A5042199070- Temporomandibular Joint Disorders
- Orthodontics and Dentofacial Orthopedics
- Facial Nerve Paralysis Treatment and Research
- Osteoarthritis Treatment and Mechanisms
- Dental Research and COVID-19
- Extracellular vesicles in disease
- Oral microbiology and periodontitis research
- Salivary Gland Disorders and Functions
- Dental Implant Techniques and Outcomes
- Musculoskeletal synovial abnormalities and treatments
- Mesenchymal stem cell research
- Inflammation biomarkers and pathways
- Oral Health Pathology and Treatment
- Reinforcement Learning in Robotics
- Epigenetics and DNA Methylation
- dental development and anomalies
- Adaptive Control of Nonlinear Systems
- Chemokine receptors and signaling
- Dental Anxiety and Anesthesia Techniques
- Periodontal Regeneration and Treatments
- Bone health and treatments
- Empathy and Medical Education
- Dental Radiography and Imaging
- Immune cells in cancer
- Medicinal Plants and Bioactive Compounds
State Key Laboratory of Oral Diseases
2018-2025
Sichuan University
2018-2025
Zhejiang University
2024
Stomatology Hospital
2020-2024
Zhengzhou University
2022
West China Hospital of Sichuan University
2020
Confronting the outbreak of COVID-19, this cross-sectional study was aimed to assess psychological status temporomandibular disorders (TMD) patients, orthodontic patients and general population in China during pandemic. An online anonymous questionnaire developed Chinese, including individual background information, perception epidemic, level anxiety depression through Kessler Psychological Distress Scale (K10). The respondents were divided into ORTHO group, TMD group Control group....
Titanium (Ti)-based implants play a significant role in rigid internal fixation maxillofacial surgery. No study has reported that three-dimensional-printed Ti alloy plates (3D-Ti plates) have comprehensively excellent properties similar to standard (Matrix-MANDIBLE, SYNTHES, Switzerland) (Synthes-Ti plates). In this work, we manufactured 3D-Ti by selective laser melting with Ti6Al4V powder. The surface morphology, mechanical properties, and bone-plate contact rate of the Synthes-Ti were...
Abstract The ambiguity of etiology makes temporomandibular joint osteoarthritis (TMJOA) “difficult-to-treat”. Emerging evidence underscores the therapeutic promise exosomes in management. Nonetheless, challenges such as low yields and insignificant efficacy current exosome therapies necessitate significant advances. Addressing lower strontium (Sr) levels arthritic synovial microenvironment, we studied effect Sr element on miRNA selectively loading mesenchymal stem cells (SMSCs). Here,...
Yinyuan Longqi 隱元隆琦 was a pivotal figure in Sino–Japanese cultural exchange. His journey to Japan propagate Buddhism, founding of the Ōbaku sect (Huangbo zong 黃檗宗), emphasis on orthodoxy his Zen teachings, and crafting an “authentic” identity profoundly influenced Japanese Buddhism culture. While existing studies have predominantly explored socio–historical dimensions Yinyuan’s construction “authenticity” (benzhen 本真), extensive corpus verses remains understudied. By tracing “Huangbo”...
Periodontitis is one of the most prevalent chronic inflammatory diseases with impaired autophagy. Agaricus blazei Murrill polysaccharide (ABMP) shows beneficial effects in various diseases. However, whether ABMP involved autophagy regulation and periodontitis attenuation remains to be elucidated.This study firstly dynamic changes levels silk ligature model. Then positive effect on inflammation its vital role inhibiting PDLCs response are testified LPS-treated PDLCs. Secondly, Micro-CT,...
Temporomandibular joint osteoarthritis (TMJ-OA) causes severe symptoms such as chewing difficulties, acute pain and even maxillofacial deformity. However, there is hardly any effective disease-curing strategy because of uncertainty in aetiology. Animal model an excellent tool to investigate the mechanism, prevention treatment on diseases. Currently, although several TMJ-OA animal models have been established, are almost no comparative studies different models, which poses a great challenge...
Purpose. To evaluate the relationship between oral habits, psychological status, and temporomandibular-related quality of life among college students. Materials Methods. An online questionnaire was sent to students who were willing participate in this anonymous survey, which contained questions about demographic characteristics participants, Patient Health Questionnaire for Depression Anxiety (PHQ-4), Fonseca Anamnestic Index (FAI), Oral Impact Profile temporomandibular disorders...
