Francisco Vargas

ORCID: 0000-0003-3158-5411
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About
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Research Areas
  • Aortic aneurysm repair treatments
  • Pleural and Pulmonary Diseases
  • Aortic Disease and Treatment Approaches
  • Cardiac, Anesthesia and Surgical Outcomes
  • Vascular Procedures and Complications
  • Mycobacterium research and diagnosis
  • Neural Networks and Applications
  • Tuberculosis Research and Epidemiology
  • Gaussian Processes and Bayesian Inference
  • Peripheral Artery Disease Management
  • Systemic Lupus Erythematosus Research
  • Trace Elements in Health
  • Model Reduction and Neural Networks
  • Venous Thromboembolism Diagnosis and Management
  • Tracheal and airway disorders
  • Tumors and Oncological Cases
  • Vascular Anomalies and Treatments
  • Liver Disease Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Explainable Artificial Intelligence (XAI)
  • Brucella: diagnosis, epidemiology, treatment
  • Abdominal vascular conditions and treatments
  • Infectious Aortic and Vascular Conditions
  • Lung Cancer Diagnosis and Treatment
  • Vascular anomalies and interventions

Pontificia Universidad Católica de Chile
2011-2025

Costa Rican Department of Social Security
2023-2024

Adolfo Ibáñez University
2024

Universidad de Costa Rica
2023

St. Vincent's Medical Center
2020-2023

Clinica Santa Maria
2023

Federico Santa María Technical University
2022-2023

Sociedad Española de Nefrología
2023

Research Institute Hospital 12 de Octubre
2023

Complejo Hospitalario Dr. Arnulfo Arias Madrid
2017-2022

Design strategies for small diameter vascular grafts are converging toward native-inspired tissue engineered grafts. A new automated technology is presented that combines a dip-spinning methodology depositioning concentric cell-laden hydrogel layers, with an adapted solution blow spinning (SBS) device intercalated placement of aligned reinforcement nanofibres. This additive manufacture approach allows the assembly bio-inspired structural configurations cell patterns fibres at specific angles...

10.1038/s41467-019-11090-3 article EN cc-by Nature Communications 2019-07-15

Proyecto Laúd coordinates the conservation activities for leatherback turtle on 4 index beaches of Mexican Pacific, combining efforts different government and nongovernment institutions. With more than 20 years tagging data, this project represents most solid source knowledge about biology ecology in Mexico. Daily nesting track counts done from 1982 to 2004 showed a declining trend number nests Pacific (Mexiquillo, Tierra Colorada, Cahuitán, Barra de la Cruz). The worst season was 2002–2003,...

10.2744/1071-8443(2007)6[70:cabotl]2.0.co;2 article EN Chelonian Conservation and Biology 2007-05-01

Diffusion models are an important tool for generative modelling, serving as effective priors in applications such imaging and protein design. A key challenge applying diffusion downstream tasks is efficiently sampling from resulting posterior distributions, which can be addressed using the $h$-transform. This work introduces a self-supervised algorithm fine-tuning by estimating $h$-transform, enabling amortised conditional sampling. Our method iteratively refines $h$-transform synthetic...

10.48550/arxiv.2502.04468 preprint EN arXiv (Cornell University) 2025-02-06

We consider the sampling problem, where aim is to draw samples from a distribution whose density known only up normalization constant. Recent breakthroughs in generative modeling approximate high-dimensional data have sparked significant interest developing neural network-based methods for this challenging problem. However, samplers typically incur heavy computational overhead due simulating trajectories during training. This motivates pursuit of simulation-free training procedures samplers....

10.48550/arxiv.2502.06685 preprint EN arXiv (Cornell University) 2025-02-10

In Spanish primary care (PC), the prevalence of fragility fractures (FF) in subjects ≥ 70 years old is high, especially women. One-third with an FF lacked osteoporosis (OP) diagnosis and >50% were not currently receiving OP medication. An improvement management this population needed.In PC, a more than half Several studies reported underdiagnosis/undertreatment PC among elderly FF. To date, no such data exist for Spain. The purpose to estimate (≥ old) describe characteristics, risk factors,...

10.1007/s11657-022-01124-7 article EN cc-by Archives of Osteoporosis 2022-07-14

The goal of this article was to characterize the clinical evolution scrapie in naturally affected sheep. Eighteen sheep with diagnosed by examination 3rd eyelid biopsy and 12 control ewes were studied throughout duration their disease. Diagnosis confirmed postmortem histopathologic, immunohistochemical, Western blot analysis nervous tissue. Complete examinations performed every 2 weeks for each animal, which 3 per animal are reported. Those signs that showed a significant frequency within...

