- Ginseng Biological Effects and Applications
- Tryptophan and brain disorders
- Genetics and Neurodevelopmental Disorders
- Natural product bioactivities and synthesis
- Heavy Metal Exposure and Toxicity
- Pharmacological Effects of Natural Compounds
- Insect Pest Control Strategies
- Neuroinflammation and Neurodegeneration Mechanisms
- Biometric Identification and Security
- Genomics, phytochemicals, and oxidative stress
- Environmental Toxicology and Ecotoxicology
- Antioxidant Activity and Oxidative Stress
- Immune Cell Function and Interaction
- User Authentication and Security Systems
- Medicinal Plant Extracts Effects
- Reproductive System and Pregnancy
- Trace Elements in Health
- Diabetes and associated disorders
- Video Surveillance and Tracking Methods
- Industrial Vision Systems and Defect Detection
- Phosphodiesterase function and regulation
- Advanced Steganography and Watermarking Techniques
- Phytochemistry and Biological Activities
- Epigenetics and DNA Methylation
- Pesticide Exposure and Toxicity
Soonchunhyang University
2013-2024
King Saud University
2021
Seoul National University
2017
Kyung Hee University Medical Center
2006-2014
University of Florida
2010
Kyung Hee University
2007-2010
Keimyung University
2010
Kunsan National University
2009
Kangwon National University
2009
Electronics and Telecommunications Research Institute
2009
The current health concern to the entire world is chronic respiratory disease caused by coronavirus 2 (COVID-19). A specific treatment or proper therapy still lacking, and investigations from across for drug/vaccine development towards control are in progress. Coronavirus replication takes place conversion of polypeptide into functional protein this occurs due key enzyme Main protease (Mpro). Therefore, identification natural effective Mpro inhibitors could be a safe promising approach...
In recent years, studies have focused on the therapeutic properties of probiotics to eliminate pathogenic microorganisms associated with various diseases. Lactobacilli are important groups that been found possess many health-promoting activities. This study was carried out isolate LactobacillusreuteriLR12 and L. lactisLL10 from pineapple puree. The invitro analysis evaluate probiotic characteristics isolated bacteria included survival in bile acid tolerance. cell-free supernatant reuteri...
Rotenone, a mitochondrial complex I inhibitor, can induce the pathological features of Parkinson's disease (PD). In present study, naringin, grapefruit flavonoid, inhibited rotenone-induced cell death in human neuroblastoma SH-SY5Y cells. We assessed and apoptosis by measuring mitogen-activated protein kinase (MAPKs) caspase (CASPs) activities performing 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, 4,6-diamidino-2-phenylindole (DAPI) staining, terminal...
In this study, phyto-constituents, anti-bacterial and anticancer activity of
In a surveillance camera environment, the detection of standing-pigs in real-time is an important issue towards final goal 24-h tracking individual pigs. this study, we focus on depth-based with "moving noises", which appear every night commercial pig farm, but have not been reported yet. We first apply spatiotemporal interpolation technique to remove moving noises occurring depth images. Then, detect by utilizing undefined values around them. Our experimental results show that method...
Extensive application of pesticide in agricultural field affects the enzymatic activity non-target animals, including fishes. In this study, impact sublethal concentration fenvalerate on marker enzymes freshwater Zebra fish was evaluated. Pesticide-induced stress can specifically affect non target fishes, through elevated level reactive oxygen species which is responsible for biochemical, cell metabolism and physiological activities. The oxidative mediated by at sub lethal concentrations...
A germacrane-type sesquiterpenoid was isolated and purified from a methanol extract of the roots Valeriana fauriei (RVF) through open column chromatography using silica gel. This compound verified to be heishuixiecaoline by spectroscopic analysis. for first time RVF. Quantitative analysis RVF cultivated three different regions (Eumseong, Jinbu, Jinan regions) performed combining high-performance liquid with photodiode array detector. The in Jinbu region showed highest content (9.23 mg/g). In...
Depression is one of the most commonly diagnosed neuropsychiatric diseases, but underlying mechanism and medicine are not well-known. Although Panax ginseng has been reported to exert protective effects in various neurological studies, little information available regarding its antidepressant effects. Here, we examined effect P. extract (PGE) a chronic restraint stress (CRS)-induced depression model mice. Oral administration PGE for 14 d decreased immobility (depression-like behaviors) time...
