A5101844077- 3D Printing in Biomedical Research
- Electrospun Nanofibers in Biomedical Applications
- Surface Modification and Superhydrophobicity
- Nanofabrication and Lithography Techniques
- Microfluidic and Bio-sensing Technologies
- Microfluidic and Capillary Electrophoresis Applications
- Tissue Engineering and Regenerative Medicine
- Silk-based biomaterials and applications
- Electrohydrodynamics and Fluid Dynamics
- Advanced Sensor and Energy Harvesting Materials
- Neuroscience and Neural Engineering
- Conducting polymers and applications
- Innovative Microfluidic and Catalytic Techniques Innovation
- Additive Manufacturing and 3D Printing Technologies
- Electrowetting and Microfluidic Technologies
- EEG and Brain-Computer Interfaces
- Skin Protection and Aging
- Salivary Gland Disorders and Functions
- Molecular Communication and Nanonetworks
- Herpesvirus Infections and Treatments
- Advanced Biosensing Techniques and Applications
- Heme Oxygenase-1 and Carbon Monoxide
- Optical Coatings and Gratings
- Hydrogels: synthesis, properties, applications
- Effects of Vibration on Health
Harvard University
2024
Pohang University of Science and Technology
2013-2023
Yonsei University
2021
Government of the Republic of Korea
2019
Amorepacific (South Korea)
2016
Seoul St. Mary's Hospital
2004
Catholic University of Korea
2004
MizMedi Hospital
2001
Auxin regulates a variety of physiological and developmental processes in plants. Although auxin acts as suppressor leaf senescence, its exact role this respect has not been clearly defined, aside from circumstantial evidence. It was found here that ARF2 functions the auxin-mediated control Arabidopsis longevity, discovered by screening EMS mutant pools for delayed senescence phenotype. Two allelic mutations, ore14-1 14-2, caused highly significant delay all parameters examined, including...
Abstract The fabrication of a stable, anti‐wetting surface is very challenging issue in chemistry. In general, superhydrophobicity highly depends on the structure. Moreover, mechanical deformation structure can produce dramatic changes wetting state, and some cases, may even result complete loss surface's unique wettability. However, study stable surfaces under conditions has been limited to flexible or small strain. Here, mechanically superhydrophobic membrane presented, which possesses...
Abstract The incidences of various esophageal diseases (e.g., congenital stenosis, tracheoesophageal fistula, atresia, cancer) are increasing, but tissue is difficult to be recovered because its weak regenerative capability. There no commercialized off-the-shelf alternatives current reconstruction and regeneration methods. Surgeons usually use ectopic conduit tissues including stomach intestine, presumably inducing donor site morbidity severe complications. To date, polymer-based substitutes...
Drug-induced cardiotoxicity is regarded as a major hurdle in the early stages of drug development. Although there are various methods for preclinical tests, they cannot completely predict cardiotoxic potential compound due to lack physiological relevance. Recently, 3D engineered heart tissue (EHT) has been used investigate cardiac muscle functions well pharmacological effects by exhibiting auxotonic contractions. However, still no adequate platform continuous monitoring test acute and...
Two hundred thirty-seven expressed sequence tags (ESTs) of Brassica napus were generated by single-run partial sequencing 197 random root cDNA clones. A computer search these ESTs revealed that 21 show significant similarity to the protein-coding sequences in existing data bases, including five stress- or defense-related genes and four clones related from other kingdoms. Northern blot analysis 10 base-matched many are most abundantly but less organs. However, two highly specific. The results...
To date, several off-the-shelf products such as artificial blood vessel grafts have been reported and clinically tested for small diameter (SDV) replacement. However, conventional lack endothelium and, thus, are not ideal SDV transplantation they can cause thrombosis. In addition, a successful graft must sufficient mechanical properties to withstand various external stresses. Here, we developed spontaneous cellular assembly (S-SDV) that develops without additional intervention. By improving...
