- Parkinson's Disease Mechanisms and Treatments
- Family and Disability Support Research
- Neural and Behavioral Psychology Studies
- Family Support in Illness
- Memory Processes and Influences
- Stroke Rehabilitation and Recovery
- Health Systems, Economic Evaluations, Quality of Life
- Face Recognition and Perception
- Family Caregiving in Mental Illness
- Chronic Disease Management Strategies
- Memory and Neural Mechanisms
- Childhood Cancer Survivors' Quality of Life
- Ethics in medical practice
- Long-Term Effects of COVID-19
- Palliative Care and End-of-Life Issues
- Neuroscience, Education and Cognitive Function
- Neurobiology of Language and Bilingualism
- Mathematics Education and Teaching Techniques
- Cognitive and developmental aspects of mathematical skills
- Visual and Cognitive Learning Processes
- Dementia and Cognitive Impairment Research
- Neuroscience and Music Perception
- Health disparities and outcomes
- Parkinson's Disease and Spinal Disorders
- Telemedicine and Telehealth Implementation
Rush University Medical Center
2019-2022
Urban College of Boston
2022
Institute of Neurological Sciences
2020
University of Chicago
2018
University of Massachusetts Chan Medical School
2018
University of California, Berkeley
2008-2012
Lawrence Berkeley National Laboratory
2011
Northwestern University
2005
McGill University Health Centre
2000
Individual differences in executive functions (EFs) are well established to be related mathematics achievement, yet the mechanisms by which this occurs not understood. Comparing representations (problems, solutions, concepts) is central mathematical thinking, and relational reasoning known rely upon EF resources. The current manuscript explored whether individual predicted learning from a conceptually demanding lesson requiring reasoning. Analyses revealed that variations when measured at...
Advanced Parkinson's disease (PD) is a multidimensional neurodegenerative condition with motor and non-motor symptoms contributing to increasing disability decreasing quality of life. As the progresses, patients may become homebound estranged from neurological care, dire consequences. We describe epidemiologic burden individual risks faced by palliative-stage PD their caregivers.
The coronavirus disease 2019 (COVID-19) pandemic has upended daily life and neurologic care for most patients, including those with Parkinson’s parkinsonism. Disruptions to routine care, high volumes of patient caregiver calls, our patients’ risk infection complications inspired a proactive COVID-19 outreach program. This program targets patients advanced related disorders, specifically who are homebound, receiving or eligible palliative and/or lacking support networks. We describe the...
The current understanding of advanced Parkinson disease (PD) and its treatment is largely based on data from outpatient visits. most disabled individuals with PD are disconnected both care research. A previous pilot study among older, multimorbid patients demonstrated the feasibility interdisciplinary home visits to reach target population, improve quality, potentially avoid institutionalization.The aim this protocol investigate whether can prevent a decline in quality life worsening...
Fever is a common presentation to urgent-care services and linked multiple disease processes. To rapidly determine the etiology of fever, improved diagnostic modalities are necessary. This prospective study 100 hospitalized febrile patients included both positive (FP) negative (FN) subjects in terms infection status 22 healthy controls (HC). We evaluated performance novel PCR-based assay measuring five host mRNA transcripts directly from whole blood differentiate infectious versus...
Homebound individuals with advanced Parkinson disease (PD) require intensive caregiving, the majority of which is provided by informal, family caregivers. PD caregiver strain an independent risk factor for institutionalization. There are currently no effective interventions to support Studies in other neurologic disorders, however, have demonstrated potential peer mentoring improve outcomes. In context ongoing trial interdisciplinary home visits, we designed and piloted a nested informal...
Sunday, April 26April 14, 2020Free AccessDisparities in Access to Care and Research Participation Advanced Parkinson’s Disease: Differences between a Home Visit Study Outpatient Clinic Population (4413)Jori Fleisher, Ellen Klostermann, Erica Myrick, Serena Hess, Jeanette Lee, Bichun Ouyang, Deborah Hall, Joshua ChodoshAuthors Info & AffiliationsApril 2020 issue94 (15_supplement)https://doi.org/10.1212/WNL.94.15_supplement.4413 Letters the Editor
Micro RNA (miRNA) are noncoding RNAs that involved in gene silencing and transcriptional regulation.microRNAs transcribed as long stem-loop structures (pri-miRNA).These molecules undergo double-stranded cleavage by the enzyme drosha nucleus to form a shorter called pre-miRNA.After export from cytoplasm, pre-miRNA undergoes another dicer eventually mature miRNA of 20-22 nucleotide residues length.miR-21 is considered an "onco-miR" because it one family micro upregulated some cancers.To...