischemic encephalopathy (HIE), IL-33 have not been studied. This study aimed to investigate whether serum useful as biomarkers HIE severity prognostic factors for HIE. Methods: Twenty-three 16 controls (gestational age ≥36 weeks ≥1,800 g birth...
小児気管支喘息の発症及び急性増悪においてウイルス感染は重要な要因の一つである.これまでにライノウイルス,respiratory syncytialウイルスなどの感染に関する報告は多く,さらに近年はヒトメタニューモウイルス,2009年に流行したA(H1N1)pdm09およびエンテロウイルスD68による急性増悪に関する報告も見られるが,新型コロナウイルスに関する報告は多くない.