- Parasitic Infections and Diagnostics
- Toxoplasma gondii Research Studies
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Liver Disease Diagnosis and Treatment
- Coccidia and coccidiosis research
- MicroRNA in disease regulation
- Sleep and related disorders
- Amoebic Infections and Treatments
- Influenza Virus Research Studies
- Pharmacological Receptor Mechanisms and Effects
- Acupuncture Treatment Research Studies
- Birth, Development, and Health
- Cancer, Lipids, and Metabolism
- Cytomegalovirus and herpesvirus research
- RNA modifications and cancer
- Sleep and Wakefulness Research
- Microbial infections and disease research
- Helminth infection and control
- Rabies epidemiology and control
- Chronic Myeloid Leukemia Treatments
- Child Abuse and Related Trauma
- Veterinary medicine and infectious diseases
- Tuberculosis Research and Epidemiology
- Saffron Plant Research Studies
Jiangsu Province Hospital
2021-2025
Changchun University
2019-2025
Nanjing University of Chinese Medicine
2019-2025
Heilongjiang University of Chinese Medicine
2025
Sichuan University
2016-2023
West China Hospital of Sichuan University
2016-2023
Suzhou Polytechnic Institute of Agriculture
2023
Chengdu Third People's Hospital
2023
Southwest Jiaotong University
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2019-2023
To examine the prevalence of E. bieneusi and Blastocystis sp. in foxes China, this study analyzed distribution genotypes or subtypes. A total 352 fresh fecal samples were collected from across five provinces northern China using PCR. The overall prevalences 48.3% 2.0%, respectively; highest found Shandong Province, with 87.1% 5.4%, respectively. rates influenced by several factors; a breeding scale value <1,500 was related to higher prevalences. Multivariate analysis showed that region...
Abstract In this study, a lipid disorder Alzheimer’s disease (AD) model was developed with high-fat diet and d -galactose injected intraperitoneally (HFD & -gal) to evaluate the activities of Buyang Huanwu Decoction (BYHWD) compared donepezil hydrochloride. The learning memory abilities BYHWD were evaluated by Morris water maze test (MWM). levels in serum, histopathology, immunohistochemistry hyperphosphorylated tau protein hippocampal neurons conducted prove therapy effects BYHWD. After...
Background: As a natural accelerator of highly pathogenic avian influenza in wild birds, the H9 subtype poses substantial threat to both humans and poultry industry. A comprehensive meta-analysis is necessary assess current status global outbreak. In this research, literature review are presented on surveillance studies birds worldwide up 2024. Methods: search strategy was employed, utilizing China Science Technology Journal Database, National Knowledge Infrastructure, PubMed, Google...
There reportedly exists a significant comorbidity between insomnia and neurodegenerative diseases, such as Alzheimer's disease (AD) Parkinson's (PD), indicative of potential link to serum metabolic dysregulation. To elucidate shared pathophysiological mechanisms AD/PD, we performed comprehensive two-sample Mendelian randomization (MR) analyses, investigating 1,400 characteristics for their causal relationships with the risks insomnia, AD, widely defined AD (WDAD), PD. We employed publicly...
The impacts of environmental chemicals on the decline kidney function have been suggested by a limited number statistical and animal studies. Thus, those exposures may be modifiable risk factors for chronic disease. Some chemicals, such as Perfluoroalkyl acid (PFA), are pervasive throughout our environment, determining their health effects is an important public concern. In this study, we examined cross-sectional data from 2009-2010 cycle National Health Nutrition Examination Survey (NHANES)...
Purpose: Nonalcoholic fatty liver disease (NAFLD) is closely related to lipid metabolism and insulin resistance. The current research mainly attempted verify the clinical value of LncRNA plasmacytoma variant translocation 1 (PVT1), whether microRNA regulates resistance participate in NAFLD. Patients Methods: 81 patients with NAFLD 78 healthy individuals were enrolled this study. In addition, C57BL/6 mice fed a high-fat diet establish model vivo. Serum PVT1 miR-20a-5p expression assessed by...
Rationale: The presence of the Philadelphia chromosome (Ph) in acute lymphoblastic leukemia (ALL) has been associated with a high risk disease relapse and poor prognosis. Allogeneic hematopoietic stem cell transplantation (HSCT) is an established treatment for adults Ph-positive ALL, but remains primary cause failure, extremely emergence resistance to tyrosine kinase inhibitors (TKIs) poses challenge patients relapses after initial TKI-containing regimens. Patient concerns: Two TKI-resistant...
Giardia duodenalis is one of the most important intestinal parasites that can infect virtually all animals, including rabbits and humans. However, there little information regarding prevalence genotypes G. in domestic China.A total 426 rabbit fecal samples (136 from Shenyang City, 174 Changchun 116 Jilin City) were examined by Lugol's iodine staining with microscopy analysis, positive genotyped at triosephosphate isomerase (tpi) beta giardin (bg) gene loci using nested PCR.Forty-two (9.86%)...
Enterocytozoon bieneusi , a zoonotic pathogen prevalent in both humans and animals, is the most frequently diagnosed microsporidian species presents significant public health risks. However, data on prevalence genotypes of E. farmed minks ( Neovison vison ) raccoon dogs Nyctereutes procyonoides China are limited. Therefore, 275 (89 from Hebei Province, 57 Heilongjiang 109 Liaoning 20 Shandong Province) 235 (114 27 61 33 Jilin were examined for through sequence analysis internal transcribed...
A series of novel tricyclic matrinic derivatives with 11-adamantyl substitution were designed, synthesized, and evaluated for their activities against Influenza H3N2 virus, based on the privileged structure strategy. Structure-activity relationship (SAR) analysis indicated that introduction an might be helpful potency. Among them, compounds 9f 9j exhibited promising anti-H3N2 IC50 values 7.2 μM 10.2 μM, respectively, better than lead 1. Their further confirmed at protein level. Moreover,...
Toxoplasma gondii and Chlamydia are common protozoan pathogens, which can pose health risks to people around the world cause considerable economic losses. Although information on seroprevalence of T. in chickens be found China, knowledge infection these two diseases rural chickens, ducks, geese is limited. Therefore, blood samples from 377 268 379 were taken areas seven cities northeastern their seropositivity was analyzed by indirect hemagglutination antibody (IHA) test with a cutoff titer...