The factors affecting oil yield and quality of essential oils from Dalmatian sage (Salvia officinalis L.) are analyzed. Distillations individual plants GC analyses revealed the presence three chemotypes with different proportions α- β-thujone (α/β 10:1, 1.5:1, 1:10). Different accessions could also be classified as having high (39−44%), medium (22−28%), or low (9%) total thujone contents. Flowering parts S. had higher contents (1.6 versus 1.1%) β-pinene levels (27 10%) than leaves lower (16...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMycalamide A, an antiviral compound from a New Zealand sponge of the genus MycaleNigel B. Perry, John W. Blunt, Murray H. G. Munro, and Lewis K. PannellCite this: J. Am. Chem. Soc. 1988, 110, 14, 4850–4851Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://pubs.acs.org/doi/10.1021/ja00222a067https://doi.org/10.1021/ja00222a067research-articleACS PublicationsRequest reuse...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiscorhabdin C, a highly cytotoxic pigment from sponge of the genus LatrunculiaNigel B. Perry, John W. Blunt, D. McCombs, and Murray H. G. MunroCite this: J. Org. Chem. 1986, 51, 26, 5476–5478Publication Date (Print):December 1, 1986Publication History Published online1 May 2002Published inissue 1 December 1986https://pubs.acs.org/doi/10.1021/jo00376a096https://doi.org/10.1021/jo00376a096research-articleACS PublicationsRequest reuse...

We evaluated the potential of apple to reduce inflammation. Phenolic compounds and triterpenes were analyzed in 109 cultivars. Total phenolics ranged from 29 7882 μg g(-1) fresh weight (FW) flesh 733 4868 FW skin, with flavanols including epicatechin procyanidins as major components. Ursolic (44.7 3522 FW) oleanolic (47.2 838 acids dominated skin triterpene profile. Five chemically contrasting cultivars fractionated their immune-modulating activity measured using two cell-based assays...

A proposed standard extraction and HPLC analysis method has been used to measure typical levels of various phenolic compounds in the medicinally Echinacea species. Chicoric acid was main E. purpurea roots (mean 2.27% summer, 1.68% autumn) tops (2.02% 0.52% autumn), echinacoside angustifolia (1.04%) pallida (0.34%). Caftaric other compound (0.40% 0.35% (0.82% 0.18% cynarin a characteristic component (0.12%). Enzymatic browning during could reduce measured by >50%. Colorimetric analyses for...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntiviral and antitumor agents from a New Zealand sponge, Mycale sp. 2. Structures solution conformations of mycalamides A BNigel B. Perry, John W. Blunt, Murray H. G. Munro, Andrew M. ThompsonCite this: J. Org. Chem. 1990, 55, 1, 223–227Publication Date (Print):January 1990Publication History Published online1 May 2002Published inissue 1 January 1990https://pubs.acs.org/doi/10.1021/jo00288a037https://doi.org/10.1021/jo00288a037research-articleACS...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiscorhabdin D, an antitumor alkaloid from the sponges Latrunculia brevis and Prianos spNigel B. Perry, John W. Blunt, Murray H. G. Munro, Tatsuo Higa, Ryuichi SakaiCite this: J. Org. Chem. 1988, 53, 17, 4127–4128Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/jo00252a052https://doi.org/10.1021/jo00252a052research-articleACS PublicationsRequest...

Abstract The seasonal variation in essential oil yield and composition from naturalized Thymus vulgaris L. Central Otago, New Zealand, is reported. Essential (l/ha), replicated, pilot‐scale distillations, was influenced by both the field production of herb content herb. peaked at 22.8 l/ha December, after flowering had finished. also varied significantly during 13‐month sampling period. Levels phenolic components, thymol carvacrol, a total 37% summer (December January). p ‐Cymene an...

Two pyridopyrrolopyrimidine alkaloids, variolin A (2) and N(3′)-methyl tetrahydrovariolin B (3), have been isolated from the Antarctic sponge Kirkpatrickia varialosa, their structures determined by X-ray crystallography interpretation of spectral data respectively. N(3′)-Methyl (3) is moderately cytotoxic showed antifungal activity, while weakly cytotoxic.

• Red-pigmented leaf margins are common, but their functional significance is unknown. We hypothesized that red reduce herbivory by signalling to herbivorous insects the presence of increased chemical defences. Leaves were collected from a natural population Pseudowintera colorata. Margin size, damage, anthocyanin content and concentrations polygodial, sesquiterpene dialdehyde with antifeedant properties, quantified. Feeding trials involving larvae Ctenopseustis obliquana, generalist...

