A5073991094- Glutathione Transferases and Polymorphisms
- Thyroid Cancer Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Nutrition, Genetics, and Disease
- Bioinformatics and Genomic Networks
- Cardiovascular Health and Risk Factors
- Thyroid and Parathyroid Surgery
- Global Cancer Incidence and Screening
- Global Public Health Policies and Epidemiology
- Soil erosion and sediment transport
- Healthcare Systems and Public Health
- Insurance, Mortality, Demography, Risk Management
- Ferroptosis and cancer prognosis
- Global Health Care Issues
- Water Resources and Sustainability
- Mining and Resource Management
- Rangeland Management and Livestock Ecology
- Pituitary Gland Disorders and Treatments
- Health Promotion and Cardiovascular Prevention
- Cervical Cancer and HPV Research
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Water Quality and Pollution Assessment
- Water Quality Monitoring and Analysis
Fudan University Shanghai Cancer Center
2023-2025
Shanghai Medical College of Fudan University
2024
Tianjin Centers for Disease Control and Prevention
2020-2024
China Shenhua Energy (China)
2024
Yancheng Institute of Technology
2024
Medullary thyroid cancer (MTC) is a rare malignancy, with 70% to 80% of cases being sporadic (sMTC). Current guidelines recommend total thyroidectomy (TT) for all preoperatively suspicious sMTC, though there has been increasing support reducing the surgical extent in recent years. However, relevant data are limited. This study aimed comprehensively evaluate safety hemithyroidectomy (HT) sMTC. included 797 patients MTC who received curative-intent initial surgery at 19 participating referral...
Background: The current AJCC TNM staging system for medullary thyroid cancer (MTC) is largely adapted from criteria differentiated cancer, which may not fully capture MTC-specific prognostic factors. This study aimed to evaluate the significance of upper mediastinal lymph node metastasis (LNM) and propose corresponding modifications N category improve their applicability MTC. Methods: We conducted a population-based, retrospective enrolling patients with MTC 19 Chinese referral centers....
Objective: To observe the incidence of acute myocardial infarction (AMI) between 1999 and 2013 in Tianjin residents analyze differences on with various age, gender living urban or rural areas. The data might help for targeted prevention strategies among residents. Methods: AMI were obtained based cardiovascular disease surveillance registry established by Centers Disease Control Prevention (CDC). Related information such as permanent residents' population from Municipal Public Security...
Open-pit coal mining inevitably damages the soil and vegetation in areas. Currently, restoration of cold arid open-pit mines Xinjiang, China, is still initial exploratory stage, especially changes nutrients spoil dumps over time. Dynamic remote sensing monitoring areas their correlation are relatively rare. Using Heishan Open Pit as a case, samples were collected during different discharge periods to analyze uncover mechanisms. Based on four Landsat images from 2018 2023, ecological index...
Abstract Purpose: Medullary thyroid carcinoma (MTC) presents a distinct biological context from other cancers due to its specific cellular origin. This heterogeneous and rare tumor has high prevalence of advanced diseases, making it crucial address the limited therapeutic options enhance complex clinical management. Given accessibility methylation information, we construct largest MTC cohort date. Experimental Design: Seventy-eight fresh-frozen samples constituted our cohort. The...
Objective: To assess the trend and factors responsible for increase of life expectancy residents in Tianjin over past two decades. Methods: Abridged Life Table Arriaga's decomposition method was applied to quantify influence age structure leading causes death on from 1999 2018. Results: In 20 years, increased by 4.97 men women 4.11 years 5.86 respectively. The decrease mortality rate 0-year-old group contributed 19.17% expectancy, while aged ≥55 more with cumulative contribution 67.38%....
<p>Supplementary Methods</p>
<div>AbstractPurpose:<p>Medullary thyroid carcinoma (MTC) presents a distinct biological context from other cancers due to its specific cellular origin. This heterogeneous and rare tumor has high prevalence of advanced diseases, making it crucial address the limited therapeutic options enhance complex clinical management. Given accessibility methylation information, we construct largest MTC cohort date.</p>Experimental Design:<p>Seventy-eight fresh-frozen samples...
<p>List of top 30 differentially methylated regions (DMRs) MTC-C relative to the other two subtypes</p>
<p>Classification and prediction effects of methylation-based MTC clustering system</p>
<p>Classification and prediction effects of methylation-based MTC clustering system</p>
<p>Detailed methylation profile of DMR associated with NNAT</p>
<p>List of top 30 differentially methylated regions (DMRs) MTC-C relative to the other two subtypes</p>
<p>Detailed methylation profile of DMR associated with NNAT</p>
<p>Hyperparameter optimization of elastic net mixing parameter (alpha) in the machine learning model</p>
<p>Hyperparameter optimization of elastic net mixing parameter (alpha) in the machine learning model</p>
<p>Detailed patient information of the MTC methylation cohort</p>
<p>Supplementary Methods</p>
<p>Detailed patient information of the MTC methylation cohort</p>
<div>AbstractPurpose:<p>Medullary thyroid carcinoma (MTC) presents a distinct biological context from other cancers due to its specific cellular origin. This heterogeneous and rare tumor has high prevalence of advanced diseases, making it crucial address the limited therapeutic options enhance complex clinical management. Given accessibility methylation information, we construct largest MTC cohort date.</p>Experimental Design:<p>Seventy-eight fresh-frozen samples...
Survival analysis of cancers' incidence data in Tianjin from 2010 to 2016 was conducted provide the basis for formulating and evaluating regional health policies on cancer prevention treatment.
The incidence of lymph node metastasis in papillary thyroid carcinoma (PTC) is common and a significant risk factor for local recurrence; however, its impact on recurrence patterns among low-risk patients remains uncertain. We aimed to elucidate the effect metastatic type. medical records 1209 with stage T1 PTC who underwent unilateral thyroidectomy ipsilateral central dissection were retrospectively analyzed. study first identified factors different types then categorized as high or low...