- Antibiotic Use and Resistance
- Antibiotic Resistance in Bacteria
- Pneumonia and Respiratory Infections
- Patient Satisfaction in Healthcare
- Streptococcal Infections and Treatments
- Bacterial Identification and Susceptibility Testing
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Animal Disease Management and Epidemiology
- Clostridium difficile and Clostridium perfringens research
- COVID-19 Pandemic Impacts
- Gut microbiota and health
- Vibrio bacteria research studies
- Mobile Health and mHealth Applications
- Influenza Virus Research Studies
- Animal Behavior and Welfare Studies
- Respiratory viral infections research
- Data-Driven Disease Surveillance
- Nosocomial Infections in ICU
- Frailty in Older Adults
- Otolaryngology and Infectious Diseases
- Agricultural Systems and Practices
- ICT in Developing Communities
- demographic modeling and climate adaptation
Oxford University Clinical Research Unit
2014-2025
Hospital for Tropical Diseases
2019-2025
Posts and Telecommunications Institute of Technology - Ho Chi Minh City
2024
Vietnam National University, Hanoi
2024
Animal, Santé, Territoires, Risques et Ecosystèmes
2020
BackgroundInappropriate antibiotic use for acute respiratory tract infections is common in primary health care, but distinguishing serious from self-limiting difficult, particularly low-resource settings. We assessed whether C-reactive protein point-of-care testing can safely reduce patients with non-severe Vietnam.MethodWe did a multicentre open-label randomised controlled trial ten health-care centres northern Vietnam. Patients aged 1–65 years at least one focal and systemic symptom of...
Bloodstream infections (BSIs) are associated with high morbidity and mortality worldwide. However their aetiology, antimicrobial susceptibilities outcomes differ between developed developing countries. Systematic data from Vietnam scarce. Here we present aetiologic on BSI in adults admitted to a large tertiary referral hospital for infectious diseases Hanoi, Vietnam.A retrospective study was conducted at the National Hospital Tropical Diseases January 2011 December 2013. Cases of were...
Abstract Objective To analyse data from 2016–17 a hospital-based antimicrobial resistance surveillance with national coverage in network of hospitals Viet Nam. Methods We analysed 13 hospitals, 3 less than the dataset 2012–13 period. Identification and susceptibility testing clinical microbiology laboratories samples sent for routine diagnostics were used. Clinical Laboratory Standards Institute 2018 guidelines used interpretation. WHONET was entry, management analysis. Results 42,553...
There is scarce information regarding hospital-acquired infections (HAIs) among children in resource-constrained settings. This study aims to measure prevalence of HAIs Vietnamese pediatric hospitals. Monthly point surveys (PPSs) 6 intensive care units (ICUs) 3 referral hospitals during 1 year. A total 1363 cases (1143 children) were surveyed, 59.9% male, average age 11 months. Admission sources were: other hospital 49.3%, current 36.5%, and community 15.3%. Reasons for admission infectious...
Influenza household transmission studies are required to guide prevention strategies but most passively recruit index cases that seek healthcare. We investigated A(H1N1)pdm09 in a household-based cohort during 2009.Health-workers visited 270 households weekly, and collected swabs from influenza-like-illness cases. If was RT-PCR-confirmed, all members had symptoms assessed daily for 10-15 days. Viral RNA quantified sequenced serology performed on pre-pandemic sera.Index were detected 20...
To establish a hospital-based surveillance network with national coverage for antimicrobial resistance (AMR) and antibiotic consumption in Viet Nam.A 16-hospital (Viet Nam Resistance: VINARES) was established consisted of provincial-level hospitals across the country. Antimicrobial susceptibility testing results from routine clinical diagnostic specimens data Defined Daily Dose per 1000 bed days (DDD/1000 patient-days) were prospectively collected analysed between October 2012 September...
This study aims to investigate patterns of antibiotic prescribing and determine patient-specific factors associated with the choice antibiotics by World Health Organization's Access-Watch-Reserve (WHO AWaRe) class for acute respiratory infections (ARIs) in rural primary care settings northern Vietnam. We retrospectively reviewed health records outpatients who were registered Vietnamese Insurance Scheme, visited one 112 commune centres 6 districts Nam Dinh province, Vietnam during 2019,...
In previous trials, point-of-care testing of C-reactive protein (CRP) concentrations safely reduced antibiotic use in non-severe acute respiratory infections primary care. However, these trials were done a research-oriented context with close support from research staff, which could have influenced prescribing practices. To better inform the potential for scaling up CRP infections, we aimed to do pragmatic trial intervention routine care setting.We did pragmatic, cluster-randomised...
<ns3:p>Introduction Recent reports indicate the emergence of community-acquired pneumonia associated with K64- <ns3:italic>Klebsiella pneumoniae (K. pneumoniae)</ns3:italic>. Here, we identify capsular types and sequence type invasive commensal <ns3:italic>K. pneumoniae</ns3:italic> isolates from Vietnam. Methods We included 93 patients hospitalized at National Hospital for Tropical Diseases, Hanoi between 2007 2011; 110 throat swabs healthy volunteers living in rural urban 2012. determined...
