Development of rapid and multiplexed diagnostic tools is a top priority to address the current epidemic problem sexually transmitted diseases. Here we introduce novel nanoplasmonic biosensor for simultaneous detection two most common bacterial infections: Chlamydia trachomatis Neisseria gonorrhoeae. Our plasmonic microarray composed gold nanohole sensor arrays that exhibit extraordinary optical transmission (EOT), providing highly sensitive analysis in label-free configuration. The...

This paper presents a methodology for the diagnosis of HVDC systems based on partial discharge analysis. In particular, characteristics phenomena from different test objects are highlighted, with aim providing tools enabling automatic identification type PD, as well noise and disturbance rejection, on-line and/or off-line PD testing equipments. The results show that, using fuzzy system higher-order moments magnitude inter-time distributions, corona can be identified easily, whereas it is...

This paper deals with the analysis of partial discharge characteristics silicone rubber insulators, aim to develop a better diagnostic tool identify pollution severity outdoor insulators. In this work, laboratory-based performance tests are carried out on insulators under ac voltage at different levels and relative humidity conditions, using sodium chloride as contaminant. Partial (PD) is acquired through an innovative PD detection system which able collect waveforms beside patterns. Time...

We describe an integrated biosensor capable of sensing multiple molecular targets using both cyclic voltammetry (CV) and chronoamperometry (CA). In particular, we present our custom IC to realize voltage control current readout the biosensors. A mixed-signal circuit block generates sub-Hertz triangular waveform for biosensors by means a direct-digital-synthesizer CV. pulse-width converter is realized output data CA measurement. The fabricated in 0.18 μm technology. It consumes 220 μW from...

This paper represents the extended version of conference "Developing highly-integrated subcutaneous biochips for remote monitoring human metabolism" presented at IEEE Sensors Conference 2012, and presents data on assembly, packaging short term in vitro vivo biocompatibility evaluation a fully implantable biosensor array. The device was realized integrating three building blocks: 1) multielectrode platform; 2) an inductive coil; 3) integrated circuit. entire system measures 2.2 mm × 15 mm....

The paper presents that partial discharge detection is an effective tool to prevent premature breakdown of electrical equipment fed by power electronics. it recommended be used as a quality control measure in the factory and online diagnostic procedure service.

Robust and reliable measurements in electrochemical biosensing of molecules are crucial for personalized medicine. Electrochemical sensors based on cytochrome P450 can detect the large majority drugs commonly used pharmacological treatments. The same different substrates; each them changes response enzyme a specific manner. Our system exploits measure electrical potential to identify drug type, while current decode concentration. Since affected by pH temperature, since variations occur...

Abstract Metal foams are cellular structure materials that present open cells, randomly oriented and mostly homogeneous in size shape. Cellular materials, particularly open-cell metal foams, have been proposed as possible substitutes for traditional finned surfaces electronics cooling applications. This article presents the heat transfer pressure drops measurements obtained during air flow through an aluminum foam, which has 40 pores per inch with 0.63 mm pore diameter. The specimen inserted...

Biosensing for chronic pathologies requires the simultaneous monitoring of different parameters such as drug concentrations, inflammation status, temperature and pH. In this paper we discuss design, fabrication test a sensor array hosting five biosensor platforms, pH electrode sensor. Different reproducible nano-bio-functionalization can be obtained with high spatial resolution via selective electrodeposition chitosan/MWCNT/enzyme solutions at various electrodes. The array, completely...

We report the first selective growth of nanographite petals and various carbon nanomaterials onto a multipanel electrochemical platform. Different types can be obtained by fine-tuning parameters chemical vapor deposition (CVD) process. First, absolute novelty is catalytic CVD different only on working electrodes A second at complementary metal-oxide-semiconductor compatible temperatures. These novel have been incorporated in sensors which performance characteristics improve with content...

An amperometric biosensor for adenosine 5 -triphosphate (ATP) was developed applying a competitive assay of two glucose converting enzymes: oxidase (GOD) and hexokinase (HEX). Competition between GOD HEX in presence ATP, lead to decrease the current coming from hydrogen peroxide generated by GOD, allows ATP detection. The realized on commercial screen-printed electrodes modified with carbon nanotubes (CNTs). Confinement CNTs polycarbonate membrane, Chitosan Nafion polymers investigated as...

A novel system for remote monitoring of metabolism in an animal model is proposed this paper. The obtained by integrating bio-nano-sensors to detect single-metabolites, electrochemical front-end made with off-the-shelf components, a radio frequency communication sub-system, and antenna new design. has been calibrated tested continuous four different metabolites: glucose, lactate, glutamate, adenosine triphosphate. Tests using models (mice) have conducted investigate tissue inflammation...

Personalized therapy requires accurate and frequent monitoring of drugs metabolic response in living organisms during drug treatments. In case high risk side effects, e.g. therapies with interfering anti-cancer molecules cocktails, direct the patient's metabolism is essential as pathways efficacy highly variable on a patient-by-patient basis. Moreover, pharmacological treatments are often based cocktails different drugs. Currently, there no fully mature biochip systems to monitor multi-panel...

Investigations carried out on artificial defects are fundamental for understanding partial discharge (PD) behavior in electrical apparatus and establishing expert system databases. In this paper, tests (realized both the lab real transformers) paper/oil insulation discusses. particular, emphasis is given to bubbles (in free oil or between paper layers) PD due floating metal objects, as other sources have been discussed previous works. order provide a thorough picture of phenomena systems,...

A highly integrated system for remote monitoring of several human metabolites is proposed. It obtained by integrating components, such as: bio-probes, carbon nanotubes, micro-fabricated gold-electrodes, temperature and pH sensors, extremely small CMOS IC multilayer coil powering data acquisition transmission. The entire has final sizes only 2.2 mm in width thick it long 1.5 cm. In this paper, results on sensors micro-fabrication, sensing tests, design, power transmission are presented. These...

Label-free DNA detection plays a crucial role in developing point-of-care biochips. Capacitance is promising technology for label-free detection. However, data published literature often show evident time drift, large standard deviation, scattered points, and poor reproducibility. To address these problems, mercapto-hexanol or similar alkanethiols are usually considered as blocking agents. The aim of the present paper to investigate new agents further improve probe surfaces. Data from AFM,...