Minocycline is a commonly used drug for adjunctive therapy in periodontal disease. However, the current mainstream local medications primarily rely on intra-pocket administration, which, while avoiding side effects of traditional systemic drugs, presents challenges such as inconvenience, discomfort, and need professional assistance, thus affecting patient compliance. Herein, we introduce minocycline-loaded dissolvable microneedle (Mino-DMN) patch that allows efficient delivery minocycline to...
Bone stromal cells are critical for bone homeostasis and regeneration. Growing evidence suggests that non-stem niche support regeneration via paracrine mechanisms, which remain to be elucidated. Here, we show physiologically quiescent SM22α-lineage expand after injury regulate diverse processes of intramembranous The majority neither act as stem in vivo nor their expression patterns. Dysfunction induced by loss platelet-derived growth factor receptor β (PDGFRβ) impairs repair. We further...
Aim:To obtain the distribution of different maxilla-mandibular characteristics in Chinese skeletal class II mixed dentition patients and to compare differences cephalometric variables among types. Materials methods:A cross-sectional study was conducted 310 dentition.The were divided into 6 groups according SNA SNB angle cephalogram.A total 38 measurements measured on their cephalograms.Differences tested by one-way analysis variance.Results: There 34 (10.97%)patients group I, 10 (3.23%) II,...
Abstract Objective To figure out whether premolar extractions treatment would influence the cant of occlusal planes and thus affect dentoskeletal patterns in patients with different types malocclusions. Materials Methods A total 140 post‐orthodontic subjects (96 females, 44 males) were included this study, their lateral cephalograms demographic information collected analysed. The divided into extraction non‐extraction groups. ANB, SNA, SNB, Wits, Facial Height Index (FHI), SN‐MP, SN‐AOP,...
Objective: to explore the association between distance of disc displacement and morphology in patients with temporomandibular disorders (TMDs). Methods: a total 717 joints 473 subjects were enrolled this cross-sectional study. The magnetic resonance imaging (MRI) each patient was evaluated for joint (TMJ) classification position. length measured smoothing spline prediction. A stratified analysis performed based on types positions. width length-width ratio (L/W) also measured. Descriptive...
Abstract Background Confronting with the outbreak of COVID-19, this cross-sectional study aimed to assess differences psychological status temporomandibular disorders patients, orthodontic patients and general population in China during epidemic. Methods An online anonymous questionnaire was developed Chinese, including individual background information, perception epidemic, level anxiety depression through Kessler Psychological Distress Scale (K10). The respondents were divided into Control...
Dental implant is a commonly used therapeutic option for reconstruction of edentulous space. Adequate peri-implant soft tissue crucial preventing biological and esthetic complications. Peri-implant soft-tissue phenotypes including supracrestal height, mucosa thickness keratinized width could reflect the quality quantity tissue. Different might impact stability restoration through altering remodeling or inflammatory response. This review will discuss influence on response after placement.
Objective: To investigate the relationship between pattern recognition receptor triggering receptors expressed on myeloid cells-1 (TREM-1) and M1/M2 polarization in macrophages stimulated by Porphyromonas gingivalis lipopolysaccharide (Pg-LPS), so as to explore mechanism of TREM-1 periodontitis. Methods: Human monocytic cell line THP-1 were induced differentiate into phorbol-12-myristate-13-acetate 0 (blank control group) 1 μg/ml Pg-LPS (LPS group), respectively. LP17, inhibitor (LPS+LP17...
Objective: To illuminate the temporal expression of triggering receptor expressed on myeloid cells-1 (TREM-1) in experimental periodontitis rat and to investigate function TREM-1 pathogenesis rat. Methods: The model was established maxillary first molar by means 'wire ligation + vaccination periodontal pathogen Porphyromanus gingivalis (Pg) high-sugar diet' Sprague-Dawley (SD) rats. animals were divided into six groups: control group each time points establishing models for one week two five...
Objective: To investigate craniofacial differences in individuals with hypodontia and explore the relationship between features number of congenitally missing teeth.Methods: A cross-sectional study was conducted among 261 Chinese patients (males, 124; females, 137; age, 7-24 years), divided into four groups (without hypodontia: no teeth missing, mild: one or two teeth, moderate: three to five severe: six more teeth) according teeth.Differences cephalometric measurements were...