This context was investigated to assess the in vitro antioxidant, anti-diabetic, anti-obesity, and angiotensin-converting enzyme (ACE) inhibition traits of Punica granatum fruits peel extract. Initially, among various extracts tested, aqueous ethanolic depicted presence diverse phytoconstituents. In antioxidative properties were determined using standard methodologies. Results showed that had IC50 values 471.7 509.16 μg/mL, respectively terms 1,1,diphenyl 2,2,picrylhydrazyl scavenging....
Inflammation and pain triggers several pathological illnesses. Synthetic drugs used for the controlling of inflammatory conditions convey significant toxic effects. Global scientific community continually attempt to improve effective, economic harmless naturally derived remedies against inflammation pain. The present study aimed quantify phytochemical constituents freshly cultivated Spirulina targeted examining anti-inflammatory analgesic activity extract (SE) from Arthrospira platensis.The...
The Panax ginseng plant is used as an herbal medicine. Phytosterols of P. have inhibitory effects on inflammation-related factors in HepG2 cells. (e.g., stigmasterol and β-sitosterol) the roots grown under various conditions were analyzed using high-performance liquid chromatography. this study collected from three cultivation areas Korea (i.e., Geumsan, Yeongju, Jinan) differed by year 4 years, 5 6 years) production process straight ginseng, red white ginseng). concentrations β-sitosterol...
We investigated the association of polymorphisms in two renin-angiotensin system-related genes, expressed as angiotensinogen (AGT) and angiotensin II type 1 receptor (AGTR1), with blood lead levels lead-related pressure lead-exposed male workers Korea. A cross-sectional study involving 808 Korea was conducted using a restriction fragment length polymorphism-based strategy to differentiate various genotypes AGT AGTR1 genes. The clinical characteristics modifiers estimated after adjustment for...
The main objective of the present study is to determine lead toxicity on various sizes zebra fish in soft and hard water. Lead analysis was carried out laboratory trials for four days at concentrations determination LC50 value. Zebra grouped into (G1-G4) treated with 96 h. induced behavioural changes fish. In case G1 (1.5 ± 0.2 cm length) values ranged from 27.2 1.8 mg/L 9.7 1.3 mg/L. G2 (2.0 fish, value 37.01 2.3 it reduced as 32.03 3.4 after 48 G3 group (2.5 length fish), 38.78 2.4 24 h...
In this study, 104 bacteria were isolated from the gut of Penaeus indicus. The morphologically different bacterial isolates screened for probiotic properties. strain D5 showed potent activity against various bacteria. Bacillus subtilis 17 mm zone inhibition sp., 19 Pseudomonas 22 Vibrio and Micrococcus sp. growth bacterocin production in relation with incubation time was evaluated. Bacteriocin found to be high at stationary phase reduced considerably after fifth day. Bacterial maximum pH 7.0...
This paper presents a new method, based on multiple-model adaptive estimation approach, to determine the most probable shape of spacecraft in orbit among number candidate models while simultaneously recovering observed resident space object’s inertial orientation and trajectory. Multiple-model uses parallel bank filters provide multiple object state estimates, where each filter is purposefully dependent mutually unique model. Estimates conditional probability model given available...
The preventive and therapeutic mechanisms in multiple sclerosis are not clearly understood. We investigated whether Hyungbangpaedok-san (HBPDS), a traditional herbal medicine, has beneficial effect experimental autoimmune encephalomyelitis (EAE) mice immunized with myelin oligodendrocyte glycoprotein peptide (MOG35-55). Onset-treatment 4 types of HBPDS (extracted using distilled water 30%/70%/100% ethanol as the solvent) alleviated neurological signs, extracted within 30% (henceforth called...
Investigation for a naturally occurring anti-obesity drug has become the need of society all over world. Betulinic acid (BA) is lupane-type pentacyclic triterpene and sourced from various organisms. This high potential biologically active molecule reported to have effect. In this study, we report molecular mechanism action BA that underlies activity also an improved method its isolation common teak tree.Mouse pre-adipocyte cells were used develop hyperlipidemic conditions in vitro. Change...
Fenvalerate is widely used insecticide that severely causes toxicological effects in various aquatic organisms especially fish. Physiochemical factors of water influenced fenvalerate toxicity. This study investigated physiochemical content water, the on mortality, changes protein profile gut Zebra fish and digestive enzymatic after 28 days exposure. was exposed to ranges LC50 value determined. Alkaline pH high temperature critically mortality. The sub lethal concentration decreased total...