A5072335707- Luminescence Properties of Advanced Materials
- Luminescence and Fluorescent Materials
- Nanoplatforms for cancer theranostics
- Perovskite Materials and Applications
- Radiation Detection and Scintillator Technologies
- Advanced biosensing and bioanalysis techniques
- Quantum Dots Synthesis And Properties
- Gold and Silver Nanoparticles Synthesis and Applications
- Photodynamic Therapy Research Studies
- Biosensors and Analytical Detection
- Inorganic Fluorides and Related Compounds
- Solid State Laser Technologies
- Chalcogenide Semiconductor Thin Films
- bioluminescence and chemiluminescence research
- Advanced Biosensing Techniques and Applications
- Nanoparticle-Based Drug Delivery
- Copper-based nanomaterials and applications
- Nanocluster Synthesis and Applications
- Advanced Photocatalysis Techniques
- Optical Imaging and Spectroscopy Techniques
- Electronic and Structural Properties of Oxides
- Conducting polymers and applications
- Analytical Chemistry and Sensors
- CO2 Sequestration and Geologic Interactions
- Photoacoustic and Ultrasonic Imaging
Changchun Institute of Optics, Fine Mechanics and Physics
2015-2025
Chinese Academy of Sciences
2015-2025
Changchun University of Science and Technology
2024-2025
University of Amsterdam
2008-2018
State Key Laboratory of Biotherapy
2012-2018
Sichuan University
2012-2018
University of Chinese Academy of Sciences
2010-2015
Academia Sinica
2014
A highly efficient multifunctional nanoplatform for simultaneous upconversion luminescence (UCL) imaging and photodynamic therapy has been developed on the basis of selective energy transfer from multicolor luminescent NaYF(4):Yb(3+),Er(3+) nanoparticles (UCNPs) to photosensitizers (PS). Different popular approaches based electrostatic or hydrophobic interactions, over 100 photosensitizing molecules were covalently bonded every 20 nm UCNP, which significantly strengthened UCNP-PS linkage...
The application of upconversion nanoparticles (UCNPs), especially in vivo, has so far been hampered by their relatively low efficiency. In this work, a strategy Li+ doping was revisited with the aim enhancing UV to blue UC luminescence NaYF4:Yb3+, Tm3+ nanocrystals. We have demonstrated that short wavelength emission bands were indeed significantly enhanced. Compared lithium-free Tm3+, intensities 452 nm and 479 NPs co-doped 7 mol% ions increased 8 5 times, respectively. mechanism...
Strong red upconversion luminescence of rare-earth ions doped in nanocrystals is desirable for the biological/biomedical applications. In this paper, we describe great enhancement emission (4F9/2 → 4I15/2 transition Er3+ ion) NaYF4:Yb3+, at low doping level, which ascribed to effectiveness multiphonon relaxation process due existence citrate as a chelator and cross between ions. The dissolution−recrystallization transformation, governing both intrinsic crystalline phase (cubic and/or...
Coating a homogeneous layer outside the core nanoparticles has become common method to improve optical properties of nanoparticles. For rare earth ion-doped nanoparticles, although coating is found enhance upconversion luminescence, large deviation in reported enhancement amplitude, however, demonstrates lack complete picture mechanism. In this work, we have performed steady-state and time-resolved spectroscopic studies on one most efficient nanosystems − β-NaYF4:Yb3+,Er3+...
The novel nanostructures have been designed to balance the robustness of upconversion emission and FRET efficiency for image-guided photodynamic therapy under triggering 808 nm light.
3-Mercaptopropionic acid stabilized CdTe/CdS core/shell quantum dots (QDs) were prepared in an aqueous solution following the synthetic route of successive ion layer adsorption and reaction. The photoluminescence yield CdTe QDs could reach 40%, from 8% bare core, via control shell thickness. exhibited also a significant red shift emission excitation peaks when grew. experiments revealed that evolved type I to II structures with increase thickness, evolution process is affected by core size,...
It is generally accepted that a lanthanide ions based upconversion material follows an activator low doping strategy (normally <3 mol%), because of the restriction harmful concentration quenching effect. Here, we demonstrate this limitation can be broken in nanostructures. Simply by using inert shell coating strategy, effect for (Er3+) could eliminated and highly efficient luminescence realized fully doped nanostructure, e.g. NaErF4@NaYF4. More importantly, novel nanostructure achieves some...