Abstract Electrodes in traditional electrospinning processes have been used to directly collect nanofibers, or induce a modified electric field aligned nanofibers. In this context, many studies carried out overcome the limitations of simple metal electrodes. study, sub‐millimeter‐scale electrospun nanofiber patterning technique is proposed, which uses functional electrolyte as collector electrode between an and substrate. Adhesion nanofibers substrate promoted by using polydopamine solution...
Abstract In vitro organ models allow for the creation of precise preclinical that mimic physiology. During a pandemic life-threatening acute respiratory disease, an improved trachea model (TM) is required. We fabricated modular assembly blood vessel and TMs using 3D bioprinting technology. First, decellularized extracellular matrix (dECM) were prepared porcine vessels. A module was based on tracheal mucosa-derived dECM microporous membrane. Further, manufactured vascular-tissue-derived dECM....
Microelectrodes are widely used for neural signal analysis because they can record high-resolution signals. In general, the smaller size of microelectrode obtaining a signal, higher impedance and noise value electrodes. Therefore, to improve signal-to-noise ratio (SNR) signals, it is important develop microelectrodes with low noise. this research, an Au hierarchical nanostructure (AHN) was deposited electrochemical surface area (ECSA) microelectrode. nanostructures on different scales were...
Recently, respiratory systems are increasingly threatened by high levels of environmental pollution. Organ-on-a-chip technology has the advantage enabling more accurate preclinical experiments reproducing in vivo organ physiology. To investigate disease mechanisms and treatment options, respiratory-physiology-on-a-chip have been studied for last decade. Here, we delineate strategic approaches to develop that can recapitulate system vitro. The state-of-the-art biofabrication methods...
The extracellular matrix provides mechanical support and affects cell behaviour. Nanoscale structures have been shown to functions similar the matrix. In this study, we fabricated nanoprotrusion with polyaniline as culture plates using a simple method determined effects of these on cells.
We report a novel method to form circular pattern of monodisperse microdroplets using an electrohydrodynamic repulsion (EDR) mechanism. EDR is phenomenon electrostatical bounced from accumulated droplet on bottom substrate. In addition regular system, by placing ring electrode between the capillary and ground substrate, two separate regions were created. A parameter study was carried out for formation falling velocity control radius generated droplets patterns independently. Based energy...
Controlling the architecture of electrospun fibers is one key issues in tissue engineering. This report describes a rapid and reproducible patterning method for fabrication an fibrous scaffold. The were deposited on patterned electrode. scaffold was fabricated using thin insulating film between layers this For engineering application, poly(lactic-co-glycolic acid) (PLGA), biocompatible biodegradable material, electrospun. Fibroblast cells cultured PLGA viability, morphology, distribution studied.
A new saliva pattern modulation method was developed, which can improve ovulation detection accuracy based on electrolyte pre-deposition.
Electrospinning is a technology that can produce nanofibers with high aspect ratio. Generally, the nanofiber produced in this way collected randomly on collector. In article number 1701204 Geon Hwee Kim, Taechang An, Geunbae Lim and co-workers develop electrospinning technique using patterned functional electrolyte as Because through hydrophobicity control substrate, it not affected by thickness of collector possible to pattern aligned locally according patterning electrolyte. The...
Tissue–Sensor Platforms In article number 2208983, Uijung Yong, Donghwan Kim, Hojoong Woon-Hong Yeo, Jinah Jang, and co-workers report a biohybrid 3D-printing method for the fabrication of tissue–sensor platforms. The integration electronics with living cardiac tissues makes it possible to continuously monitor their contractile force and, ultimately, drug-induced cardiotoxicity effects on tissues. This can create next-generation platform an effective drug development process.
Oblique submicron-scale structures are used in various aspects of research, such as the directional characteristics dry adhesives and wettability. Although deposition, etching, lithography techniques applied to fabricate oblique structures, these approaches have problem controllability or throughput structures. Here, we propose a simple X-ray-lithography method, which can control angle with areas on centimeter scale. An X-ray mask was fabricated by gold film deposition slanted Using this...