A5083168631- Musculoskeletal pain and rehabilitation
- Intracerebral and Subarachnoid Hemorrhage Research
- Shoulder Injury and Treatment
- Cancer-related gene regulation
- Spine and Intervertebral Disc Pathology
- Healthcare and Venom Research
- Endometriosis Research and Treatment
- Cerebral Palsy and Movement Disorders
- Myofascial pain diagnosis and treatment
- S100 Proteins and Annexins
- Tendon Structure and Treatment
- Nerve Injury and Rehabilitation
- Peripheral Nerve Disorders
- Neurofibromatosis and Schwannoma Cases
- Ecology and biodiversity studies
- Renin-Angiotensin System Studies
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Urticaria and Related Conditions
- Cytokine Signaling Pathways and Interactions
- Protease and Inhibitor Mechanisms
- Nutrition and Health in Aging
- Dysphagia Assessment and Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Frailty in Older Adults
Kyung Hee University
2009-2023
Kyung Hee University Medical Center
2009-2022
Kyung Hee University Hospital at Gangdong
2019
Kyung Hee University Dental Hospital
2017-2018
Eulji University
2005
Objective To investigate balance control according to the severity of knee osteoarthritis (OA) using clinical tests and Tetra-ataxiometric posturography (Tetrax®). Method A total 80 patients with primary OA classified American College Rheumatology criteria, 40 age-matched controls were enrolled in this study. Of those OA, 39 had mild (Kellgren-Lawrence [KL] grade 1, 2) other 41 moderate severe (KL 3, 4). The postural capabilities subjects assessed timed up go test (TUG), Berg scale (BBS),...
Rotenone, a mitochondrial complex I inhibitor, can induce the pathological features of Parkinson's disease (PD). In present study, naringin, grapefruit flavonoid, inhibited rotenone-induced cell death in human neuroblastoma SH-SY5Y cells. We assessed and apoptosis by measuring mitogen-activated protein kinase (MAPKs) caspase (CASPs) activities performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, 4,6-diamidino-2-phenylindole (DAPI) staining, terminal...
To evaluate the relationships between tongue pressure and different aspects of oral-phase swallowing function.We included 96 stroke patients with dysphagia, ranging in age from 40 to 88 years (mean, 63.7 years). Measurements were obtained Iowa Oral Performance Instrument, a device established normative data. Three trials maximum performance performed for lip closure (LP), anterior hard palate-to-tongue (AP), posterior (PP); buccal-to-tongue pressures on both sides also recorded...
To investigate the efficacy of ultrasonography (US)-guided injections in patients with low lumbar facet syndrome, compared that who received fluoroscopy (FS)-guided injections.Fifty-seven subjects syndrome spine L4-5 and L5-S1 levels were randomly divided into two groups to receive intraarticular joint. One group FS-guided joint other US-guided injections. Treatment effectiveness was assessed using a visual analogue scale (VAS), physician's patient's global assessment (PhyGA, PaGA), modified...
Monomelic amyotrophy (MMA), also known as Hirayama disease, is a sporadic juvenile muscular atrophy in the distal upper extremities. This disorder rarely involves proximal extremities and presents minimal sensory symptoms with no motor neuron (UMN) signs. It caused by anterior displacement of posterior dural sac compression cervical cord during neck flexion. An 18-year-old boy visited our clinic 5-year history left extremity pain slowly progressive weakness affecting shoulder. Atrophy was...
To investigate the differences in biomechanical parameters measured by gait analysis systems between healthy subjects and with plantar fasciitis (PF), to compare 'normal, barefooted' arch building participants.The researchers evaluated 15 (30 feet) bilateral foot pain (15 unilateral who had a clinical diagnosis of PF. Additionally, 17 (34 no heel were recruited. Subjects excluded if they traumatic event, prior surgery or fractures lower limbs, leg length discrepancy 1 cm greater, body mass...
Objective To compare the efficacy of ultrasonography guided stellate ganglion block (US-SGB) with that blind SGB in management stroke patients complex regional pain syndrome (CRPS) type 1. Method Forty-two post-stroke CRPS were randomly assigned to either US-guided (22 patients) or group (20 patients). The mean age and groups was 61.3±5.6 years 59.1±4.5 years. We performed two blockades at 7-day intervals on affected side CRPS. Pain intensity, using a visual analog score (VAS), clinical...
