A5026755587- Mosquito-borne diseases and control
- Malaria Research and Control
- Insect Pest Control Strategies
- Insect symbiosis and bacterial influences
- Advanced Fiber Optic Sensors
- Insect Resistance and Genetics
- Photonic and Optical Devices
- Vector-borne infectious diseases
- Insect and Pesticide Research
- Insect and Arachnid Ecology and Behavior
- Photonic Crystals and Applications
- Studies on Chitinases and Chitosanases
- Entomopathogenic Microorganisms in Pest Control
- Parasitic Diseases Research and Treatment
- Plant Virus Research Studies
- Viral Infections and Vectors
- Mechanical and Optical Resonators
- Advanced Biosensing Techniques and Applications
Queensland University of Technology
2022-2023
The University of Texas Medical Branch at Galveston
2023
Universidade de São Paulo
2023
London School of Hygiene & Tropical Medicine
2019-2022
Ifakara Health Institute
2019-2021
University of London
2019-2021
University of Missouri
2005-2006
We have developed a highly sensitive refractometric sensor based on fused silica microsphere resonators. The spectral position of the whispering gallery mode (WGM) sphere shifts in response to refractive index change surrounding medium. strong light-matter interaction due extremely high Q factor associated with WGM results sensitivity approximately 30nm∕RIU (refractive units). This, together resolution our system (∼0.01pm), yields detection limit order 10−7RIU. Theoretical calculation is...
Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for Plasmodium infections (RDTs). This study investigated whether mid-infrared (MIR) spectroscopy coupled with supervised machine learning could constitute an alternative method screening, directly from dried human blood spots.Filter papers containing spots (DBS) were obtained a cross-sectional survey in 12 wards southeastern Tanzania 2018/19. The DBS scanned...
Abstract Background Eave ribbons treated with spatial repellents effectively prevent human exposure to outdoor-biting and indoor-biting malaria mosquitoes, could constitute a scalable low-cost supplement current interventions, such as insecticide-treated nets (ITNs). This study measured protection afforded by transfluthrin-treated eave users (personal communal protection) non-users (only protection), whether introducing mosquito traps additional intervention influenced these benefits....
Dengue is an arboviral disease caused by dengue virus (DENV), leading to approximately 25,000 deaths/year and with over 40% of the world’s population at risk. Increased international travel trade, poorly regulated urban expansion, warming global temperatures have expanded geographic range incidence in recent decades. This study used phylogenetic selection pressure analyses investigate trends DENV evolution, using whole genome coding sequences from publicly available databases alongside newly...
In recent years, the scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has greatly reduced malaria transmission. However, remains a global public health concern with majority disease burden in sub-Saharan Africa. Insecticide resistance is growing problem among Anopheles vector populations, potential implications for continued effectiveness available control interventions. Improved understanding current levels underlying mechanisms essential to design...
Abstract Surveillance of malaria vector species and the monitoring insecticide resistance are essential to inform control strategies support reduction infections disease. Genetic barcoding mosquitoes is a useful tool assist high-throughput surveillance resistance, discriminate between sibling detect presence Plasmodium infections. In this study, we combined multiplex PCR, custom designed dual indexing, Illumina next generation sequencing for high throughput single nucleotide polymorphism...
Anopheles arabiensis and funestus sensu stricto mosquitoes are major East African malaria vectors. Understanding their dispersal population structure is critical for developing effective control tools. Three mark-release-recapture (MRR) experiments were conducted 51 nights to assess daily survival flight range of An. in south-eastern, Tanzania. Mosquitoes marked with a fluorescent dye as they emerged from breeding sites via self-marking device. collected indoors outdoors using human landing...
Abstract Background Spatial repellents that drive mosquitoes away from treated areas, and odour-baited traps, attract kill mosquitoes, can be combined work synergistically in a push-pull system. Push-pull systems have been shown to reduce house entry outdoor biting rates of malaria vectors so the potential control other such as Aedes aegypti transmit arboviral diseases. In this study, semi-field experiments were conducted evaluate whether system could used bites mosquitoes. Methods The push...
