Zhongwen Long

ORCID: 0000-0003-3193-1804
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Biosensors and Analytical Detection
  • Advanced Antenna and Metasurface Technologies
  • Covalent Organic Framework Applications
  • Photoacoustic and Ultrasonic Imaging
  • Plasmonic and Surface Plasmon Research
  • Electrospun Nanofibers in Biomedical Applications
  • Metamaterials and Metasurfaces Applications
  • Advanced Optical Imaging Technologies
  • Reproductive System and Pregnancy
  • Sperm and Testicular Function
  • Advanced Photocatalysis Techniques
  • Extracellular vesicles in disease
  • Reproductive Physiology in Livestock

Collaborative Innovation Center of Advanced Microstructures
2017-2024

Nanjing University
2017-2024

Beijing University of Chinese Medicine
2021

Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine
2021

A low-cost, large scale plasmonic metasurface sensing platform shows enormous potential for highly sensitive and selective SERS-based glucose detection.

10.1039/d0nr00288g article EN Nanoscale 2020-01-01

A metallic nanoring array supports two plasmonic modes with a complementary sensing scheme for detecting broad range of biomolecules.

10.1039/c7nr07124h article EN Nanoscale 2017-11-13

Nanomaterials excel in mimicking the structure and function of natural enzymes while being far more interesting terms structural stability, functional versatility, recyclability, large-scale preparation. Herein, story assembles hemin, histidine analogs, G-quadruplex DNA a catalytically competent supramolecular assembly referred to as assembly-activated hemin enzyme (AA-heminzyme). The catalytic properties AA-heminzyme are investigated both silico (by molecular docking quantum chemical...

10.1002/advs.202402237 article EN cc-by Advanced Science 2024-06-25

Abstract Digital imaging immunoassays for precisely detecting microRNAs have attracted much attention in early cancer diagnosis. Currently, there is an urgent demand improving the sensitivity and selectivity digital immunoassays, which limited by low signal‐to‐noise ratio pollutant interference. Herein, a plasmon‐enhanced ultrasensitive selective digital‐readout immunoassay reported microRNA quantification. Through DNA hybridization technology, Au nanoparticles are bound to target...

10.1002/adfm.202210561 article EN Advanced Functional Materials 2022-11-28

The phase-shifting structured light illumination technique is widely used in imaging but often relies on mechanical translation stages or spatial modulators, leading to system instability, low displacement accuracy, and limited integration feasibility. In response these challenges, we propose demonstrate an approach for generating far-field using a polarization multiplexing metasurface. By controlling the states of incident transmitted light, metasurface creates three-step eliminating need...

10.1021/acs.nanolett.4c03142 article EN Nano Letters 2024-08-26

This study aimed to verify that Xuefu Zhuyu decoction (XFZYD) can improve asthenozoospermia caused by asthma, and explore its potential mechanism. Ovalbumin solution is used induce asthma rat models. Sperm concentration motility are evaluate semen quality. Immunohistochemistry (IHC), Western blotting real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR) detect proteins mRNA related testis tissue. Haematoxylin eosin (H&E) staining was observe changes in testicular...

10.1111/and.14198 article EN Andrologia 2021-08-10

Digital-Resolution Biosensing In article number 2210561, Ting Xu, Yuzhang Liang, Cheng Yang, and co-workers report a plasmon-enhanced ultrasensitive selective digital-readout imaging immunoassay for microRNA quantification. The molecules are translated into digitally distinguishable nanoparticle attachment onto large-area Au-SiO2 bilayer film, forming plasmonic nanocavity enhanced digital spots in dark-field images. Additionally, convolutional neural network algorithm is developed to assist...

10.1002/adfm.202370031 article EN Advanced Functional Materials 2023-02-01
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