We assessed the impact of MALDITOF-MS on timeliness optimal antimicrobial therapy through a parallel-arm randomised controlled trial in two hospitals Vietnam.We recruited patients with pathogen (bacterial or fungal) cultured from normally sterile sample. Samples were randomly assigned (1:1) to identification by conventional diagnostics. The primary outcome was proportion within 24 h positive culture, determined blinded independent review committee. Trial registered at ClinicalTrials.gov...
Background Influenza constitutes a leading cause of morbidity and mortality worldwide. There is limited information about the aetiology infection presenting clinically as influenza in hospitalised adults children South‐East Asia. Such data are important for future management respiratory infections. Objectives To describe those Methods Respiratory specimens archived from July 2008 to June 2009 patients with suspected Indonesia, Thailand Vietnam were tested viruses atypical bacteria by...
Abstract The first nationwide outbreak of COVID-19 in Vietnam started late April 2021 and was caused almost exclusively by a single Delta lineage, AY.57. In early 2022, multiple Omicron variants co-circulated with quickly became dominant. co-circulation happened leading to possibility co-infection recombination events which can be revealed viral genomic data. From January October total 1028 RNA samples out 4852 positive (Ct < 30) were sequenced the long pooled amplicons method on Illumina...
ObjectivesStreptococcus suis is a zoonotic cause of severe meningitis and sepsis in humans. We aimed to assess the long-term outcomes patients who survived S. infection, particular progress impact vestibulocochlear sequelae.MethodsThis case-control study evaluated infection at discharge 3 9 months post-discharge for 47 prospectively enrolled cases 11–34 31 retrospectively cases. Outcomes were compared 270 controls matched age, sex residency.ResultsThe prevalence ratio (PR)...
In recent years, serosurveillance has gained momentum as a way of determining disease transmission and immunity in populations, particularly with respect to vaccine-preventable diseases. At the end 2017, Oxford University Clinical Research Unit National Institute Hygiene Epidemiology held meeting Vietnam national policy makers, researchers, international experts discuss current seroepidemiologic projects future needs plans for nationwide serosurveillance. This report summarizes that were...
Comprehensive insight into the microbiota of gut humans and animals, as well their living environment, in communities with a high background antibiotic use resistance genes is scarce. Here, we used 16S rRNA gene sequencing to describe (dis)similarities feces from (n = 107), domestic animals 36), water 89), processed food 74) cohort individual history northern Vietnam. A significantly lower microbial diversity was observed among individuals who antibiotics past 4 months 44) compared those did...
<ns3:p><ns3:bold>Background: </ns3:bold>When the novel coronavirus – SARS-CoV-2 started to spread globally, there was a call for social and behavioral scientists conduct research explore wider socio-cultural contexts of disease 2019 (COVID-19), understand vulnerabilities, as well increase engagement within communities facilitate adoption public health measures. In this manuscript, we describe protocol study conducted in Indonesia, Nepal, Vietnam. study, how COVID-19 pandemic is affecting...
Background: This study aims to investigate patterns of antibiotic prescribing and determine patient-specific factors associated with the choice antibiotics by World Health Organization’s Access-Watch-Reserve (WHO AWaRe) class for acute respiratory infection (ARIs) in rural primary care settings northern Vietnam.Methods: We retrospectively reviewed health records outpatients who were registered Vietnamese Insurance Scheme, visited one 112 commune centres 6 districts Nam Dinh province, Vietnam...
Abstract Background Older patients typically face elevated mortality rates and greater medical resource utilization during hospitalizations compared to their younger counterparts. Sarcopenia, serving as a prognostic indicator, is related disability, diminished quality of life, increased mortality. The SARC-F questionnaire, known for its cost-effectiveness, offers valuable means assessing sarcopenia. Method Participants aged 60 above, admitted the Cardiovascular Department from November 2021...
Introduction Older patients typically face elevated mortality rates and greater medical resource utilization during hospitalizations compared to their younger counterparts. Sarcopenia, serving as a prognostic indicator, is related disability, diminished quality of life, increased mortality. The SARC-F questionnaire, known for its cost-effectiveness, offers valuable means assessing sarcopenia. This study aims explore the association between scores risk adverse outcomes in elderly with...
This study aims to advance understanding of the factors affecting Generation Z employee commitment in workplace information and technology (IT) companies Vietnam. A survey 450 employees IT shows that company remuneration, reward welfare, work environment, colleagues, direct manager, promotion, job characteristics, green initiatives are positively related organizational commitment. More specifically, environment manager have highest effect on organization while promotion colleagues lowest...
<sec> <title>BACKGROUND</title> Health research requires high-quality data, and population-based health comes with specific opportunities challenges. Electronic data collection can mitigate some of the challenges working large populations in multiple, sometimes difficult to reach, locations. </sec> <title>OBJECTIVE</title> To discuss opportunities, challenges, solutions when using Research Data Capture (REDCap) for designing, collecting, managing data. <title>METHODS</title> We implemented...