Muhammad Aslam

ORCID: 0000-0003-3208-9858
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About
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Research Areas
  • Reproductive Physiology in Livestock
  • Sperm and Testicular Function
  • Genetic and phenotypic traits in livestock
  • Multiple Myeloma Research and Treatments
  • Reproductive Biology and Fertility
  • Protein Degradation and Inhibitors
  • Livestock Management and Performance Improvement
  • Peptidase Inhibition and Analysis
  • Effects of Environmental Stressors on Livestock
  • Herpesvirus Infections and Treatments
  • Poxvirus research and outbreaks
  • Cancer Treatment and Pharmacology
  • Agricultural Systems and Practices
  • Bacillus and Francisella bacterial research
  • Animal Genetics and Reproduction
  • Child Development and Digital Technology
  • Ruminant Nutrition and Digestive Physiology
  • Molecular Biology Techniques and Applications
  • Agricultural Economics and Practices
  • Biological Control of Invasive Species
  • Silkworms and Sericulture Research
  • Insurance, Mortality, Demography, Risk Management
  • Reproductive biology and impacts on aquatic species
  • Aldose Reductase and Taurine
  • IgG4-Related and Inflammatory Diseases

University of Faisalabad
2017-2025

Saskatchewan Cancer Agency
2022-2024

Kerala Veterinary and Animal Sciences University
2022

National Dairy Research Institute
2014-2021

Cancer Council SA
2020

Wordsley Hospital
2007

King Faisal Specialist Hospital & Research Centre
1997

The resurgence of the disease in humans that is very similar to smallpox called monkeypox (MPX) disease, caused by virus (MPXV), dominant topic discussion scientific and popular press around world right now. This taking place as celebrates historic accomplishments made fight against Coronavirus Disease (COVID-19) pandemic MPX currently thought pose a risk general public's health, particularly areas with high rates MPXV infection close human-wild animal contact. Despite rarity outbreaks, they...

10.18006/2022.10(4).679.688 article EN Journal of Experimental Biology and Agricultural Sciences 2022-08-30

Contents The present study identified few potential proteins in the spermatozoa of buffalo bulls that can be used as an aid fertility determination through comparative proteomics. sperm proteome high‐fertile was compared with low‐fertile using two‐dimensional difference gel electrophoresis (2D‐DIGE), and differentially expressed were mass spectrometric method. protein interaction network functional bioinformatics analysis also carried out. In bulls, 10 found overexpressed 15 underexpressed...

10.1111/rda.13426 article EN Reproduction in Domestic Animals 2019-03-01

It can be said that the effects of YouTube Kids as an educational tool on children's comprehension and retention scientific concepts are evaluated. As digital media continues to used increasingly for early education, this research explores what extent content accessibility, design interactivity impact learning outcomes children aged 6-10. Pre post tests were combined with focus group discussions where participants discussed they understood remembered in had been exposed after being curated...

10.71317/rjsa.003.01.0071 article EN cc-by 2025-01-30

The research examines the influence of YouTube Kids on science learning motivation among elementary school students by employing a quantitative survey-based methodology. Participants were divided into two groups: an experimental group (n=20), which engaged with curated videos Kids, and control received traditional classroom instruction. Data collected exclusively through validated 29-item Likert-scale questionnaire measuring students' interest in topics, inquiry inclination, science-related...

10.62345/jads.2025.14.1.74 article EN Deleted Journal 2025-03-01

Sub-fertility is one of the most common problems observed in crossbred males, but etiology remains unknown cases. Although proteomic differences spermatozoa and seminal plasma between breeds have been investigated, possible at sperm precursor cells supporting/nourishing not studied. The present study reports differential profile spermatogenic Sertoli purebred bulls. Testis was removed by unilateral castration 12 peri-pubertal bulls (10 months age), four each from (Holstein Friesian ×...

10.3389/fcell.2014.00024 article EN cc-by Frontiers in Cell and Developmental Biology 2014-06-04

Present study analyzed the changes in peripheral blood testosterone concentrations and testicular cytogram relation to age semen quality crossbred males. Three different groups of males viz. bull calves (6 months, n = 5), young bulls (15 5) adult (4 6 years, 8) were utilized for study. Testicular fine needle aspiration cytology technique was used quantify their indices. Peripheral measured using enzyme-linked immunosorbent assay method. Semen samples collected from microscopically evaluated...

10.5713/ajas.2014.14139 article EN cc-by Asian-Australasian Journal of Animal Sciences 2014-10-16

The present study compared the testicular cytology and histology between crossbred (Holstein-Friesian [HF] × Tharparkar) purebred (HF bulls to find out differences if any.Four peripubertal from each breed were utilized for study. Through percutaneous needle aspiration biopsy, Sertoli spermatogenic cells extracted, morphometry was studied. For histological studies, tissues obtained through unilateral castration utilized. specific GATA4 antibody used population of in seminiferous tubule...

10.14202/vetworld.2015.645-650 article EN cc-by Veterinary World 2015-05-01

Abstract Multiple myeloma (MM) remains incurable despite the availability of novel agents. This multi-center retrospective cohort study used Canadian Myeloma Research Group Database to describe real-world outcomes patients withanti-CD38 monoclonal antibody (mAb) refractory MM subsequently treated with standard care (SoC) regimens. Patients triple class (TCR) disease (refractory a proteasome inhibitor, immunomodulatory drug, and anti-CD38 mAb) were examined as distinct cohort. Overall, 663...

