Ischemic heart disease is the leading cause of morbidity and death worldwide. The survival rate for cardiac arrest can vary widely depending on several factors, including location (survival in-hospital 25% whereas out-of-hospital 10%), promptness medical intervention, availability standard CPR debrillation. Cardiac a sudden unexpected, often encounter in clinic, forensic autopsies diagnosis be challenging. Histopathological identication timing myocardial infarction become important...

Objective: This systematic review and meta-analysis examines the impact of intensive versus standard blood pressure control following post-endovascular therapy in ischemic stroke patients. Methods: We conducted a accordance with PRISMA (Preferred Reporting Items for Systematic Reviews Meta-Analyses) guidelines by searching PubMed, Google Scholar, Cochrane Central databases from inception to December 2023. The outcomes evaluated included symptomatic intracerebral hemorrhage, functional...

Abstract Eupatorium adenophorum leaves cause hepatotoxicity and cholestasis in rats. The hepatotoxicant has been characterized as 9‐oxo‐10,11‐dehydroageraphorone (ODA), a cadinene sesquiterpene. Oral administration of ODA, mixed feed to rats, caused jaundice 24 h. liver the intoxicated animals had focal areas hepatocellular necrosis, proliferation, dilation bile ducts with degenerative changes lining epithelium. There was marked increase conjugated form plasma bilirubin activities enzymes...

To assess the sero–positivity rate of HIV infection among clinically suspected subjects reproductive age group (15–49 years), biological and behavioral characteristics gender specific variation rate, differentials for history blood transfusion or products other organs, needle exposure symptoms morbidity. Study is based on retrospective data calendar year 2005 obtained from Voluntary Counseling Testing Centre (VCTC) (now renamed as ICTC), Department Microbiology, I.M.S., B.H.U., Varanasi....

We investigated the impact of socio-demographic variables on antenatal care (ANC) utilization and low birth weight a child. Data were collected from 300 pregnant females. Only 22.5% females received full (≥4 visits). Our results showed that female’s age at marriage education plays significant role in improving ANC. observed an overall decrease services provided during each visit. ANC visits first trimester risk having baby with weight. Awareness programs educating families about pregnancy...

This study was conducted to determine the frequency of ossicular chain pathology in case CSOM (Tubotympanic type).100 cases type) were admitted E.N.T. department for surgery.Per-operative we found erosion as well tympanosclerosis ossicles.In our long process and lenticular are most susceptible malleo incudal joint more commonly involved by tympanosclerosis.

Background: Apnea of prematurity (AOP) affects preterm neonates. AOP, combined with intermittent hypoxemic (IH) events frequently prolongs the length stay. Caffeine is preferred medication to treat AOP and may help improve IH events. There lack information on safety discharging neonates home caffeine for in literature. Our objective was assess benefits, if any, infants caffeine. Methods: After IRB approval, discharged from neonatal intensive care unit (NICU) were compared those without a...

Objective: Diabetes, a complex metabolic disorder, poses significant challenges during surgery due to its association with chronic hyperglycemia. Surgical stress triggers hormonal changes, impacting glucose homeostasis. With an increasing global prevalence of diabetes, understanding the interplay between surgery, stress, and diabetes becomes crucial for perioperative management.
 Methods: This hospital-based cross-sectional observational study included 222 patients (111 non-diabetic 111...

We present a case report of fatal mesenteric injury resulting from crushed wine bottle following near hanging incident. The deceased, 23 -year-old male, was found rope in his residence after consuming considerable amount alcohol. Upon investigation, it revealed that the individual had fallen position, leading to he holding being against abdomen. blunt force trauma shattered caused extensive injury, hemorrhagic shock and subsequent death. This underscores potential for severe unexpected...

Mephentermine, a stimulant used to maintain blood pressure in hypotensive states, is also drug misused for performance enhancement due its central nervous system effects1. Here are four cases highlighting misuse: which patient presented with insomnia and irritability experienced palpitation, headaches, hypertension, depressive symptoms after using mephentermine year boost work performance. Whenever he tried discontinue or reduce the dose, developed withdrawal like fatigue, weakness,...

Moringa oleifera, commonly known as the horseradish tree or drumstick tree, is a perennial tropical plant extensively recognized for its nutritional and medicinal properties. Known by various regional names such kelor, marango, mlonge, sajna, M. oleifera has been utilized in traditional folk medicine South Asia Africa centuries. It employed to treat ailments like helminthiasis, paralysis, sores, skin infections, other health conditions, including malnourishment, diabetes, anemia, high blood...

Mitochondria are referred to as the energy centers of cells, and mitochondrial DNA known alter respiratory chain, which reduces cellular causes ion-channel malfunction neuronal cell death. As majority cells contain mitochondria, these disorders involve multiple systems. Since requirements different tissues vary, their vulnerability dysfunction also varies in terms threshold. This appear clinically a variety ways with significant phenotypic overlap. The genotypic definitions some specific...

Left ventricle (LV) diastolic dysfunction is often present in patients with significant coronary artery disease (CAD), even the absence of regional or global LV systolic dysfunction. It has been suggested that abnormalities function may actually precede dysfunction, and therefore, serve as an early sensitive marker ischemia. This study aims to find improvement after percutaneous intervention (PCI) stable unstable angina.In this single-center hospital-based study, we enrolled 309 either CAD...

We present a case of monozygotic identical twins presenting with coronary artery disease (CAD), there were striking similarities in the symptoms, anatomy, and lesions.

<p class="abstract">Osteoarthritis is the most common musculoskeletal condition world over that causes significant health, economic, and societal burdens. Till date, no therapeutic approaches have been able to stop or delay progression of osteoarthritis satisfactorily. Structural clinical features disease are characterized by a high inter-patient variability. This heterogeneity believed be major factor associated with complexity on-going difficulty identify single therapy for all...

Background: Prenatal caffeine adversely affects learning and memory in adult offspring, whereas its administration to adolescent humans improves consolidation of long-term memory. The effects postnatal on are not known. Our objective was assess spatial mice after therapy newborn mice. Methods: Mice pups randomized receive (20 mg/kg per day) or saline intraperitoneally for 10 days birth. Water maze test performed at 14 weeks age. had 60 seconds training 3 consecutive find the platform. A...

Quadripolar left ventricular (LV) leads in cardiac resynchronization therapy (CRT) offer multi-vector pacing with different configurations and hence enabling LV at most suitable site better lead stability. We aim to compare the outcomes between quadripolar bipolar patients receiving CRT. In this prospective, non-randomized, single-center observational study, we enrolled 93 CRT (BiP) (n = 31) (Quad) 62) August 2016 2019. Patients were followed for six months, compared respect response...

The aim of the study was to compare, Modified Frailty Index (mFI), EAARN (LVEF <22%, Atrial Fibrillation, Age ≥70 years, Renal function (eGFR <60 mL/min/1.73m2), NYHA class IV), and ScREEN (female Sex, ≥60 LVEF ≥25%, ECG (QRS duration ≥150 ms) ≤III) score for predicting cardiac resynchronization therapy (CRT) response all-cause mortality.In this prospective, non-randomized, single-center, observational we enrolled 93 patients receiving CRT from August 2016 2019. Pre-implant scores were...