For intensive care physicians, burns are a frequent and challenging patient complication. Specialist facilities prioritise stabilisation, infection prevention, functional rehabilitation to the greatest extent possible. Researchers have been focusing on for decades, thanks their efforts, mortality rate burn patients, especially young patients those with moderate burns, has steadily declining. However, intensivist often faces challenges that make it hard provide stabilise patients. There may...

SARS-CoV-2 infection in children accounts for about 1–8% of cases world-wide, most them asymptomatic or mildly symptomatic. Neonatal is rare and usually asymptomatic. Since April 2020, severe manifestations were seen Europe North America, presenting as Kawasaki disease-like illness involving multiple organs. The Centers Disease Control Prevention termed this multisystem inflammatory syndrome (MIS-C) developed a case definition. World Health Organization similar definition with slight...

Performance evaluation of wastewater treatment plants (WWTPs) with special reference to toxicity reduction using Daphnia magna straus as test organism is very important study the likely adverse effects thetreated on aquatic ecosystem receiving waters and detect common environmentally realistic concentrations pollutants at different concentration levels discriminatory ability distinguish degree toxic specificity compounds target organisms. This can be considered asuseful analytical tool for...

Objectives: The present study aimed to assess the validity of Indian Diabetes Risk Score (IDRS) and its association with body mass index (BMI) glycosylated hemoglobin (HbA1c) for screening diabetes obesity. Methodology: A cross-sectional was designed, samples were randomly enrolled from Lucknow adjoining areas. Totally, 405 subjects included in study. We used risk factors (age, waist circumference, physical activity, family history diabetes) abdominal obesity (AO) BMI general HbA1c...

Background and Aims: The appropriate length of esophageal myotomy in peroral endoscopic (POEM) for achalasia cardia remains unclear. This study aimed to compare the outcome short (≤3 cm) long (≥6 patients with type I II cardia. Methods: single-blinded, randomized controlled noninferiority trial was conducted at a tertiary center between July 2021 December 2021. Patients types were into groups. primary clinical success (Eckardt score ≤3) 1 year after procedure. secondary outcomes included...

A LC-MS/MS method for plasma topiramate analysis is delineated involving least number of healthy volunteers. Topiramate and amlodipine internal standard (IS) were extracted by simple centrifuge-coupled solid-phase extraction reverse-phase chromatographic separation was performed on an Ascentis C(18) column. Turbo-spray negative-ion mode multiple-reaction monitoring selected mass pair detection at m/z 338.3 --> 78.0 407.3 295.5 analyte IS respectively. The showed a dynamic linearity range...

Context: Herpes viruses cause threatening infections in humans and stand second as causative agents for most human viral diseases, after influenza cold viruses. Objective: A novel multiparticulate delivery system acyclovir (ACV), based on ion-exchange resin, was developed to achieve a gastro-mucoadhesive effect order effectively combat the herpes simplex virus. Materials methods: combination of ACV cholestyramine resin optimized further entrapped within sodium alginate Carbopol microbeads....

Scrub typhus, a mite-borne zoonotic disease, is endemic in several parts of India. It may cause multisystemic disease involving lungs, heart, spleen, liver, hematological system, and nervous system. Neurological involvement include meningoencephalitis, cerebellitis, cranial nerve palsies, plexopathy, transverse myelitis, muscle dysfunction, neuroleptic malignant syndrome, parkinsonian Guillain-Barre syndrome. Here, we report rare patient scrub who developed meningoencephalitis followed by...

Calotropis procera is a large shrub which consists many medicinal properties, used in treatment of snake bite, sinus fistula, rheumatism, mumps, burn injuries, inflammation and jaundice traditionally. All the parts were utilized diseases out leaves roots investigated for its toxicity profile that showed dose dependent toxicity. Toxicity flowers was not previous studies. The aim this study to explore acute subacute ethanolic extract safe use traditional medicine. In toxicity, total 20 female...

The present investigation was carried out in a holistic mode to study the interactions among integrated farming system (IFS) components and develop design sustainable IFS model which is technologically sound, economically viable, environmentally benign, socially acceptable for middle Indo-Gangetic Plains. For efficient utilization of farm resources enhance income per unit area land, 10 models have been developed at farmers’ fields Patna, Nalanda, Vaishali districts Bihar, India, during...

The pharmacokinetic parameters of a drug plays very essential role in determining the therapeutic success an experimental compound, so it is one aspects discovery which are to be determined early phases. studies further help team optimize their vivo and safety bioassays.Low solubility, low absorbency, chemical instability can seriously affect bioassay results. Today lot computational software available use algorithms calculate selected compounds hence may move direction where chances getting...

Introduction: Competency-based Medical Education (CBME) has been implemented in India for undergraduate medical students since 2019. Understanding faculty perceptions regarding CBME will help identify barriers and suggestions its better implementation. However, there have limited studies conducted on this aspect Northeast India. Aim: To examine the perception of teaching faculties at Zoram College Mizoram, India, CBME. Additionally, it aims to improved implementation college through Focus...

Aim: -To find the prevalence of De Quervain’s Tenosynovitis among restaurant Station and Junior chef. Objective: presence Restaurant chef using Finkelstein test. Methodology: -144 subjects were selected from metropolitan cities according to inclusion exclusion criteria. A written informed consent was taken in language best understood by them. The study explained about procedure. test is performed on both hands. positive indicated pain over abductor pollicis longus extensor brevis tendons at...

Underlying disorders of the maxillary sinus (MS), including a history surgeries, chronic sinusitis, or congenital anomalies can potentially impact function and structure, necessitating careful evaluation management. Moreover, intact sinuses are crucial in gender determination forensic anthropology. The present study was undertaken to check accuracy reliability MS using morphometric parameters.