A5026345561- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Neutropenia and Cancer Infections
- Cancer Treatment and Pharmacology
- Economic and Financial Impacts of Cancer
- Medical Imaging Techniques and Applications
- Heart Failure Treatment and Management
- Multiple Myeloma Research and Treatments
- Neurosurgical Procedures and Complications
- Advanced MRI Techniques and Applications
- Safe Handling of Antineoplastic Drugs
- Lanthanide and Transition Metal Complexes
- Social and Demographic Issues in Germany
- Clinical practice guidelines implementation
- Blood Pressure and Hypertension Studies
- Inflammatory Myopathies and Dermatomyositis
- Takotsubo Cardiomyopathy and Associated Phenomena
- Genetic Neurodegenerative Diseases
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Orthopedic Surgery and Rehabilitation
- COVID-19 and healthcare impacts
- MRI in cancer diagnosis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Viral Infections and Immunology Research
- Immune Response and Inflammation
University Hospital of Zurich
2016-2024
University of St. Gallen
2023-2024
Kantonsspital St. Gallen
2023-2024
Gesellschaft für Klinische Forschung
2023
Zurich Heart House
2021
University Hospital of Basel
2019
University of Basel
2019
Kantonsspital Baden
2018
University Medical Center Freiburg
2006-2017
University of Freiburg
2017
Methods have been devised for obtaining gadolinium(III) complexes of the ligands NOTA (1,4,7-triazacyclononane-N,N',N''-triacetic acid), DOTA (1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetic TETA (1,4,8,11-tetraazacyclotetradecane-N,N',N'',N'''-tetraacetic and DTPA (diethylenetriaminepentaacetic acid) as solids use pharmaceuticals. Their effectiveness in vitro vivo contrast agents NMR imaging or T1,2 relaxation spectroscopy has investigated. The Gd(DOTA) complex was shown to be a...
Abstract Purpose This study aims to describe the experience of Swiss oncological patients during COVID-19 pandemic. Methods A national multi-center including five hospitals covering three main language regions Switzerland was conducted between March and July 2021. Patients with melanoma, breast, lung, or colon cancer receiving active systemic anti-cancer treatment at time pandemic were included. We semi-structured telephone onsite interviews alongside administration distress...
Epicardial adipose tissue (EAT) is a metabolically highly active modulating numerous pathophysiological processes. The aim of this study was to investigate the association between EAT thickness and endothelial function in patients with heart failure (HF) across entire ejection fraction spectrum.A total 258 HF an spectrum [HF reduced (HFrEF), n = 168, age 60.6 ± 11.2 years; preserved (HFpEF), 50, mean 65.1 11.9 mildly (HFmrEF), 32, 65 12] were included. measured transthoracic...
Gadolinium cryptelates are complexes of a lanthanide metal ion with amino acids macrocyclic polyamines. These compounds water soluble and possess reduced relaxation properties similar to Gd diethylene triamine pentaacetic acid (DTPA). Three (Gd NOTA, DOTA, TETA) were evaluated. DOTA is the most stable complex dissociation constant 10-28 appears have greater serum stability than DTPA. NOTA TETA lower constants DTPA at 10-17 10-19. has tissue distribution rapidly excreted by kidneys, provides...
ABSTRACT Background Mineralocorticoid receptor antagonists ( MRAs ) reduce morbidity and mortality in heart failure with reduced ejection fraction HFrEF ). Their role patients without failure, particularly coronary artery disease CAD preserved EF , is still a matter of debate. Hypothesis The MRA eplerenone on top standard medical therapy improves endothelial dysfunction other markers vascular health . Methods In this double‐blind, randomized, placebo‐controlled study, 42 (mean age: 63.5 ±...
Im Rahmen des KeSBa-Projekts wurde über einen Zeitraum von drei Monaten die Machbarkeit eines Routinescreenings bei Palliativpatienten mittels „Integrated Palliative Outcome Scale“ (IPOS) oder Minimalem Dokumentationssystem (MIDOS) getestet. Wie sah Rolle der onkologischen Fachpflege Durchführung dieses aus? Was war hinderlich und welche Empfehlungen gibt es? Auswertung einer Fokusgruppendiskussion nach Beendigung Erhebungsphase Hinderliche Faktoren waren (1) Defizite IT-Umsetzung, (2)...
Background. During the COVID-19 pandemic, people affected by cancer were in need of information about virus and (self-) management symptoms treatment. It is important to understand how patients with navigated through pandemic explore their experience relating supportive care needs. Aim. This study aimed describe Swiss oncological during additional care. Methods. A single-center was conducted 2021. Patients melanoma, breast, lung, or colon who received active systemic anticancer treatment at...
Abstract Background Systemic sclerosis (SSc) is a chronic autoimmune disease characterized by widespread and progressive multi-organ fibrosis vascular abnormalities. Endothelial dysfunction an early manifestation of SSc important contributor to the progression prognosis disease. Dynamic retinal analysis (DVA) new method for non-invasive precise determination microvascular function. The primary aim was assess micro- macro-vascular function in patients with SSc. Methods In this study, measured...