Aditi Srivastava

ORCID: 0000-0003-3141-7311
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Research Areas
  • Nematode management and characterization studies
  • Phytochemicals and Medicinal Plants
  • Diverse Scientific Research Studies
  • Computational Drug Discovery Methods
  • Natural Antidiabetic Agents Studies
  • Peanut Plant Research Studies
  • Toxin Mechanisms and Immunotoxins
  • SARS-CoV-2 and COVID-19 Research
  • Crop Yield and Soil Fertility
  • Rice Cultivation and Yield Improvement
  • Genetics and Plant Breeding
  • Nigella sativa pharmacological applications
  • Reproductive Physiology in Livestock
  • Transgenic Plants and Applications
  • Soybean genetics and cultivation
  • Parasite Biology and Host Interactions
  • Rabbits: Nutrition, Reproduction, Health
  • Cassava research and cyanide
  • Urinary and Genital Oncology Studies
  • Phytochemicals and Antioxidant Activities
  • Essential Oils and Antimicrobial Activity
  • Genetic and Environmental Crop Studies
  • Agronomic Practices and Intercropping Systems
  • Vitamin C and Antioxidants Research
  • Veterinary Medicine and Surgery

Era's Lucknow Medical College and Hospital
2012-2025

Indian Agricultural Research Institute
2010

Jawaharlal Nehru Medical College Hospital
1993

Aligarh Muslim University
1993

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel etiological agent of disease 2019 (COVID-19). Nigella sativa, commonly known as black seed or cumin, has been historical and traditional plant since thousands years. Based on their therapeutic efficacy, the chief components terpenoids flavonoids were selected from N. sativa seeds oil. This study was designed to check antiviral efficacy main phytoconstituents against five potential targets SARS-CoV-2 using in silico...

10.1080/07391102.2020.1852117 article EN Journal of Biomolecular Structure and Dynamics 2020-12-08

Abstract Background Phoenix dactylifera L. has a diverse set of pharmacological properties due to its distinct phytochemical profile. The purpose this study was investigate the anticancer potential seed extract (PDSE) in human breast cancer MDA-MB-231 and MCF-7 cells, as well liver HepG2 efficacy triple-negative followed by silico validation molecular interaction between active components PDSE caspase-3, an apoptosis executioner protein . Methods In study, cell lines were cultured...

10.1186/s12906-022-03533-0 article EN cc-by BMC Complementary Medicine and Therapies 2022-03-15

Fine needle aspiration (FNA) is a quick, minimally invasive procedure for evaluation of breast tumors. The Scarff-Bloom-Richardson (SBR) grade on histological sections well-established tool to guide selection adjuvant systemic therapy. Grade possible cytology smears avoid and minimize the morbidity associated with overtreatment lower tumors.The aim was test hypothesis whether FNA from peripheral portion lesion representative histopathology as compared central portion.Fine-needle aspirates...

10.4103/1742-6413.92550 article EN CytoJournal 2012-01-31

Coronaviruses are etiological agents of extreme human and animal infection resulting in abnormalities primarily the respiratory tract. Presently, there is no defined COVID-19 intervention clinical trials prospective therapeutic still nascent stage. Withania somnifera (L.) Dunal (WS), an important medicinal plant Ayurveda. The present study aimed to evaluate antiviral potential selected WS phytoconstituents against novel SARS-CoV-2 target proteins ACE2 receptor using silico methods. Most...

10.1080/07391102.2020.1835725 article EN Journal of Biomolecular Structure and Dynamics 2020-11-27

SARS-CoV-2 has been responsible for causing 6,218,308 deaths globally till date and garnered worldwide attention. The lack of effective preventive therapeutic drugs against further worsened the scenario bolstered research in area. N-terminal C-terminal RNA binding domains (NTD CTD) nucleocapsid protein represent attractive drug targets. Naturally occurring compounds are an excellent source novel candidates due to their structural diversity safety. Ten major bioactive were identified...

10.1111/jfbc.14262 article EN Journal of Food Biochemistry 2022-07-07

A sudden outbreak of a novel coronavirus SARS-CoV-2 in 2019 has now emerged as pandemic threatening to efface the existence mankind. In absence any valid and appropriate vaccines combat this newly evolved agent, there is need resource molecules for treatment prophylaxis. To effect, flavonol morin which found fruits, vegetables various medicinal herbs been evaluated its antiviral potential present study. PASS analysis versus reference drugs baricitinib, remdesivir hydroxychloroquine revealed...

10.1080/07391102.2021.1871863 article EN Journal of Biomolecular Structure and Dynamics 2021-02-01

Therapeutic drugs based on natural products for the treatment of SARS-CoV-2 are currently unavailable. This study was conducted to develop an anti-SARS-CoV-2 herbal medicine face urgent need COVID-19 treatment. The bioactive components from ethanolic extract Moringa oleifera fruits (MOFs) were determined by gas chromatography-mass spectroscopy (GC-MS). Molecular-docking analyses elucidated binding effects identified phytocomponents against spike glycoprotein (PDB ID: 6VYB) and human ACE2...

10.1111/jfbc.14062 article EN Journal of Food Biochemistry 2022-01-19

Vaginal fibroids rarely exist as a primary vaginal tumor. Approximately 300 cases have been reported in the literature. Here we are reporting rare case of giant fibromyoma. It was diagnosed cervical fibroid polyp preoperatively but found to be fibromyoma peroperatively.

10.5582/irdr.2015.01037 article EN Intractable & Rare Diseases Research 2015-01-01

There is currently a dearth of specific therapies to treat respiratory infections caused by the three related species coronaviruses viz. SARS-CoV-2, SARS-CoV and MERS-CoV. Prevention from disease safest most convenient alternative available. The present study aimed evaluate preventive therapeutic effect fifteen phytoconstituents medicinal plants Ayurveda against in silico screening. All exhibited rapid GI absorption bioavailability them had no toxicity versus reference drug chloroquine. BAS...

10.1080/07391102.2021.1932601 article EN Journal of Biomolecular Structure and Dynamics 2021-07-09
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