A5048203758- Animal Genetics and Reproduction
- Reproductive Biology and Fertility
- Genetic and phenotypic traits in livestock
- Reproductive Physiology in Livestock
- Milk Quality and Mastitis in Dairy Cows
- Effects of Environmental Stressors on Livestock
- Probiotics and Fermented Foods
- Sperm and Testicular Function
- Protein Hydrolysis and Bioactive Peptides
- CRISPR and Genetic Engineering
- Cancer-related molecular mechanisms research
- interferon and immune responses
- Chromosomal and Genetic Variations
- Heat shock proteins research
- Immune Response and Inflammation
- Ovarian function and disorders
- Antimicrobial Peptides and Activities
- Genetic Mapping and Diversity in Plants and Animals
- Molecular Biology Techniques and Applications
- Bacteriophages and microbial interactions
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Renal and related cancers
- Microbial infections and disease research
- Animal Disease Management and Epidemiology
- Reproductive System and Pregnancy
National Dairy Research Institute
2015-2024
Indian Council of Agricultural Research
2022-2023
Indian Veterinary Research Institute
2013-2023
Central Institute for Research on Goats
2022
Central Sheep and Wool Research Institute
2021
ICAR Research Complex for NEH Region
2018
National Bureau of Animal Genetic Resources
2012-2014
Odisha University of Agriculture and Technology
2013
Uppsala University
2009
Yasuj University of Medical Sciences
2006
This study identifies a previously uncharacterized protein, encoded by domesticated DNA transposon, called ZBED6 that regulates the expression of insulin-like growth factor 2 (IGF2) gene, and possibly numerous others, in all placental mammals including human.
Heat shock protein 70 (HSP70) is one of the most abundant and best characterized heat family that consists highly conserved stress proteins, expressed in response to stress, plays crucial roles environmental tolerance adaptation. The present study was conducted identify major types genes under HSP70 quantify their expression pattern heat- cold-adapted Indian goats (Capra hircus) with respect different seasons. Five gene homologues HSPA8, HSPA6, HSPA1A, HSPA1L, HSPA2 were identified by...
To explore the heat and cold adaptation in Indian goats by physiological, haematological, blood biochemical parameters their seasonal variations, this study was conducted on heat- cold-adapted maintained natural habitat. Study carried out three different phases coincide with seasons (winter, spring summer). The levels of physiological responses, that is rectal temperature, respiration rate pulse rate, were observed to be significantly (p < 0.01) lower heat-adapted breeds higher breeds,...
The anticarcinogenic effect of aqueous extract fruit Momordica charantia (bitter gourd), which is widely used as a vegetable in India, was studied two-step skin carcinogenesis model mice. possible mode action also investigated. Oral administration the found to have an adverse on general health and lifespan animals when at high concentration. But this dose reduced by half, test afforded protection from development tumour increased life expectancy. Carcinogen-induced lipid peroxidation liver...
The effect of dietary supplementation milk fermented with indigenous probiotic Lactobacillus plantarum (LP625) alone and in combination herbs ( Aloe vera Gymnema sylvestre ) was investigated on high fat diet (HFD, 60 kcal% fat) fed mice for 12 weeks. Administration LP625 or both lowered the final body weight, however, a significant difference observed supplemented only as compared to HFD group (25.06±0.18 vs 27.29±0.72 g, P <0.05). Similarly, epididymal mass, fasting blood glucose serum...
The present study was designed for screening polymorphism of known fecundity genes in prolific Indian Bonpala sheep. Employing tetra-primer amplification refractory mutation system PCR, 11-point mutations BMP1B, BMP15, and GDF9 97 ewes were genotyped. FecB locus the BMPR1B gene two loci (G1 G4) found to be polymorphic. In locus, three genotypes, namely, wild type (Fec++, 0.02), heterozygous (FecB+, 0.23), mutant (FecBB, 0.75) detected. At G1 gene, (GG, 0.89), (GA, 0.10), (AA, 0.01) G4 0.01),...
Nucleotide binding and oligomerization domain (NOD2) is a key component of innate immunity that highly specific for muramyl dipeptide (MDP)-a peptidoglycan bacterial cell wall. MDP recognition by NOD2-leucine rich repeat (LRR) activates NF-κB signaling through protein-protein interaction between caspase activating recruitment domains (CARDs) NOD2 downstream receptor interacting protein kinase 2 (RIP2). Due to the lack crystal/NMR structures, CARD-CARD are poorly understood. Herein, we have...
Cathelicidins are an ancient class of antimicrobial peptides (AMPs) with broad spectrum bactericidal activities. In this study, we investigated the diversity and biological activity cathelicidins buffalo, a species known for its disease resistance. A series new homologs cathelicidin4 (CATHL4), which were structurally diverse in their domain, was identified buffalo. AMPs newly buffalo CATHL4s (buCATHL4s) displayed potent against selected Gram positive (G+) negative (G-) bacteria. These prompt...
Nowadays, studies about the anti‐obesity potential of probiotics are growing interest. Lactobacilli one well‐studied owing to their preventing effect on metabolic disorders. This study was undertaken access probiotic dahi containing Lactobacillus casei NCDC 19 C57 BL /6 mice. Feeding showed reduce body weight gain and epididymal fat weights. Moreover, blood glucose, plasma lipids expression level leptin were reduced caecal bifidobacteria counts adiponectin levels significantly increased. It...
Riboflavin has an important role in various cellular metabolic activities through its participation oxidation-reduction reactions. In this study, as many 60 lactobacilli were screened for the presence or absence of riboflavin biosynthesis genes and production. Of these, only 14 strains able to grow a commercial riboflavin-free medium. We observed that is strain-specific across different species lactobacilli. The microbiological assay was found be appreciably reproducible, sensitive, rapid,...
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs), the first line of defense, are cytosolic pattern recognition (PRRs) that regulate inflammatory activity in response to invading pathogens. NLRs members AAA+ ATPase superfamily comprises N-terminal EBD(s), a centrally positioned NOD/NACHT varying range LRRs towards C-terminal end. Due lack structural data, functional aspects NLRP-signaling mechanism, which includes pathogen recognition, nucleotide-binding,...