A5100661916- Microbial Metabolic Engineering and Bioproduction
- Axon Guidance and Neuronal Signaling
- biodegradable polymer synthesis and properties
- Neurogenesis and neuroplasticity mechanisms
- RNA Research and Splicing
- Advancements in Battery Materials
- Ion channel regulation and function
- Nerve injury and regeneration
- Plant Molecular Biology Research
- RNA and protein synthesis mechanisms
- Ion Transport and Channel Regulation
- Olfactory and Sensory Function Studies
- Metabolomics and Mass Spectrometry Studies
- Enzyme Catalysis and Immobilization
- Supercapacitor Materials and Fabrication
- Reading and Literacy Development
- Carbon dioxide utilization in catalysis
- Cancer, Lipids, and Metabolism
- Pharmacological Effects of Natural Compounds
- Microbial Community Ecology and Physiology
- Healthcare Education and Workforce Issues
- Ginseng Biological Effects and Applications
- Behavioral and Psychological Studies
- Education and Learning Interventions
- Advanced Battery Materials and Technologies
Korea Institute of Energy Research
2013-2025
University of North Carolina at Chapel Hill
2024
University of Nevada, Reno
2008-2024
Seoul National University
2002-2024
Korea Polar Research Institute
2023-2024
Seoul Women's University
2020-2024
Sungkyunkwan University
2012-2024
Korea Institute of Nuclear Safety
2024
Samsung (South Korea)
2016-2024
Southern California Clinical and Translational Science Institute
2023
We have generated 47,932 T-DNA tag lines in japonica rice using activation-tagging vectors that contain tetramerized 35S enhancer sequences. To facilitate use of those lines, we isolated the genomic sequences flanking inserted via inverse polymerase chain reaction. For most performed four sets amplifications two different restriction enzymes toward both directions. In analyzing 41,234 obtained 27,621 sequence tags (FSTs), among which 12,505 were integrated into genic regions and 15,116...
Significance Most of the single miRNA gene knockouts display no developmental phenotype. Here, we report that simultaneous inactivation two functionally overlapping miRNAs, miR-34b/c and miR-449, led to a sexually dimorphic partial perinatal lethality, growth retardation sterility. Multiple underlying defects, including underdevelopment basal forebrain structures, lack motile cilia in trachea oviduct, severely disrupted spermatogenesis oligoasthenoteratozoospermia, result from dysregulation...
Significance When starved for nutrients, diatoms redirect carbon toward biosynthesis of storage lipids, triacylglycerols (TAGs). We examined how this modification is achieved in the diatom Phaeodactylum tricornutum. Under nitrogen stress, cells cannibalized their photosynthetic apparatus while recycling intracellular and redirecting it to synthesize assimilation enzymes. Simultaneously, they allocated newly fixed lipids. In contrast, a nitrate reductase knocked-down strain shunted ∼40% more...
We consider dimension reduction for regression or classification in which the predictors are matrix- array-valued. This type of predictor arises when measurements obtained each combination two more underlying variables--for example, voltage measured at different channels and times electroencephalography data. For these applications, it is desirable to preserve array structure reduced (e.g., time versus channel), but this cannot be achieved within conventional formulation. In paper, we...
Summary Diatoms (Bacillarophyceae) are photosynthetic unicellular microalgae that have risen to ecological prominence in oceans over the past 30 million years. They of interest as potential feedstocks for sustainable biofuels. Maximizing production these will require genetic modifications and an understanding algal metabolism. These processes may benefit from genome‐scale models, which predict intracellular fluxes theoretical yields, well viability knockout knock‐in transformants. Here we...
Computers can be an effective teaching method for students with learning disabilities (LD). The use of mobile devices as education tools has received considerable attention in special recently. Parents, teachers, and professionals look applications (i.e., apps) that meet the needs their children students. This is often challenging them due to large number apps are available market. article introduces describes evaluation rubric developed help parents, other evaluate LD.
ABSTRACT Staphylococcus aureus is a formidable human pathogen that uses secreted cytolytic factors to injure immune cells and promote infection of its host. Of these proteins, the bicomponent family pore-forming leukocidins play critical roles in S. pathogenesis. The regulatory mechanisms governing expression toxins are incompletely defined. In this work, we performed screen identify transcriptional regulators involved leukocidin strain USA300. We discovered metabolic sensor-regulator,...
Lithium-ion batteries (LIBs) can be considered as one of the pivotal components required to succeed in drive towards a greener future. However, current processing methods for cathode electrode make it harmful and costly due toxic solvent drying recovery stages. Additionally, reliance on LIBs particularly emphasizes imperative increased energy density both volume weight, which predominantly relies cathode. To surmount these challenges, this research analyses true requirements novel process...
Bentonite, which is used as an engineered barrier in geological repositories, ineffective for sorbing anionic radionuclides because of its negatively charged surface. This study modified raw bentonite using a cationic surfactant (i.e., hexadecyltrimethylammonium [HDTMA]-Br) to improve sorption capability radioactive iodide. The effects temperature and radiation on the iodide surfactant-modified (SMB) were also evaluated under alkaline pH condition similar that found repository environments....
Abstract In the prospective Korean Cancer Prevention Study-II (KCPS-II), we investigated application of metabolomics to differentiate subjects with incident hepatocellular carcinoma (HCC group) from who remained free cancer (control during a mean follow-up period 7 years aim identifying valuable metabolic biomarkers for HCC. We used baseline serum samples 75 HCC and 134 age- gender-matched cancer-free subjects. Serum profiles associated incidence were via analysis. Compared control group,...
Mitochondria are important organelles that regulate adenosine triphosphate production, intracellular calcium buffering, cell survival, and apoptosis. They play therapeutic roles in injured cells via transcellular transfer through extracellular vesicles, gap junctions, tunneling nanotubes. Astrocytes can secrete numerous factors known to promote neuronal synaptic formation, plasticity. Recent studies have demonstrated astrocytes mitochondria damaged neurons enhance their viability recovery....