- Luminescence Properties of Advanced Materials
- Advanced biosensing and bioanalysis techniques
- Luminescence and Fluorescent Materials
- Nanoplatforms for cancer theranostics
- Gas Sensing Nanomaterials and Sensors
- Inorganic Fluorides and Related Compounds
- Advanced Nanomaterials in Catalysis
- Biosensors and Analytical Detection
- Analytical Chemistry and Sensors
- Electrochemical sensors and biosensors
- Nanocluster Synthesis and Applications
- Lipid metabolism and biosynthesis
- Photosynthetic Processes and Mechanisms
- Advanced Chemical Sensor Technologies
- Inorganic Chemistry and Materials
- ZnO doping and properties
- Carbon and Quantum Dots Applications
- Perovskite Materials and Applications
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Molecular Sensors and Ion Detection
- Metal-Organic Frameworks: Synthesis and Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Copper-based nanomaterials and applications
- Crystal Structures and Properties
State Key Laboratory on Integrated Optoelectronics
2019-2025
Jilin University
2005-2025
Qingdao University
2018-2025
Affiliated Hospital of Qingdao University
2024
Jiamusi University
2024
Zhejiang University of Technology
2022
Changchun Institute of Optics, Fine Mechanics and Physics
2010-2021
Academia Sinica
2021
Biomechanics Institute of Valencia
2021
Jilin Province Science and Technology Department
2020
A highly efficient multifunctional nanoplatform for simultaneous upconversion luminescence (UCL) imaging and photodynamic therapy has been developed on the basis of selective energy transfer from multicolor luminescent NaYF(4):Yb(3+),Er(3+) nanoparticles (UCNPs) to photosensitizers (PS). Different popular approaches based electrostatic or hydrophobic interactions, over 100 photosensitizing molecules were covalently bonded every 20 nm UCNP, which significantly strengthened UCNP-PS linkage...
Synthesis of red emissive carbon dots (CDs) is highly desirable for sensing applications, as they still remain bottlenecks in terms precursor synthesis and product purification. Herein, we have designed a new strategy realizing efficient CD optimal emission at 610 nm (fluorescence quantum yield ca. 24.0%) based on solvothermal treatment citric acid thiourea using dimethylformamide solvent. Further investigations reveal that the conjugating sp2-domain controlling incorporation nitrogen...
The novel nanostructures have been designed to balance the robustness of upconversion emission and FRET efficiency for image-guided photodynamic therapy under triggering 808 nm light.
Photoswitchable materials are important in broad applications. Recently appeared inorganic photoswitchable upconversion nanoparticles (PUCNPs) become a competitive candidate to surmount the widespread issue of organic counterparts —photobleaching. However, current PUCNPs follow solely Yb3+/Nd3+ cosensitizing mode, which results complex multilayer doping patterns and imperfectness switching UV–blue region. In this work, we have adopted new strategy construct Nd3+ free...
Monodisperse water-soluble hexagonal phase Ln(3+)-doped NaGdF(4) upconverting nanocrystals (UCNCs) have been successfully fabricated by means of a fast, facile, and environmentally friendly microwave-assisted route with polyethylenimine as the surfactant. Fine-tuning UC emission from visible to near-IR finally white light has achieved. Furthermore, studies magnetic resonance imaging well magnetization (magnetization-magnetic field curves) targeted recognition properties FA-coupled...
Lipid droplets (LDs), which are ubiquitous organelles existing in almost all eukaryotic cells, have attracted a lot of attention the field cell biology over last decade. For biological study LDs via fluorescence imaging, superior LD fluorescent probes with environmental polarity-sensitive character highly desired and powerful but very scarce. Herein, we newly developed such kind probe named LDs-Red enables us to visualize further reveal their polarity information. This displays advantages...
Abstract Investigations on the utilization efficiency and bioactivity of enzyme nanocarriers are critical for realizing sensitive biosensors. Herein, hierarchically porous enzyme@peptide‐directed metal–organic frameworks (enzyme@MOFs‐P) nanoarchitectures constructed by implemented site‐selective epitaxial growth to create mesopore defect structures. The expanded size pores provides suitable space homogeneously accommodating enzymes enhances interfacial contact with enzymes, as well reducing...
Water-soluble pure hexagonal-phase NaYF4:Yb3+,Er3+/Tm3+ nanoparticles were obtained by an ionothermal method for the first time which offers a new alternative in synthesizing such materials.
Monodisperse water-soluble LaF3:Ln3+ nanocrystals (NCs) have been successfully fabricated via a fast, facile and environmentally-friendly microwave-assisted modified polyol process with polyvinylpyrrolidone (PVP) as an amphiphilic surfactant. The obtained NCs can be well dispersed in hydrophilic solutions small sizes the range of 9–12 nm. (Ln = Eu, Nd, Ce, Tb, Yb, Er, Ho Tm) unique feature up–down conversion from visible to NIR emission owing ladder-like arranged energy levels Ln3+...
The newly developed NaErF<sub>4</sub> system offers a new strategy to design excellent theranostic nanoplatform for multimodality imaging-guided therapy.
Abstract Lipid droplets (LDs) are important organelles associated with many physiological processes as well diseases. To visualize LDs and study their versatile functions, the fluorescence imaging technique is one of most powerful tools. Thus, development fluorescent probes for has attracted increased attention in recent years. Herein, a new probe Ph‐Red developed its application carefully demonstrated. The compact single‐benzene‐based molecular structure can be easily synthesized via...
An efficient NIR-IIb nanoprobe was designed with the 1525 nm QY of 13.92% for cerebrovascular microscopy imaging and various physiological dynamic imaging.
A cost-effective and highly reproducible capillary-based surface-enhanced Raman scattering (SERS) platform for sensitive, portable detection identification of fentanyl is presented. Through encapsulating gold trisoctahedra (Au TOH) in the capillary tube first time, SERS was constructed by combining superior properties Au TOH advantages capillaries signal amplification, facile sample extraction, trace analysis. The effects size density on performance were investigated experiments simulations,...
Background: Lipid droplets (LDs) are critical organelles associated with many physiological processes in eukaryotic cells.To visualize and study LDs, fluorescence imaging techniques including the confocal as well emerging super-resolution of stimulated emission depletion (STED), have been regarded most useful methods.However, directly limited by availability advanced LDs fluorescent probes, performances increasingly unsatisfied respect to fast research progress LDs.Methods: We herein newly...
Two low-dimensional hybrid copper halides, (2,2'-bipy)Cu(3)I(3) (1) and (2,2'-bipy)Cu(4)I(4) (2) (2,2'-bipy = 2,2'-bipyridine), with novel D6R (double six-membered rings) Cu(6)I(6) cores were synthesized by hydro(solvo)thermal reactions characterized single-crystal X-ray diffraction.
Multi-sized quantum dots (QDs) donors and tailor-made gold nanorods (GNRs) are employed to form a FRET nanoplatform for homogeneous immunoassays developed analysis of multiple virus antigens. The single GNRs/multiple QDs nanocomposite based nanosensor offers simple sensitive approach analytes detection in format.