A5001578727- Cardiac Imaging and Diagnostics
- Cardiac Ischemia and Reperfusion
- Hemodynamic Monitoring and Therapy
- Cardiovascular Function and Risk Factors
- Mechanical Circulatory Support Devices
- Cardiac pacing and defibrillation studies
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac electrophysiology and arrhythmias
- Wind Energy Research and Development
- Cardiac Health and Mental Health
- Optical Imaging and Spectroscopy Techniques
- Coronary Interventions and Diagnostics
- Congenital Heart Disease Studies
- Animal Genetics and Reproduction
- Cardiac Structural Anomalies and Repair
- Ultrasound and Hyperthermia Applications
- Cardiac Arrest and Resuscitation
- Cardiac Arrhythmias and Treatments
- Cardiac and Coronary Surgery Techniques
- Reproductive Biology and Fertility
- Respiratory Support and Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Health and Disease Prevention
- Fluid Dynamics and Vibration Analysis
- Thermoregulation and physiological responses
Heinz Maier-Leibnitz Zentrum
2025
Forschungszentrum Jülich
2025
Uppsala University
2021-2023
Institute for Telematics
2007
Philips (Germany)
2005
Philips (Finland)
2003
Evangelisches Krankenhaus Kalk
2001
Elisabeth-Krankenhaus Essen
1999
Ludwig Boltzmann Institute for Digital Health and Prevention
1998
University of Veterinary Medicine Vienna
1989-1998
Abstract: Megakaryocytes are difficult to isolate because of their fragility, tendency aggregate, and varying sizes. For purification cells at different stages maturation sizes (ploidy classes) we developed an immunomagnetic cell sorting method (MACS) enrich the whole spectrum megakaryocytic lineage. The use small magnetic beads coupled various antibodies labelling with fluorescent allowed direct analysis enrichment evaluation isolated fraction without further staining or detachment...
The helix approach is a new individual pitch control method to mitigate wake effects of wind turbines. Its name derived from the helical shape caused by rotating radial force exerted turbine. While its potential increase power production has been shown in previous studies, physics are not well understood date. Open questions include whether increased momentum stems an enhanced mixing or deflection. Furthermore, application row more than two turbines examined before. We study this depth both...
The KWS-2 small-angle neutron scattering (SANS) diffractometer operated by Jülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum, Garching, Germany, is dedicated to the investigation of mesoscopic multi-scale structures and structural changes due rapid kinetic processes in soft condensed matter biophysical systems. Following requests from user community, it has been repeatedly upgraded with respect most important methodological parameters an instrument this type, namely...
For indicator-dilution studies, complete thermal recovery after passage of heat through the pulmonary circulation would be desirable. However, results in literature obtained by extrapolation techniques are inconsistent. To overcome problems approach, transport functions (including left heart) were computed deconvolution arterial and aortic pairs thermodilution curves central venous indicator injection (10 ml an ice-cold blood indocyanine green dye mixture). Thermal was determined as finite...
Abstract The use of graphics processing units (GPUs) has facilitated unprecedented performance gains for computational fluids dynamics in recent years. In many industries this enabled the integration large-eddy simulation (LES) engineering practice. Flow modelling wind industry though still primarily relies on models with significantly lower fidelity. This paper seeks to investigate reasons why energy applications LES are an exception industrial On that account, we present a survey among...
Temporary cardiac pacing (CP) is frequently applied postoperatively in the management of low output (CO) and rhythm instability. However, uncertainty exists about "optimal" rate, range mode due to incomplete information on myocardial oxygen consumption (MVO2), related its hemodynamic determinants, pumping efficiency (eta) at CP. In 10 intact dogs atrial (AP) (90 210 beats/min) ventricular (VP) (70 330 were investigated normal failing hearts. AP VP compared identical rates. MVO2 (4 20 ml/min...
Abstract Optimal control of wind farms to maximize power is a challenging task since the wake interaction between turbines highly nonlinear phenomenon. In recent years field Reinforcement Learning has made great contributions problems and been successfully applied optimization in 2D laminar flows. this work, farm for first time authors’ best knowledge. To demonstrate abilities newly developed framework, parameters an already existing strategy, helix approach, are tuned optimize total...
This report describes a rare case of an asymptomatic myocardial abscess which was not associated with infective endocarditis but diagnosed to be tumor and treated by open-heart surgery. A 69-year-old patient without history or infarction submitted invasive cardiac diagnostics after embolic event in the brachial artery. Investigation revealed "intracardiac tumor" subsequently underwent After cardiotomy suggested found posterior wall left atrium adjacent mitral ring, appearing as...
We studied the heterogeneity of myocardial blood flow in nine anesthetized closed-chest dogs using an indicator-dilution technique that allows stochastic description transport characteristics for three inert gases (helium, argon, and xenon) from coronary inflow to outflow. The results show under normal conditions transcoronary tracers is spatially heterogeneous. Heterogeneity strongly dependent on arterial oxygen tension over a range 40–200 Torr. This could be similarly observed with each...
Wolpers HG, Baller D, Hoeft A, Korb H, Schräder R, Zipfel J, Helligc G. The effect of ion composition on cellular membrane potentials during selective coronary arteriography. Invest Radiol 1984;19:291-295. An animal experimental study seven thoracotomized dogs was designed to investigate the effects intracoronarily injected sodium meglumine diatrizoate moycardial electrophysiology and evaluate contribution corresponding changes electrolyte levels in blood. For this purpose alterations Na+-,...
Abstract Deep convolutional neural networks are a promising machine learning approach for computationally efficient predictions of flow fields. In this work we present simple modelling framework the prediction time-averaged three-dimensional field wind turbine wakes. The proposed model requires mean inflow upstream turbine, aerodynamic data and tip-speed ratio as input data. output comprises all three velocity components well turbulence intensity. is trained with statistics 900 actuator line...
In patients undergoing thoracic surgery central blood volume is subject to large variations and extravascular lung water may change critically due fluid shifts. Therefore, an accurate monitoring of these parameters, in particular under perioperative conditions, seems be desirable. This study describes improved method for the measurement intrathoracic volumes.
In premature, very-low-birth-weight (VLBW) neonates, complex cardiac malformations can be successfully repaired under conditions of cardiopulmonary bypass. However, due to the immaturity organ Systems, these patients are exposed a specific risk resulting from noxious effects extracorporeal circulation, especially on central nervous System. Two premature neonates with low and very birth weight 1160 g 1650 g, were operated using bypass for severe pulmonary artery stenosis truncus arteriosus...
The aim of this study was to examine whether contractility and endothelial function the human saphenous vein prepared for aortocoronary bypass grafting are altered by surgical technique, e. g. cannulation gentle distension vessel. Two Segments (2 cm Iength each) native vena saphena magna 2 same vessel coronary were taken further experimentation. After ligation all side branches segments cannulated arranged in two Systems (with a serial manner (system I: followed segment; system II: segment)...
Considerable elevations of left ventricular diastolic pressure in relation to cardiac volume are often observed clinical situations such as angina pectoris, acute myocardial infarction and low output syndrome after cardiopulmonary bypass. Both a calcium-related increase resting tension contracture have been held responsible for the altered properties under hypoxic conditions. However, an experimental approach suggesting evidence occurrence calcium-induced tone intact beating heart with...