A5101962773- Phytochemicals and Medicinal Plants
- Mitochondrial Function and Pathology
- Drug-Induced Hepatotoxicity and Protection
- Liver Disease Diagnosis and Treatment
- Heavy Metal Exposure and Toxicity
- Hepatitis B Virus Studies
- Diverse Scientific Research Studies
- Computational Drug Discovery Methods
- Advanced Glycation End Products research
- Essential Oils and Antimicrobial Activity
- Mosquito-borne diseases and control
- Metabolism and Genetic Disorders
- bioluminescence and chemiluminescence research
- Biochemical effects in animals
- Viral gastroenteritis research and epidemiology
- Natural Compound Pharmacology Studies
- Viral Infections and Vectors
- Pharmacological Effects of Medicinal Plants
- Curcumin's Biomedical Applications
- Silymarin and Mushroom Poisoning
- Photodynamic Therapy Research Studies
- Piperaceae Chemical and Biological Studies
- SARS-CoV-2 and COVID-19 Research
- Ion Channels and Receptors
- Lipid metabolism and biosynthesis
University of Lucknow
2013-2024
Era's Lucknow Medical College and Hospital
2022
Integral University
2016-2021
Institute of Medical Sciences
2016-2021
Dr. Ram Manohar Lohia Avadh University
2002
Indian Institute of Toxicology Research
1991-1996
Coronaviruses are etiological agents of extreme human and animal infection resulting in abnormalities primarily the respiratory tract. Presently, there is no defined COVID-19 intervention clinical trials prospective therapeutic still nascent stage. Withania somnifera (L.) Dunal (WS), an important medicinal plant Ayurveda. The present study aimed to evaluate antiviral potential selected WS phytoconstituents against novel SARS-CoV-2 target proteins ACE2 receptor using silico methods. Most...
SARS-CoV-2 has been responsible for causing 6,218,308 deaths globally till date and garnered worldwide attention. The lack of effective preventive therapeutic drugs against further worsened the scenario bolstered research in area. N-terminal C-terminal RNA binding domains (NTD CTD) nucleocapsid protein represent attractive drug targets. Naturally occurring compounds are an excellent source novel candidates due to their structural diversity safety. Ten major bioactive were identified...
Objectives: The present study aimed to assess the validity of Indian Diabetes Risk Score (IDRS) and its association with body mass index (BMI) glycosylated hemoglobin (HbA1c) for screening diabetes obesity. Methodology: A cross-sectional was designed, samples were randomly enrolled from Lucknow adjoining areas. Totally, 405 subjects included in study. We used risk factors (age, waist circumference, physical activity, family history diabetes) abdominal obesity (AO) BMI general HbA1c...
There is currently a dearth of specific therapies to treat respiratory infections caused by the three related species coronaviruses viz. SARS-CoV-2, SARS-CoV and MERS-CoV. Prevention from disease safest most convenient alternative available. The present study aimed evaluate preventive therapeutic effect fifteen phytoconstituents medicinal plants Ayurveda against in silico screening. All exhibited rapid GI absorption bioavailability them had no toxicity versus reference drug chloroquine. BAS...
Introduction Diabetes is one of the most challenging non-communicable disease in current century worldwide. T2DM, represents 90–95% total diabetes cases, ranging from predominantly insulin resistance, deficiency to secretory defect1. 422 million people are affected wo
Photosensitization reaction of drugs leading to the formation reactive oxygen species under ultraviolet radiation (UVR) can cause tissue injury, resulting in damage various cellular macromolecules. The aim this study was determine singlet generation potential some commonly used antibiotics so that due precautions be exercised minimize their photosensitizing action and oxidative stress potential. selected were examined for ability produce (1O2) artificial UVA (320–400 nm). Singlet screened is...
Background: Enteric fever is a major public health problem with significant morbidity and mortality in developing countries. Although, isolation of causative organism from blood the standard laboratory method, but due to frequent use self-medication by patients, its long turnaround time, it seldom used, enteric usually diagnosed using serological methods. Widal tube agglutination test which now days replaced slide convenience rapidity. The present study was done comparatively evaluate...
Milk, a cornerstone of neonatal nutrition and human health, harbors various components with antioxidant capabilities, including oligosaccharides. In this study, we explored the potential acetylated milk oligosaccharides (A-MOs) deacetylated (D-MOs) sourced from Rathi cow through assays, focus on their comparative efficacy. Concurrently, evaluated activity Ascorbic Acid (AA) for comparison. Results revealed significant dynamics within profiles A-MOs D-MOs. demonstrated concentration-dependent...
Phytotherapy employs phytoconstituents/phytomedicines derived from plants for treating and preventing illnesses.