To assess the cross-sectional area (CSA) of muscles for investigating occurrence asymmetry paraspinal (multifidus and erector spinae) psoas its relation to chronicity unilateral lumbar radiculopathy using magnetic resonance imaging (MRI).This retrospective study was conducted between January 2012 December 2014. Sixty one patients with L5 were enrolled: 30 had a symptom duration less than 3 months (group A) 31 or more B). Axial MRI measured CSA at middle lower margin upper vertebra vertebra,...
Vitamin B12 (B12) is involved as a cofactor in the synthesis of myelin. A lack impairs peripheral nerve production, which can contribute to sarcopenia. In this cross-sectional study, we aimed investigate relationship between insufficiency and sarcopenia community-dwelling older Korean adults. total 2325 (1112 men; 1213 women) adults aged 70-84 years were recruited. The tools used for based on Asian Working Group Sarcopenia (AWGS) guidelines. Individuals with low appendicular skeletal muscle...
Transforming growth factor, beta receptor II (TGFBR2) is mainly expressed by neurons in the central nervous system, and reduced neuronal TGFBR2 signaling results accelerated age-dependent neurodegeneration. To investigate whether polymorphisms are associated with ischemic stroke (IS) intracerebral hemorrhage (ICH), two single nucleotide (SNPs) of gene (rs764522, –1444C/G; rs2228048, Asn389Asn) were selected genotyped direct sequencing 247 patients (120 IS 127 ICH) 655 control subjects (260...
Stroke is a heterogeneous disease caused by different pathogenic mechanisms. Several candidate genes for stroke have been proposed, but few replicated. Matrix metalloproteinases (MMPs) are expressed following stroke. We investigated the association of single nucleotide polymorphisms (SNPs) MMP3 gene with in Korean population. This study included 186 patients [116 ischemic (IS) and 70 intracerebral hemorrhage (ICH)] 668 age-matched control subjects (267 IS 401 ICH). Three SNPs [rs520540...
Neuronal expression of ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) has been demonstrated after brain ischemia.To investigate whether ABCB1 polymorphisms are associated with the development, risk factors (hypertension, dyslipidemia, and diabetes mellitus), severity (National Institutes Health Stroke Scale, NIHSS), sequelae (Modified Barthel Index, MBI) ischemic stroke (IS), four single nucleotide (SNPs) gene [rs4148727, promoter, -154T>C; rs3213619, 5'-untranslation region...
Schwannomas are benign, usually slow-growing tumors that originate from Schwann cells surrounding peripheral, cranial, or autonomic nerves. The most common form of these is acoustic neuroma. the brachial plexus quite rare, and symptomatic schwannomas even rarer. A 47-year-old woman presented with a 1-year history dysesthesia, neuropathic pain, mild weakness right upper limb. Results physical examination electrodiagnostic studies supported diagnosis as thoracic outlet syndrome. Conservative...
To evaluate the association between balance function and asymmetry of knee extension strength in an elderly Korean population.The extensors each leg was measured 306 community-dwelling subjects (age, 76.70±4.85 years) 25 young healthy 34.23±8.93 years). Based on difference both legs, were divided into symmetric (n=128) asymmetric (n=178) groups using cutoff 20%. We determined postural control ability InBody posturography, Berg Balance Scale (BBS), Timed Up Go test (TUG) Short Physical...
Objective To determine whether ACE insertion/deletion (I/D) polymorphism is associated with the ossification of posterior longitudinal ligament (OPLL) spine in Korean population. Methods A case-control study was conducted to investigate association between I/D angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 (ACE) gene and OPLL. The 95 OPLL patients 274 control subjects were recruited. Polymerase chain reaction for genotyping performed. difference compared using contingency χ2 test...
BACKGROUND:Dysphagia and dysarthria tend to coexist in stroke patients. Dysphagia can reduce patients' quality of life, cause aspiration pneumonia increased mortality. OBJECTIVE:To evaluate correlations among swallowing function parameters acoustic vowel space values patients with . METHODS:Data from dysphagia were collected. The formant parameter representing the resonance frequency vocal tract as a two-dimensional coordinate point was measured for /a/, /ae/, /i/, /u/vowels, quadrilateral...