Photoswitchable materials are important in broad applications. Recently appeared inorganic photoswitchable upconversion nanoparticles (PUCNPs) become a competitive candidate to surmount the widespread issue of organic counterparts —photobleaching. However, current PUCNPs follow solely Yb3+/Nd3+ cosensitizing mode, which results complex multilayer doping patterns and imperfectness switching UV–blue region. In this work, we have adopted new strategy construct Nd3+ free...
Upconversion emission dynamics have long been believed to be determined by the activator and its interaction with neighboring sensitizers. Herein this assumption is, however, shown invalid for nanostructures. We demonstrate that excitation energy migration greatly affects upconversion dynamics. "Dopant ions' spatial separation" nanostructures are designed as model systems intimate link between random nature of time behavior is unraveled theoretical modelling confirmed spectroscopically....
Abstract Internal hydroxyl impurity is known as one of the main detrimental factors affecting upconversion (UC) efficiency luminescence (UCL) nanomaterials. Different from surface/ligand-related emission quenching which can be effectively diminished by, e.g., core/shell structure, internal easy to introduced in synthesis but difficult quantified and controlled. Therefore, it becomes an obstacle fully understand relevant UC mechanism improve Here we report a progress quantifying large-range...
The upconversion luminescence (UCL) in the second near-infrared window (NIR-II) is highly attractive due to its excellent performance high-resolution bioimaging, anticounterfeiting, and temperature sensing. However, upconvertion nanoparticles (UCNPs) are normally emitted visible light, potentially impacting imaging quality. Here, a monochromatic Er
The incorporation of two-dimensional (2D) perovskite onto the three-dimensional (3D) structure presents an effective approach for passivating surface defects, optimizing energy level alignment, and stabilizing active layers in solar cells (PSCs), thereby facilitating realization highly efficient stable devices. However, it remains a formidable challenge to achieve precise composition controllable 2D/3D heterojunctions through solution processes. Additionally, uncontrolled cation exchange...
The concentration quenching threshold of upconversion luminescence was broken through for the first time via a designed strategy: spatial separation emitter doping area.
High quality triangular silver nanoprisms were obtained through simple one-step plasmon-mediated method.
The newly developed NaErF<sub>4</sub> system offers a new strategy to design excellent theranostic nanoplatform for multimodality imaging-guided therapy.
Photodynamic therapy (PDT) has been widely used in tumor due to its high spatial-temporal control and noninvasiveness. However, clinical application is limited by weak efficacy, shallow tissue penetration, phototoxicity. Herein, a facile theranostic nanoplatform based on photoswitchable lanthanide-doped nanoparticles was designed. Typically, these had UV-blue 1525 nm emission upon 980 excitation 800 excitation. We further for achieving real-time near-infrared (NIR)-IIb imaging (800 nm) with...
Multi-sized quantum dots (QDs) donors and tailor-made gold nanorods (GNRs) are employed to form a FRET nanoplatform for homogeneous immunoassays developed analysis of multiple virus antigens. The single GNRs/multiple QDs nanocomposite based nanosensor offers simple sensitive approach analytes detection in format.
Abstract Accurate quantitation of intracellular pH (pH i ) is great importance in revealing the cellular activities and early warning diseases. A series fluorescence-based nano-bioprobes composed different nanoparticles or/and dye pairs have already been developed for sensing. Till now, biological auto-fluorescence background upon UV-Vis excitation severe photo-bleaching dyes are two main factors impeding accurate quantitative detection . Herein, we a self-ratiometric luminescence nanoprobe...
Dye sensitization is becoming a new dimension to highly improve the upconversion luminescence (UCL) of lanthanide-doped nanoparticles (UCNPs). However, there still lack general understanding dye-UCNPs interactions, especially confused large mismatch between inputs and outputs. By taking dye-sensitized NaYF4:Yb/Er@NaYF4:Nd UCNPs as model system, we not only revealed in-depth energy-dissipative process for UCL but also confirmed first ever experimental observation energy back transfer (EBT) in...
A new strategy for efficient <italic>in vivo</italic> image-guided photodynamic therapy (PDT) has been demonstrated utilizing a ligand-exchange constructed upconversion-C<sub>60</sub> nanophotosensitizer.
LRET-based optical biosensor of an aptamer-upconversion conjugate was constructed. It is demonstrated that photosensitized breakage and damage aptamers are eliminated by employing UCNPs as donors, the as-designed specific sensitive in detection ATP.