A5063948929- Parkinson's Disease Mechanisms and Treatments
- Hearing, Cochlea, Tinnitus, Genetics
- Dementia and Cognitive Impairment Research
- Chronic Disease Management Strategies
- Photoreceptor and optogenetics research
- Balance, Gait, and Falls Prevention
- Health disparities and outcomes
- Stroke Rehabilitation and Recovery
- Health Systems, Economic Evaluations, Quality of Life
- Cerebral Palsy and Movement Disorders
- Neural dynamics and brain function
- Neuroscience and Neuropharmacology Research
Rush University Medical Center
2021-2022
Yale University
2020-2021
Abstract In the developing auditory system, spontaneous activity generated in cochleae propagates into central nervous system to promote circuit formation. The effects of peripheral firing patterns on are not well understood. Here, we describe wide-spread bilateral coupling that coincides with period transient efferent modulation inner hair cells from brainstem medial olivocochlear system. Knocking out α9/α10 nicotinic acetylcholine receptors, a requisite part pathway, profoundly reduces...
Background Multiple exercise modalities and mindfulness activities are beneficial in Parkinson's Disease (PD). Karate is a martial art that combines aerobic large-amplitude movements, balance core training, mindfulness, suggesting potential benefit for individuals with PD from multiple perspectives. Objective To evaluate the feasibility of community-based Shotokan karate classes involving physical activity among mild- to moderate-stage PD, explore effects on objective patient-reported...
The current understanding of advanced Parkinson disease (PD) and its treatment is largely based on data from outpatient visits. most disabled individuals with PD are disconnected both care research. A previous pilot study among older, multimorbid patients demonstrated the feasibility interdisciplinary home visits to reach target population, improve quality, potentially avoid institutionalization.The aim this protocol investigate whether can prevent a decline in quality life worsening...
Summary In the developing auditory system, spontaneous activity generated in cochleae propagates into central nervous system to promote circuit formation before hearing onset. Effects of evolving peripheral firing pattern on are not well understood. Here, we describe wide-spread bilateral coupling that coincides with period transient efferent modulation inner hair cells from medial olivochlear (MOC) system. Knocking out α9/α10 nicotinic acetylcholine receptor, a requisite part cholinergic...
<sec> <title>BACKGROUND</title> The current understanding of advanced Parkinson disease (PD) and its treatment is largely based on data from outpatient visits. most disabled individuals with PD are disconnected both care research. A previous pilot study among older, multimorbid patients demonstrated the feasibility interdisciplinary home visits to reach target population, improve quality, potentially avoid institutionalization. </sec> <title>OBJECTIVE</title> aim this protocol investigate...