Takeshi Osawa

ORCID: 0000-0003-3213-3302
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Research Areas
  • Reproductive Physiology in Livestock
  • Genetic and phenotypic traits in livestock
  • Effects of Environmental Stressors on Livestock
  • Reproductive Biology and Fertility
  • Ruminant Nutrition and Digestive Physiology
  • Animal health and immunology
  • Sperm and Testicular Function
  • Reproductive System and Pregnancy
  • Vector-Borne Animal Diseases
  • Veterinary Equine Medical Research
  • Epilepsy research and treatment
  • Microbial infections and disease research
  • Animal Disease Management and Epidemiology
  • Neuroscience and Neuropharmacology Research
  • Ovarian cancer diagnosis and treatment
  • Growth Hormone and Insulin-like Growth Factors
  • Ovarian function and disorders
  • Toxoplasma gondii Research Studies
  • Testicular diseases and treatments
  • Biochemical effects in animals
  • Proteoglycans and glycosaminoglycans research
  • Skin and Cellular Biology Research
  • Animal Behavior and Welfare Studies
  • Herpesvirus Infections and Treatments
  • T-cell and Retrovirus Studies

University of Miyazaki
2016-2025

Tokyo Metropolitan University
2023

Teikyo University Hospital
2023

Iwate University
2006-2016

Gifu University
2006-2012

Izumi City General Hospital
2012

Kanazawa University
2008

Iwate Medical University
1990-2002

Moredun Research Institute
1998-2002

Rakuno Gakuen University
1995-1998

Daily electrical stimulation of the amygdala in Senegalese baboons (Papio papio) resulted development generalized convulsive seizures focal onset through five distinct clinical stages an average 72 days. The chronologic pattern electroclinical features suggested that vertical intrahemispheric ictal dissemination was primary importance progressive seizure development. Some animals developed spontaneous recurrence both partial complex and seizures. kindling preparation P. papio represents a...

10.1212/wnl.26.3.273 article EN Neurology 1976-03-01

Amygdaloid kindling in rhesus monkeys resulted development of secondarily generalized convulsive seizures an average 196 days. Prior pharmacologic (bemegride) accelerated this seizure one animal. None the animals reached stage 5 primary baboons (Papio papio), even after 400 daily amygdaloid stimulations. Seizure instability, with frequent regression to earlier stage, and difficulty establishing a triggering threshold most monkeys, contrasts our experiences Papio papio. Thus, differences...

10.1212/wnl.28.10.1026 article EN Neurology 1978-10-01

SUMMARY: In our earlier study of amygdaloid kindling in Papio papio (Pp), the development partial complex seizure and focal motor was correlated with bifrontal theta discharge increasing Rolandic spike respectively final stage characterized by primary generalized convulsive seizure. Since latter pattern is known to originate from frontal focus man, cortex became suspect pattern. Daily prefrontal stimulation showed that Pp can be kindled this site, culminating a recurrent spontaneous state...

10.1017/s031716710002062x article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 1975-11-01

We investigated the relationship between persistence of uterine bacterial infections with cytologically determined endometritis and ovarian function in 65 postpartum Holstein cows. Vaginal mucus discharges were collected, endometrial smear samples (n = 130) collected for cytological bacteriological examinations from cows at weeks 5 7 (pp). Blood 3, pp to determine plasma progesterone concentrations monitor activity. According examination, classified into four groups. The first group 32; 49%)...

10.1262/jrd.2014-051 article EN cc-by-nc-nd Journal of Reproduction and Development 2014-12-05

SUMMARY This preliminary study utilizing the kindling model of established epilepsy has provided information about most effective routes administration for diphenylhydantoin, phenobarbital, and carbamazepine in baboons cats. The time peak plasma levels these drugs been demonstrated animals so that experimental protocols can be designed to deliver agents at appropriate times prior stimulation. In addition, dose‐effectiveness data is presented species. 1 baboon, phenobarbital was also seen...

10.1111/j.1528-1157.1976.tb03386.x article EN Epilepsia 1976-03-01

SUMMARY Intraperitoneal injections of delta 8‐tetrahy‐drocannabinol (THC) and 9‐THC failed to affect myoclonic response photic stimulation in Senegalese baboons (Papio papio). However. both isomers THC exerted dose‐related antiepileptic effects upon established kindled convulsions provoked by electrical amygdala the same species. Delta was more potent than 8‐THC, terms general toxicity. The appear be due mainly suppression propagation induced afterdischarge distant cérébral structures,...

