Lourival Carvalho Nunes

ORCID: 0000-0003-3181-5205
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About
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Research Areas
  • Fungal Infections and Studies
  • Microbial Natural Products and Biosynthesis
  • Antifungal resistance and susceptibility
  • Phytochemical compounds biological activities
  • Photodynamic Therapy Research Studies

Universidade de Brasília
2024-2025

Background/Objectives: Curcumin has antimicrobial activity, and its mechanism of action involves changing histone acetylation. Our group shown that deacetylases (HDACs) inhibitors increase the sensibility Cryptococcus neoformans to certain antifungal treatments. Therefore, aim this work was investigate whether curcumin pretreatment increases effect photodynamic therapy (PDT) mediated by aluminum phthalocyanine in nanoemulsion (AlPc-NE) against C. neoformans. Methods: The minimum inhibitory...

10.3390/ph18020240 article EN cc-by Pharmaceuticals 2025-02-11
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