A5084941751- Neural and Behavioral Psychology Studies
- Neural dynamics and brain function
- EEG and Brain-Computer Interfaces
- Action Observation and Synchronization
- Memory and Neural Mechanisms
- Vestibular and auditory disorders
- Visual perception and processing mechanisms
- Neurobiology of Language and Bilingualism
- Motor Control and Adaptation
- Psychology of Moral and Emotional Judgment
- Functional Brain Connectivity Studies
- Sleep and Wakefulness Research
- Attention Deficit Hyperactivity Disorder
- Stress Responses and Cortisol
- Neuroscience and Music Perception
- Language, Metaphor, and Cognition
- Multisensory perception and integration
- Child and Animal Learning Development
- Memory Processes and Influences
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Sleep and related disorders
- Ophthalmology and Eye Disorders
- Neurotransmitter Receptor Influence on Behavior
- Linguistic Education and Pedagogy
- Behavioral and Psychological Studies
Heinrich Heine University Düsseldorf
2015-2024
Ruhr University Bochum
2007-2016
Freie Universität Berlin
2013
Abstract The feedback‐related negativity (FRN) has been hypothesized to be linked reward‐based learning. While many studies have shown that the FRN only occurs in response unexpected negative outcomes, relationship between magnitude of prediction errors and amplitude remains a matter debate. present study aimed elucidate this with new behavioural procedure allowed subjects predict precise reward probabilities by learning an explicit rule. Insight into rule did not influence subjects' choice...
Summary The aim of the investigations was to explore nature and severity cognitive deficits in narcolepsy patients. In two studies, patients were compared with matched control subjects on a range attention, memory executive tasks. Impairments only observed attention function tasks which involved higher demands inhibition or task management abilities whereas relatively routine yielded intact performance overall pattern results indicates an deficit might be related reduction available...
Performance feedback during learning is accompanied by a negative event-related potentials (ERP) component, the feedback-related negativity (FRN), which codes reward prediction error. An open issue relates to coding of stimuli in observational learning. The present study aimed determine differences neural processing active and learners between-subjects design. By choosing between different stimuli, 15 could learn rule determining probability monetary reward. Each observers was yoked...
Abstract The present study investigated temporal aspects of cerebellar contributions to the processing performance errors as indexed by error-related negativity (ERN) in response-locked event-related potential (ERP). We co-registered EEG and applied single-pulse transcranial magnetic stimulation (spTMS) left posterolateral cerebellum an extra-cerebellar control region (vertex) while healthy adult volunteers performed a Go/Nogo Flanker Task. In Go trials, TMS pulses were at four different...
Corollary discharge signals play an important role in monitoring self-generated movements to guarantee spatial constancy. Recent work macaques suggests that the thalamus conveys corollary information of upcoming saccades passing from superior colliculus frontal eye field. The present study aimed investigate involvement humans by assessing effect thalamic lesions on processing information. Thirteen patients with selective and 13 healthy age-matched control subjects performed a saccadic...
The basal ganglia (BG) are thought to play a key role in learning from feedback, with mesencephalic dopamine neurons coding errors reward prediction, thereby mediating information processing the BG and prefrontal cortex. In present study, reward-based was assessed patients focal lesions, by studying outcome-based acquisition reversal of stimulus-stimulus associations different magnitudes two probabilistic tasks. Eleven selective lesions (three females) 18 healthy control subjects (six...
Reward-based associative learning is mediated by a distributed network of brain regions that are dependent on the dopaminergic system. Age-related changes in key this system, striatum and prefrontal cortex, may adversely affect ability to use reward information for guidance behavior. The present study investigated effects healthy aging different components learning, such as acquisition, reversal, magnitude, transfer learning. A group 30 young (mean age = 24.2 yr) older subjects 64.1...
Recent rodent data suggest that the cerebellum – a region typically associated with processing sensory prediction errors (PEs) also processes PEs in reinforcement learning (RL-PEs; i.e., from action outcomes). We tested whether cerebellar output is necessary for RL-PE regions more traditionally action-outcome processing, such as striatum and anterior cingulate cortex. The feedback-related negativity (FRN) was measured proxy of cerebral probabilistic feedback task using...
To survive and thrive in our ever-changing environment, we need to be able predict the consequences of actions. We update these predictions by learning through trial error, associated prediction errors (PEs). Recent rodent data suggest that cerebellum – a region typically with processing sensory PEs supervised error-based also processes reinforcement (RL-PEs; i.e., from action outcomes). A proxy outcome regions traditionally RL-PE coding, such as striatum anterior cingulate cortex, can...
ABSTRACT Patients treated with microsurgical clipping of ruptured intracranial aneurysms often suffer from neuropsychological deficits in spite a good neurological outcome. The purpose this study was to explore if the are related type therapy. Two groups 16 patients each suffering aneurysmal SAH, matched for sex, age, aneurysm-site and Hunt Hess score, control subjects were examined battery tests including memory, attention, executive function. Depression, mood, quality life also assessed....
Event-related potentials (ERP) research has identified a negative deflection within about 100 to 150 ms after an erroneous response – the error-related negativity (ERN) - as correlate of awareness-independent error processing. The short latency suggests internal monitoring system acting rapidly based on central information such efference copy signal. Studies monkeys and humans have thalamus important relay station for signals ongoing saccades. present study investigated processing...
Tool stimuli can be analyzed based on their affordance, that is, visual structure hinting at possible interaction points. Additionally, familiar tools initiate the retrieval of stored object-action associations, providing basis for a meaningful object use. The mu rhythm within electroencephalographic alpha band is associated with sensory-motor processing and was shown to modulated during sight tool stimuli, suggesting motor cortex activation either affordance or access conceptual...
Abstract Processing of performance‐related feedback is an essential prerequisite for adaptive behavior. Even though in everyday life rarely immediate, to date very few studies have investigated whether the feedback‐related negativity (FRN), a relative ERP approximately 200 300 ms after that sensitive valence and predictability, modulated by timing, findings are inconsistent. The present study effects gradually increasing delays on processing FRN time window. Subjects completed probabilistic...
Learning from feedback is a prerequisite for adapting to the environment. Prediction error signals coded by midbrain dopamine (DA) neurons are projected basal ganglia and anterior cingulate cortex (ACC). It has been suggested that neuronal activity shifts away DA system when delayed. The feedback-related negativity (FRN), an ERP generated in ACC shown be sensitive valence prediction magnitude, was found reduced delayed feedback. has, however, not yet investigated if FRN reflects reward...
Recent models assume that some symptoms of schizophrenia originate from defective reward processing mechanisms. Understanding the precise nature reward-based learning impairments might thus make an important contribution to understanding and development treatment strategies. The present study investigated several features probabilistic stimulus association learning, namely acquisition initial contingencies, reversal generalization abilities, effects magnitude. Compared healthy controls,...
Abstract Humans can adapt their behavior by learning from the consequences of own actions or observing others. Gradual active action–outcome contingencies is accompanied a shift feedback- to response-based performance monitoring. This reflected complementary learning-related changes two ACC-driven ERP components, feedback-related negativity (FRN) and error-related (ERN), which have both been suggested signal events “worse than expected,” that is, negative prediction error. Although recent...