Summary Whether plants use leaf colour to deter herbivores remains controversial. The warning signal hypothesis predicts that red pigmentation is adaptive by reducing herbivory; with predominantly foliage should have higher fitness than those green leaves. Despite many discussions, this prediction has rarely been tested, and alternative, non‐exclusive hypotheses cannot be ruled out. We exploited polymorphism in P seudowintera colorata test the address possible alternative explanations....

Abstract A total of 69 species lichens have been collected from various locations around New Zealand. Screening extracts these for antimicrobial, antiviral and cytotoxic activity showed a high proportion with biological activity. Active were generally known to contain phenolic compounds. Bioactivity-directed isolation work on Cladia retipora, Pseudocyphellaria glabra P. homoeophylla led the identification usnic acid as main component in three species.

Ginger, black pepper, and chili powder were extracted using near-critical carbon dioxide, propane, dimethyl ether on a laboratory scale to determine the overall yield extraction efficiency for selected pungent components. The temperature dependency of was also determined pepper propane ether. pungency extracts by an NMR technique developed this work. volatiles contents ginger determined. Extraction all spice types carried out with acetone compare yields. Subcritical as effective at...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Cytotoxic and Antifungal 1,4-Naphthoquinone Related Compounds from a New Zealand Brown Alga, Landsburgia quercifoliaNigel B. Perry, John W. Blunt, Murray H. G. MunroCite this: J. Nat. Prod. 1991, 54, 4, 978–985Publication Date (Print):July 1, 1991Publication History Published online1 July 2004Published inissue 1 1991https://pubs.acs.org/doi/10.1021/np50076a009https://doi.org/10.1021/np50076a009research-articleACS PublicationsRequest reuse...

Ascidiathiazones A (3) and B (4), two new tricyclic thiazine-containing quinolinequinone alkaloids, were isolated from the New Zealand ascidian Aplidium species. Both compounds inhibited in vitro production of superoxide by PMA-stimulated human neutrophils a dose-dependent manner with IC50 1.55 ± 0.32 0.44 0.09 μM, respectively. In vivo inhibition peritoneal murine model gout was observed for both oral doses 25.6 μmol/kg. Ascidiathiazone synthesized four steps 8-hydroxyquinoline-2-carboxylic acid.

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReverse Phase Flash Chromatography: A Method for the Rapid Partitioning of Natural Product ExtractsJohn W. Blunt, Victoria L. Calder, Graham D. Fenwick, Robin J. Lake, John McCombs, Murray H. G. Munro, and Nigel B. PerryCite this: Nat. Prod. 1987, 50, 2, 290–292Publication Date (Print):March 1, 1987Publication History Published online1 July 2004Published inissue 1 March...

The betalain pigments in ulluco (Ullucus tuberosus), a tuberous crop native to the Andes, have been investigated for first time using LC−DAD−ESI-MS−MS2 analyses. Five red, yellow, and red-spotted accessions introduced into New Zealand as new food plus two red tetraploid lines were investigated. Thirty-two different betalains identified. Both yellow tubers rich betaxanthins, most prominent among 20 identified histidine-betaxanthin, arginine-betaxanthin glutamine-betaxanthin....

Rapid quantitative near-infrared Fourier transform Raman analyses of the key phytonutrients in carrots, polyacetylenes and carotenoids, are reported here for first time. Solvent extracts 31 carrot lines were analyzed these by conventional methods, GC-FID carotenoids visible spectrophotometry. Carotenoid concentrations 0-5586 μg g(-1) dry weight (DW). Polyacetylene 74-4846 DW, highest wild carrots. The falcarinol, 6-1237 DW; falcarindiol, 42-3475 falcarindiol 3-acetate, 27-649 DW. Strong...

Fast MS techniques have been applied to the analysis of sulfur volatiles in Allium species and varieties distinguish phenotypes. Headspace sampling by proton transfer reaction (PTR) surface desorption electrospray ionization (DESI) were used lachrymatory factor synthase (LFS)-silenced (tearless; LFS-) onions from normal, LFS-active (tear-inducing; LFS+), onions. PTR-MS showed lower concentrations (LF, 3) dipropyl disulfide 12 tearless DESI-MS confirmed decreased LF 3 revealed much higher...