- Endodontics and Root Canal Treatments
- Dental Radiography and Imaging
- Dental materials and restorations
- Neuroinflammation and Neurodegeneration Mechanisms
- Drilling and Well Engineering
- Moyamoya disease diagnosis and treatment
- Generative Adversarial Networks and Image Synthesis
- Alzheimer's disease research and treatments
- Advanced Image Processing Techniques
- Macrophage Migration Inhibitory Factor
- Advanced Vision and Imaging
- Apelin-related biomedical research
- Central Venous Catheters and Hemodialysis
- RNA regulation and disease
- Advanced Nanomaterials in Catalysis
- Thyroid Disorders and Treatments
- Vascular anomalies and interventions
- Gene expression and cancer classification
- Occupational Health and Safety Research
- Climate variability and models
- Occupational health in dentistry
- Nuclear Receptors and Signaling
- Oral microbiology and periodontitis research
- Salivary Gland Disorders and Functions
- Hemodynamic Monitoring and Therapy
Hanyang University
2013-2023
Gangneung–Wonju National University
2010-2020
Hanyang University Seoul Hospital
2020
Kangwon National University Hospital
2015
Ewha Womans University
2015
Seoul National University Hospital
2015
Significance Parkinson’s disease (PD) is the most prevalent movement disorder with no available treatments that can stop or slow down progress. Although orphan nuclear receptor Nurr1 a promising target for PD, it thought to be ligand-independent transcription factor and, so far, small molecule has been identified bind its ligand binding domain. Here, we established high throughput cell-based assays and successfully three agonists among FDA-approved drugs, all sharing an identical chemical...
Mitochondria are important organelles that regulate adenosine triphosphate production, intracellular calcium buffering, cell survival, and apoptosis. They play therapeutic roles in injured cells via transcellular transfer through extracellular vesicles, gap junctions, tunneling nanotubes. Astrocytes can secrete numerous factors known to promote neuronal synaptic formation, plasticity. Recent studies have demonstrated astrocytes mitochondria damaged neurons enhance their viability recovery....
This study aimed to investigate the incidence and location of second mesiobuccal root (MB2) canal in maxillary molars with aid various measuring points lines using cone-beam computed tomography (CT).A total 205 images patients who underwent CT examinations between 2011 2015 as part their dental diagnosis treatment were included. There 76 first molar 135 molar. Canal orifices detected at -1 mm from top pulpal floor on images. Image assessment was performed by 2 observers reformatted image...
This study was conducted to examine the effect of oral care with an aroma solution on status and cavity microorganism growth in elderly patients stroke.A non-equivalent control group, a pretest-posttest design used this study. The participants were assigned experimental group (n=30) that received or (n=31) 0.9% saline solution. To identify treatments, objective/subjective assessments performed using assessment guide, perception swab culture. Data analyzed Chi-square test, Fisher's exact...
Recent learning-based video inpainting approaches have achieved considerable progress. However, they still cannot fully utilize semantic information within the frames and predict improper scene layout, failing to restore clear object boundaries for mixed scenes. To mitigate this problem, we introduce a new transformer-based technique that can exploit input considerably improve reconstruction quality. In study, use mixture-of-experts scheme train multiple experts handle scenes, including...
The replacement of missing teeth, especially in the anterior region, is an essential part dental practice.Fiber-reinforced composite resin bridges are a conservative alternative to conventional fixed prostheses or implants.It minimally invasive, reversible technique that can be completed single visit.The two cases presented herein exemplify treatment rootfractured teeth with natural pontic immediately after extraction.
Abstract Abnormalities in gene expression that negatively affect embryonic development are frequently observed cloned embryos generated by somatic cell nuclear transfer (SCNT). In the present study, we successfully produced a cell-penetrating peptide (CPP)-conjugated with coactivator-associated arginine methyltransferase 1 (CARM1) protein from mammalian cells and confirmed introduction into donor 8-cell within 3 hours after addition to culture medium. addition, H3R17 dimethylation up...
No studies have yet assessed vibration characteristics according to endodontic file length. Accordingly, the objective of present study was examine nickel-titanium length and compare these between different systems.A total 45 root canal models were divided into 3 experimental groups (n = 15 each) based on system used (ProTaper Gold [PTG], ProTaper Next, or WaveOne [WOG]). Each group further subgroups (21, 25, 31 mm). An electric motor (X-SMART PLUS) in experiment. For each system, vibrations...
The objective of this paper was to develop a generally applicable formula estimate correct catheter length after surgical cutdown in right internal jugular vein (RIJV) neonates. carina has been utilized as an anatomic landmark indicating superior vena cava-right atrium junction (SVC-RA) for the optimal placement central venous (CVC) tip position. However, may not be accurate Recent researches noted that sixth vertebral body (T6) could better serve new SVC-RA neonates and smaller children. We...