10.1892/0891-6640(2006)20[187:daceos]2.0.co;2 article EN Journal of Veterinary Internal Medicine 2006-01-01

The goal of this article was to characterize the clinical evolution scrapie in naturally affected sheep. Eighteen sheep with diagnosed by examination 3rd eyelid biopsy and 12 control ewes were studied throughout duration their disease. Diagnosis confirmed postmortem histopathologic, immunohistochemical, Western blot analysis nervous tissue. Complete examinations performed every 2 weeks for each animal, which 3 per animal are reported. Those signs that showed a significant frequency within...

10.1111/j.1939-1676.2006.tb02840.x article EN Journal of Veterinary Internal Medicine 2006-01-01

Abstract Summary This study demonstrated a large treatment gap in elderly subjects experiencing fragility fracture Spanish primary care, low persistence among who do receive treatment, and more than one-quarter having no follow-up visits post-fracture. These data highlight the need to improve secondary prevention care. Purpose To describe osteoporosis (OP) patterns with seen care (PC). Methods observational, retrospective chart review included aged ≥ 70 years listed centers' records...

10.1007/s11657-024-01394-3 article EN cc-by Archives of Osteoporosis 2024-05-09

Antibodies, crucial for immune defense, primarily rely on complementarity-determining regions (CDRs) to bind and neutralize antigens, such as viruses. The design of these CDRs determines the antibody's affinity specificity towards its target. Generative models, particularly denoising diffusion probabilistic models (DDPMs), have shown potential advance structure-based CDR regions. However, only a limited dataset bound antibody-antigen structures is available, generalization...

10.48550/arxiv.2406.05832 preprint EN arXiv (Cornell University) 2024-06-09

Monte Carlo methods, Variational Inference, and their combinations play a pivotal role in sampling from intractable probability distributions. However, current studies lack unified evaluation framework, relying on disparate performance measures limited method comparisons across diverse tasks, complicating the assessment of progress hindering decision-making practitioners. In response to these challenges, our work introduces benchmark that evaluates methods using standardized task suite broad...

10.48550/arxiv.2406.07423 preprint EN arXiv (Cornell University) 2024-06-11

Inhibitors of DNA binding/inhibitors differentiation (Id) protein family have been shown to be involved in carcinogenesis. However, the roles Id during lung adenocarcinoma (ADC) progression remain unclear. Eighty-eight ADC samples were evaluated for Id-1,2,3 level and angiogenesis (CD 34 VEGF microvessel density) by immunohistochemistry morphometry. The impact these markers was tested on follow-up until death or recurrence. A significant difference between tumor normal tissue found...

10.1177/1535370216632623 article EN Experimental Biology and Medicine 2016-02-10

The representation space of neural models for textual data emerges in an unsupervised manner during training. Understanding how human-interpretable concepts, such as gender, are encoded these representations would improve the ability users to control content and analyze working that rely on them. One prominent approach problem is identification removal linear concept subspaces – correspond a given concept. While those tractable interpretable, network do not necessarily represent concepts...

10.18653/v1/2022.emnlp-main.405 article EN cc-by Proceedings of the 2021 Conference on Empirical Methods in Natural Language Processing 2022-01-01

Dialysis patients have a different response than the non-dialysis population to infection with COVID-19. This study evaluates prevalence of and lethality in receiving hemodialysis or peritoneal dialysis Panama, compared adult population, reports adverse events vaccination.This is prospective, multi-center cohort spatients aged 18 years older in-center ambulatory 13 centers Panama from March 2021 2022. For comparison general used an extended period two years.A total 1531 treatment accepted...

10.1007/s11255-023-03529-w article EN cc-by International Urology and Nephrology 2023-02-24

Denoising diffusion models are a popular class of generative providing state-of-the-art results in many domains. One adds gradually noise to data using transform the distribution into Gaussian distribution. Samples from model then obtained by simulating an approximation time-reversal this initialized samples. Practically, intractable score terms appearing time-reversed process approximated matching techniques. We explore here similar idea sample approximately unnormalized probability density...

10.48550/arxiv.2302.13834 preprint EN other-oa arXiv (Cornell University) 2023-01-01

We report a case of primary breast lymphoma which was incidentally detected in 71 year-old-female while investigating for pulmonary embolism with Computed tomography angiograph (CTA) the chest. Primary has no specific imaging features however may have better prognosis than carcinoma and management is non-surgical.

10.1016/j.radcr.2020.11.009 article EN cc-by-nc-nd Radiology Case Reports 2020-11-20
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