Wolbachia , a widespread bacterium which can influence mosquito-borne pathogen transmission, has recently been detected within Anopheles ( An .) species that are malaria vectors in Sub-Saharan Africa. Although studies have reported strains the An. gambiae complex, apparent low density and prevalence rates require confirmation. In this study, wild mosquitoes collected from two regions of Guinea were investigated. contrast with previous studies, RNA was extracted adult females n = 516) to...
Abstract Background Epidemiological surveys of malaria currently rely on microscopy, polymerase chain reaction assays (PCR) or rapid diagnostic test kits for Plasmodium infections (RDTs). This study shows that mid-infrared (MIR) spectroscopy coupled with supervised machine learning could constitute an alternative method screening, directly from dried human blood spots. Methods Filter papers containing spots (DBS) were obtained a cross-sectional survey in twelve wards south-eastern Tanzania...
Whispering Gallery Modes (WGMs) in microsphere ring resonators enable excellent sensitivity due to the high Q-factor (> 10<sup>6</sup>) that significantly increases light-matter interaction. The analytes attached sphere surface change local refractive index, leading a spectral shift resonances of WGM. A practical microsphere-based sensor must detect minute changes index. In addition, should be functionalized for subsequent binding bio/chemical molecules. Both functionalization and processes...
1. Summary Wolbachia , a widespread bacterium which can influence mosquito-borne pathogen transmission, has recently been detected within Anopheles (An.) species that are malaria vectors in Sub-Saharan Africa. Although studies have reported strains the An. gambiae complex, apparent low density and prevalence rates require confirmation. In this study, wild mosquitoes collected from two regions of Guinea were investigated. contrast to previous studies, RNA was extracted adult females (n=516)...
We have carried out the refractometric characterization on whispering gallery mode (WGM) of a fused silica microsphere as first step towards developing novel bio/chemical sensors with high sensitivity and multiplexing capability. The WGM spectral position shifts when refractive index surrounding medium is varied by adding ethanol to water. It found that 30 nm/RIU (refractive units) detection limit order 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML"...
Abstract Background: Spatial repellents that drive mosquitoes away from treated area, and odour-baited traps, attract kill mosquitoes, can be combined work synergistically in a push-pull system. Push-pull systems have shown to reduce house entry outdoor biting rates of malaria vectors so the potential control other such as Aedes aegypti transmit arboviral diseases. In this study, semi-field experiments were conducted evaluate whether system could used bites . Methods: The push pull under...
5) Severe dengue cases frequently occur in tempo-spatial clusters implying the importance to find out sources of infection.The overlapping areas between high mosquito indices and facilitate transmission persistence.(6) Source reduction is more effective than insecticide-spraying.Conclusion: integrated surveillance systems, immediate interrupting transmission, identifying breeding sites all together can reduce epidemic severity thus promoting global health.
Abstract Background In recent years, the scale-up of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has greatly reduced malaria transmission. However, remains a global public health concern with majority disease burden in sub-Saharan Africa. Insecticide resistance is growing problem among Anopheles vector populations, potential implications for continued effectiveness available control interventions. Improved understanding current levels underlying mechanisms...
Abstract Background The use of volatile pyrethroids and odor-baited traps in a push-pull system has been shown to reduce house entry outdoor bites for malaria vectors. This technology the potential control other biting mosquitoes such as Aedes aegypti that transmit arboviral diseases. In this study, semi-field experiments were conducted evaluate whether could be used from . Methods push pull under investigation consisted two freestanding transfluthrin passive emanators (FTPE), BG sentinel...
Abstract Background: Spatial repellents that drive mosquitoes away from treated areas, and odour-baited traps, attract kill mosquitoes, can be combined work synergistically in apush-pull system. Push-pull systems have been shown to reduce house entry outdoor biting rates of malaria vectors so the potential control other such as Aedes aegypti transmit arboviral diseases. In this study, semi-field experiments were conducted evaluate whether a push-pull system could used bites mosquitoes....