10.1111/j.1528-1157.1975.tb06071.x article FR Epilepsia 1975-09-01

Contents Seventy pluriparous high‐yielding cows were used to investigate the impact of metabolic traits and body condition score (BCS) during early lactation on subclinical endometritis diagnosed at weeks 5, 6 7 postpartum (pp). Blood samples collected from animals with no peripartum problems second (W2) seventh (W7) pp estimate some blood metabolites including non‐esterified fatty acids (NEFA), β‐hydroxybutyric acid (BHBA), glucose, total cholesterol (T‐chol) urea nitrogen (BUN)....

10.1111/j.1439-0531.2011.01941.x article EN Reproduction in Domestic Animals 2011-11-07

The current study aimed to define the plasma profile of anti-Müllerian hormone (AMH) and follicle stimulating (FSH) in heifers during postnatal life until achieving puberty, as defined by progesterone (P4) profile, demonstrate a relationship between AMH age puberty onset. Blood samples collected from 11 Japanese Black female calves within 1 week after birth (W 0) then biweekly sixth (WP 6) were assayed for AMH, FSH, P4. classified into two groups based on onset: ≤42 weeks (early group; EP, n...

10.1093/biolre/iox069 article EN Biology of Reproduction 2017-06-30

Endometritis is one of the major diseases causing infertility in cow. Intrauterine infusion povidone-iodine (PVP-I) a common treatment. However, optimal concentration PVP-I for treating endometritis effectively remains unknown. We tested concentrations 2.0% or 0.5% clinical dairy cattle. In Experiment 1, bacteria isolated from uterus were incubated with either PVP-I, and numbers bacterial colonies counted. 2, 18 cows treated (n=9 each group). Cytology samples collected using cytobrush on...

10.1292/jvms.15-0412 article EN Journal of Veterinary Medical Science 2015-12-10

A certain level of endometrial bacterial infection and inflammation is involved in bovine uterine involution during the puerperal period. Factors that hamper normal expose environment to pathological conditions, causing different endometritis levels. The lack proper diagnostic tools extends time conception. Efforts have been made elucidate postpartum environment, including flora, changes transient inflammation, pathophysiology endometritis, improve reproductive performance. E. coli...

10.1262/jrd.2021-052 article EN cc-by-nc-nd Journal of Reproduction and Development 2021-01-01

The calving interval (CI) is an important determinant of reproductive performance in Japanese Black cattle. present study aimed to compare individual fertility traits among farms classified by CI. In total, 49,780 artificial insemination (AI) records for 7327 cows from 2011 2014 were obtained 622 located Miyazaki, Japan. into three groups (referred as farm CI groups) using the lower and upper 25 percentiles thresholds. mean was 403.5 ± 70.9 days. interquartile ranges 49 days short 114 long...

10.1111/rda.70058 article EN cc-by-nc-nd Reproduction in Domestic Animals 2025-04-01

This study aimed to clarify the association between percentage of follicle number by size over antral count (AFC) and subsequent reproductive performance. A total 306 Japanese Black cattle underwent timed artificial insemination (TAI) 41-62 days postpartum; AFC numbers small, medium, large follicles were recorded 10 before TAI. The cross-sectional blood flow areas dominant (DF) on day TAI corpus luteum (CL) six after recorded. ≥ 2 mm was defined as AFC, percentages each small (S-AFC%; 2-2.9...

10.1262/jrd.2024-075 article EN cc-by-nc-nd Journal of Reproduction and Development 2025-01-01

SUMMARY Acute administration of taurine produced a transient loss susceptibility to photically induced seizures in photosensitive baboons, but failed affect kindled amygdaloid convulsions rats, and cats. In addition, it was totally ineffective changing the course spontaneous status epilepticus These results suggest that taurine‐deficiency model epilepsy applies only certain types seizure‐generating conditions, apparently excluding convulsions. RÉSUMÉ L'administration élévee de diminuait...

10.1111/j.1528-1157.1975.tb06052.x article FR Epilepsia 1975-06-01
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