Introduction: Stem cell therapy (SCT) has been proposed for the treatment of neurological disorders. Although there isinsufficient clinical evidence to support its efficacy, unproven SCTs are being performed worldwide. Hypothesis: In this study, we investigated perspectives and expectations chronic ischemic stroke patients physicians about SCTs. Methods: A total 250 were interviewed at 4 hospitals. Structured open closed questions SCT asked by trained interviewers using conventional...
Introduction: Silent brain infarcts (SBI) are seen on computed topography or magnetic resonance imaging without any clinical symptoms suggestive of transient ischemic attack stroke. SBI associated with the risk subsequent stroke and dementia. Various inflammatory markers have been reported to correlate SBI. After Cilostazol Stroke Prevention Study, many studies focused anti-inflammatory effect cilostazol. Hypothesis: We investigated cilostazol in patients silent by measuring temporal profile...
Introduction : Stroke is one of the most common causes chronic disability and death. Although prediction stroke outcome important, predictors still remain unclear. Vascular endothelial growth factor (VEGF), stromal cell-derived factor-1α (SDF-1α), macrophage migration inhibitory (MIF), high mobility group box 1 (HMGB1) have been reported to play critical roles in neurovascular remodeling or mediating inflammation at acute subacute phase after ischemic stroke. Hypothesis Wehypothesized that...
ABSTRACT Ⅰ. 서 론 방사선불투과도(radiopacity)는구강내치과재료에요구되는중요한특성중의하나이다. 치과진료의진단은방사선사진에크게의존하고있고주위해부학적구조물들과의경계를명확히하고수복물의적합도, 이차우식증, 장기안정성의지속적검사를위해치과수복재료의방사선불투과도는중요하다. 1-3) 수종의섬유강화레진포스트의방사선불투과도와식별도평가 이은혜 1 ∙최항문 2 ∙박세희 ∙김진우∙조경모*강릉원주대학교치과대학 치과보존학교실, 구강악안면방사선학교실 EVALUATION OF RADIOPACITY AND DISCRIMINABILITY VARIOUS FIBER REINFORCED COMPOSITE POSTS Eun-Hye Lee , Hang-Moon Choi Se-Hee Park Jin-Woo Kim Kyung-Mo Cho * Department of Conservative Dentistry, Oral and maxillofacial radiology, College...
서론 근관치료의 기본적인 원칙 중 하나는 감염되거나 괴사 된 치수조직과 미생물을 근관계에서 제거하는 것이며, 이 것은 가장 결정적이고 중요한 성공 요건으로 작용한다. 1,2그러나 리본 형태, 타원형의 근관, 좁은 협부 (isthmus) 등과 같은 해부학적인 이유로 근관 내 많은 부 위가 기계적으로 세정이 불가능하며, 이로 인해 세균이 나 다른 미생물들이 잔존하게 된다
Objectives: The primer (G-Cem One Adhesive Enhancing Primer), which promote self-polymerization more in the absence of polymerization light is developed. To date, many studies on mechanical properties and prognosis various self-adhesive resin cements have been published. Since there almost no comparison degree depending application primers, this study was attempted. Materials Methods: A total three types dual cure One, G-Cem LinkAce, Rely-X U200) one type cement (Rely-X Ultimate) were...
이 연구는 산재근로자의 경제활동 변화 유형과 미충족의료 경험과의 관계를 파악하는 것을 목적으로 한다. 유형은 산재보험패널데이터를 활용하여 2018년과 2019년의 상태에 따라 4개 유형으로 구분하였다. 경험 여부는 조사결과를 활용하였으며, 경제활동변화 관련성을 알아보기 위해 로지스틱 회귀분석을 실시하였다. 연구결과 경험률은 7.7%로 한국의료패널에서 조사한 한국 성인의 경험률(10.7%)보다 낮았고, 취업상태를 유지하고 있는 산재근로자에 비해 취업-미취업 상태인 경험률이 1.58배 높은 것으로 나타났다. 따라서 해소를 위해서는 직장복귀 및 고용유지를 위한 제도를 활성화하고, 경제활동을 할 수 없는 산재보험 보장성이 강화되어야 것이다.
Abstract The frequency and duration of extreme heat events, including waves (HWs, daytime hot extremes) tropical night (TNs), are increasing significantly as the climate warms, adversely affecting human health, agriculture, energy consumption. Although many detection attribution studies have examined underlying mechanisms associated with recent increase in HWs TNs remain unclear. In this study, we analyze controlling factors behind distinct increases HW TN events over Northern Hemisphere...
Recent image inpainting methods have shown promising results due to the power of deep learning, which can explore external information available from large training dataset. However, many state-of-the-art networks are still limited in exploiting internal given input at test time. To mitigate this problem, we present a novel and efficient self-supervised fine-tuning algorithm that adapt parameters fully pre-trained without using ground-truth target images. We update by utilizing existing...