Kawasaki disease (KD) causes multisystemic vasculitis but infrequently manifests with deep neck infections, such as a peritonsillar abscess, or cellulitis, suppurative parapharyngeal infection, retropharyngeal abscess. As its etiology is still unknown, the diagnosis usually made based on typical symptoms. The differential between KD and infections important, considering variable head manifestations of KD. There are several reports patients who were initially diagnosed abscess computed...

Purpose There is currently little evidence to support intravenous immune globulin (IVIG) therapy for pediatric myocarditis. The purpose of our retrospective study was assess the effects IVIG in patients with presumed myocarditis on survival and recovery ventricular function determine factors associated its poor outcome. Methods We reviewed all consecutive cases left dysfunction verified by echocardiogram who had visited 3 university hospitals between January 2000 September 2009. These were...

The Usefulness of Platelet-derived Microparticle as Biomarker Antiplatelet Therapy in Kawasaki DiseaseLittle is known about platelet dynamics and the effect antiplatelet therapy disease (KD).This study sought to define activation KD patients by assaying platelet-derived microparticles (PDMPs).We measured plasma PDMPs levels 46 with using an enzyme-linked immunosorbent assay (ELISA).Blood samples were collected before, at 2-5 days, 9-15 days after intravenous immunoglobulin (IVIG) infusion, 2...

Body fat is an important source of adipokine, which associated with energy balance and inflammatory immune responses. However, the role adipokines in coronary artery complications Kawasaki disease (KD) has not yet been fully explained. We investigated whether serum adipokine level can be a useful marker for patients KD who are at higher risk developing lesion (CAL). measured levels other parameters 40 KD, 32 febrile controls, 15 afebrile controls. Interleukin (IL)-6, tumor necrosis factor...

Harlequin syndrome, which is a rare disorder caused by dysfunction of the autonomic system, manifests as asymmetric facial flushing and sweating in response to heat, exercise, or emotional factors. The syndrome may be primary (idiopathic) with benign course, can occur secondary structural abnormalities iatrogenic precise mechanism underlying idiopathic harlequin remains unclear. Here, we describe case 6-year-old boy who reported left hemifacial after exercise. He had an unremarkable birth...

Purpose Although a significant number of reports on new therapeutic options for refractory Kawasaki disease (KD) such as steroid, infliximab, or repeated intravenous immunoglobulin (IVIG) are available, their effectiveness in reducing the prevalence coronary artery lesions (CAL) remains controversial. This study aimed to define clinical characteristics patients with KD and assess effects adjuvant therapy patient outcomes. Methods We performed retrospective 38 from January 2012 March 2015....

Kawasaki disease is an acute febrile illness that usually occurs in children younger than 5 years of age. The use intravenous immunoglobulin (IVIG) within the first 10 days has been shown to reduce incidence coronary artery aneurysms significantly. relative roles repeated doses are controversial refractory (KD). Most experts recommend second retreatment with IVIG, 2 g/kg KD. However, dose-response effect third or fourth IVIG was uncertain. Although there have a significant number reports on...

Although high morning blood pressure (BP) is known to be associated with the onset of cardiovascular events in adults, data on its effects children hypertension are limited. Our retrospective study aimed define clinical characteristics (MH) and determine factors.We reviewed 31 consecutive patients hypertension, confirmed by ambulatory monitoring (ABPM). We divided these into 2 groups: MH group (n=21, 67.7%), BP above 95th percentile for age height (2 hours average after waking up) normal...

=Abstract= Kawasaki disease (KD) causes multisystemic vasculitis but rarely manifests with pulmonary symptoms. As its etiology is still unknown, there are no specific diagnostic tools available, and KD can be diagnosed only by the symptom pattern. The presence of unusual clinical manifestations often leads to delayed diagnosis. Here, we report two cases an initial presentation pneumonia. should consideration when a prolonged inflammatory reaction progressive pneumonia unresponsive...

AIMTo investigate the effects of a water extract Hwangryunhaedok-tang (HHTE) on pacemaker potentials mouse interstitial cells Cajal (ICCs).

Purpose : Clinical and laboratory findings predict a severe outcome for mucocutaneous lymph node syndrome. This study aimed to define the clinical characteristics of Kawasaki disease (KD) patients with hyponatremia determine factors associated its development. Methods Retrospective studies were performed on 114 KD who received an initial high-dose intravenous immunoglobulin (IVIG, single 2 g/kg/dose) within 10 days fever onset from January 2006 February 2008. These divided into groups. Group...

최근 전 세계적으로 메티실린내성 황색포도알균(methicillin-resistant Staphylococcus aureus [MRSA])에 의한 감염성 심내막염의 빈도가 증가하는 추세이다. 저자들은 12세 여아가 침습적 치과 치료 이후에 발생한 MRSA에 심내막염 1예를 경험하였기에 보고하는 바이다. 환아가 경부 강직을 나타내어 시행한 뇌척수액 검사상 세포 증가증 소견이 보였고 세균성 수막염을 의심하여 항생 제 치료를 시작하였으며, 입원 3병일째 혈액 배양검사에서 MRSA가 검출되었다. 심장 초음파상 승모판막의 전엽에 붙어있는 증식조직이 증명되어 항생제 치료후 호전되어 퇴원하였다. 개정된 예방을 위한 가이드라인에서는 오직 고위험군에서만 처치 전에 예방적 요법을 권장하고 있다. 본 증례는 승모판 탈출증 이외에 고위험군이 없었던 환아에서 잇몸의 출혈을 유발하는 받은 발병한 경우로서, 이후 12개월간 재발은 없었다.

Purpose: To evaluate the imaging findings of tuberculous pulmonary masses developing during antituberculous treatment pleurisy. Materials and Methods: The serial chest radiographs 134 patients with pleurisy were retrospectively assessed by two observers who recorded presence observed on follow-up their findings. Four underwent CT scans. Results: On radiographs, 29 in 14 (10.4%) comprising seven men women aged 21-52(mean, 33) years. interval between onset development varied 1 7 months....

Situs ambiguous is a very rare disease with one or less per 10,000 newborns whose organs are not in normal position. It usually has spleen and heart malformations, if it accompanied by cardiac mortality high. Intestinal malrotation also seen 70% of the newborn situs active treatment needed when intestinal found. We report case polysplenia macrosomia diabetic mother.

Ataxia-telangiectasia (AT; OMIM 208900) is a rare autosomal recessive inherited progressive neurodegenerative disorder, with onset in early childhood. AT caused by homozygous or compound heterozygous mutations ATM (OMIM 607585) on chromosome 11q22. The average prevalence of the disease estimated at 1 100,000 children worldwide. Republic Korea suggested to be extremely low, only few cases genetically confirmed thus far. Herein, we report 5-year-old Korean boy clinical features such as gait...

Abstract Background: The role of iron in children with Kawasaki disease (KD) and the importance deficiency anemia (IDA) KD are not fully known. We aimed to evaluate effects IDA on clinical outcomes patients inflammation-induced hepcidin leptin development KD. Methods: A total 50 47 age-matched controls were enrolled. Hepcidin, leptin, tumor necrosis factor-α (TNF-α) interleukin-6 (IL-6) levels measured by an enzyme-linked immunosorbent assay work-up was performed before after IVIG therapy,...