10.1038/s41408-023-00946-z article EN cc-by Blood Cancer Journal 2023-12-08

The present study analyzed the relationship between testicular biometry and initial semen quality in Karan Fries (KF) crossbred bulls. Data on production traits of KF bulls (n=32) spread over a period 3 years were to find out ejaculate rejection rate (ERR). scrotal circumference (SC), length (TL) width (TW) measured once month 16 ejaculates collected from (n=24). different measurements was studied. To if parameters differ good poor producing bulls, based evaluation, ranked into poor. Our...

10.56093/ijans.v84i2.37848 article EN cc-by-nc-sa The Indian Journal of Animal Sciences 2014-02-12

Male fertility is extremely important in dairy animals because semen from a single bull used to inseminate several thousand females. Asthenozoospermia (reduced sperm motility) and oligozoospermia concentration) are the two reasons cited for idiopathic infertility crossbred bulls; however, etiology remains elusive. In this study, using non-targeted liquid chromatography with tandem mass spectrometry-based approach, we carried out deep metabolomic analysis of spermatozoa seminal plasma derived...

10.3389/fvets.2021.755560 article EN cc-by Frontiers in Veterinary Science 2022-01-11

The fundamental aim of silkworm breeding is to get robust and sturdy larvae for easy rearing production best cocoons in quality quantity a high yielding cocoon crop. In Pakistan, efforts are being made continuously give boost the sericulture industry by developing pure parental lines suitable commercial purposes. study was carried out evaluate genetic potential eleven (PAK-1, PAK-2, PAK-3, PAK-4, M-101, M-103, M-104, M-107, S-1, PFI-1 PFI-2) during 2006 - 2008 at Sericulture Research...

10.5897/ajfs.9000127 article EN African Journal of Food Science 2010-05-31

Recent cases of monkeypox (MPX), a zoonotic illness caused by virus (MPXV), outside Africa have prompted international public health concerns. The emergence, re-emergence, and global dispersion zoonoses are profoundly impacted wide variety causes, including but not limited to climate change, urbanization, animal migration, quick means travel tourism, vector biology, anthropogenic influences, natural factors. Human MPX was first identified in the Democratic Republic Congo (DRC) 1970, since...

10.22207/jpam.16.spl1.11 article EN cc-by Journal of Pure and Applied Microbiology 2022-12-29

Summary Daratumumab (dara) has significantly altered the therapeutic landscape of multiple myeloma (MM), especially in relapsed setting. This study aimed to evaluate outcomes dara‐containing regimens Canadian real‐world setting among and refractory MM available within national Myeloma Research Group Database (CMRG‐DB). A total 583 patients who received dara‐based therapy second‐line or later treatment were included. After a median follow‐up 17.5 months, progression‐free survival (PFS)...

10.1111/bjh.18172 article EN British Journal of Haematology 2022-04-05

A study was conducted on calving records of Murrah buffaloes to the influence various functional traits subsequent reproductive performance. The effects abnormalities, uterine health problems, female fertility problems and udder problem first service (CFS), period (SP), dry (DP) interval (CI) were studied by least-squares method using SAS package. increase in CFS, SP, DP CI 27.07%, 18.71%, 96.74% 6.70%, respectively. Subsequently, average milk yield per day found be reduced (from 4.91 2.10...

10.1080/09712119.2015.1102727 article EN Journal of Applied Animal Research 2015-11-01

Although daratumumab-containing regimens improve multiple myeloma (MM) outcomes, recurrence is inevitable.We performed a retrospective study using the Canadian Myeloma Research Group Database to benchmark efficacy of carfilzomib- or pomalidomide-based therapies immediately following progression on daratumumab treatment.We identified 178 such patients; median number prior lines therapy was 3, 97% triple-class exposed, and 60% refractory. In our cohort, 75 received subsequent carfilzomib-based...

10.1111/ejh.14082 article EN European Journal Of Haematology 2023-08-13

Abstract Carfilzomib is an active and commonly used treatment in patients with multiple myeloma (MM). Using the Canadian Myeloma Research Group Database, we performed a retrospective observational study of treated carfilzomib for relapse MM real‐world setting Canada between years 2007 2020. A total 445 were included this study: doublet (Kd/p, n = 218) triplets (KCd, 88; KRd, 99; KPd/p, 40). One hundred twenty‐two (27%) received carfilzomib‐based line 2, 133 (30%) 3, 90 (20%) 4, 100 (23%) 5...

10.1002/jha2.559 article EN cc-by eJHaem 2022-08-31

Monkeypox (MPX) is a zoonotic disease that endemic to the western and central regions of Africa it caused by monkeypox virus (MPXV), which classified as member Poxviridae family, specifically Chordopoxvirinae subfamily, Orthopoxvirus genus. The current multiregional outbreak MPX, started in May 2022, has since swiftly spread across globe thus been declared global public health emergency World Health Organization (WHO). Protective immunity against MPXV can be achieved administering smallpox...

10.22207/jpam.16.spl1.08 article EN cc-by Journal of Pure and Applied Microbiology 2022-12-29
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