A5085536490- Ultrasound Imaging and Elastography
- Advanced MRI Techniques and Applications
- Elasticity and Material Modeling
- Liver Disease Diagnosis and Treatment
- Ultrasonics and Acoustic Wave Propagation
- Meningioma and schwannoma management
- Osteoarthritis Treatment and Mechanisms
- Automotive and Human Injury Biomechanics
- Photoacoustic and Ultrasonic Imaging
- Advanced Neuroimaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Sports injuries and prevention
- MRI in cancer diagnosis
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
- Traumatic Brain Injury Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Effects of Vibration on Health
- Medical Imaging Techniques and Applications
- Pituitary Gland Disorders and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Cardiac Valve Diseases and Treatments
- Liver Disease and Transplantation
- Medical Imaging and Analysis
- Myofascial pain diagnosis and treatment
Mayo Clinic
2015-2025
Mayo Clinic in Arizona
2018-2024
Mayo Clinic in Florida
2024
WinnMed
2023
University Radiology
2021
University of Illinois Chicago
2013-2016
Knowledge of mechanical properties tissue-engineered cartilage is essential for the optimization tissue engineering strategies. Microscopic magnetic resonance elastography (μMRE) a recently developed MR-based technique that can nondestructively visualize shear wave motion. From observed pattern in MR phase images (e.g., modulus or stiffness) be extracted. For quantification dynamic small and stiff cartilage, μMRE needs to performed at frequencies kilohertz range. However, greater than 1 kHz...
Circulating extracellular vesicles (EVs) are a novel and emerging biomarker for nonalcoholic steatohepatitis (NASH). It has been demonstrated that total circulating EVs hepatocyte‐derived elevated in male mice with diet‐induced NASH. How change over time other cellular sources of NASH have not determined. Our objective was to define the quantitative evolution hepatocyte‐derived, macrophage‐derived, neutrophil‐derived, platelet‐derived female dietary Fluorescently labeled antibodies nanoscale...
To test the clinical feasibility and usefulness of slip interface imaging (SII) to identify quantify degree tumor-brain adhesion in patients with vestibular schwannomas.S With institutional review board approval after obtaining written informed consent, SII examinations were performed nine schwannomas. During acquisition, a low-amplitude mechanical vibration is applied head pillow-like device placed coil resulting shear waves are imaged by using phase-contrast pulse sequence motion-encoding...
To investigate the ability of slip interface imaging (SII), a recently developed magnetic resonance elastography (MRE)-based technique, to predict degree meningioma-brain adhesion, using findings at surgery as reference standard.With Institutional Review Board approval and written informed consent, 25 patients with meningiomas >2.5 cm in maximal diameter underwent preoperative SII assessment. Intracranial shear motions were introduced soft, pillow-like head driver resulting displacement...
Abstract Purpose To evaluate the test–retest repeatability of a rapid, free‐breathing two‐dimensional (2D) MR elastography (MRE) technique and to assess reliability liver‐stiffness measurements compared with conventional breath‐hold MREs. Methods Fifteen 115 participants were enrolled in technical measurement equivalence assessment cohorts, respectively. All underwent rapid 2D MRE (twice cohort) on 1.5T scanners. Both methods have four phase offsets over one harmonic motion cycle at 60 Hz;...
Purpose To present a new technique for concurrent MR elastography (MRE) and diffusion MRI: diffusion-MRE (dMRE). Methods In dMRE, shear wave motion signal decay due to are encoded into the phase magnitude components of by using pair bipolar gradients both motion-sensitization encoding. The pulse sequence timing is adjusted so that sensitive coherent incoherent intravoxel motions. shape, number, duration gradient lobes can be provide flexibility encoding efficiency. this proof-of-concept...
To introduce a newly developed technique (DTI-MRE) for the simultaneous acquisition of diffusion tensor imaging (DTI) and 3D-vector field magnetic resonance elastography (MRE) data, to demonstrate its feasibility when applied in vivo mouse brain.In DTI-MRE, encoding is achieved by using series diffusion/motion-sensitizing gradients (dMSGs) with specific timing directions. By adjusting duration dMSGs time mechanical vibration frequency, shear wave motion are encoded into MR phase magnitude...
Purpose To introduce newly developed MR elastography (MRE)‐based dual‐saturation imaging and dual‐sensitivity motion encoding schemes to directly measure in vivo skull–brain motion, study the coupling volunteers with these approaches. Methods Six were scanned a high‐performance compact 3T‐MRI scanner. The MRE images obtained where skull brain acquired fat‐ water‐suppression scans, respectively. A scheme was applied estimate heavily wrapped phase by simultaneous acquisition of both low‐...
To determine whether tumor shear stiffness, as measured by magnetic resonance elastography, corresponds with intratumoral consistency and histotype. A total of 88 patients 89 meningiomas (grade 1, 74 typical [13 fibroblastic, 61 non-fibroblastic]; grade 2, 12 atypical; 3, 3 anaplastic) were prospectively studied, each undergoing preoperative MRE in conjunction T1-, T2- diffusion-weighted imaging. Contrast-enhanced T1-weighted sequences also obtained. Tumor was evaluated heterogeneous or...
Increasing concerns have been raised about the long-term negative effects of subconcussive repeated head impact (RHI). To elucidate RHI injury mechanisms, many efforts studied how impacts affect skull-brain biomechanics and found that mechanical interactions at interface dampen isolate brain motions by decoupling from skull. Despite intense interest, in vivo quantification functional state remains difficult. This study developed a magnetic resonance elastography (MRE) based technique to...
This paper reports diffusion weighted MRI measurements of cyclohexane in a novel tensor phantom composed hollow coaxial electrospun fibers (average diameter 10.2 μm). Recent studies the demonstrated its potential as calibration standard at low b values (less than 1000 s/mm<;sup>2<;/sup>) for mean diffusivity and fractional anisotropy. In this paper, we extend characterization heterogeneous, anisotropic material to high (up 5000 s/mm<;sup>2<;/sup>), where apparent diffusive motion exhibits...
Pituitary adenoma is one of the most common primary intracranial neoplasms. Most these tumors are soft, but up to 17% may have a firmer consistency. Therefore, knowing tumor consistency in preoperative setting could be helpful. Multiple imaging methods been proposed predict consistency, results controversial. This study aimed evaluate efficacy MR elastography (MRE) predicting and its potential use series patients with pituitary adenomas.
Meningiomas, the most prevalent primary benign intracranial tumors, often exhibit complicated levels of adhesion to adjacent normal tissues, significantly influencing resection and causing postoperative complications. Surgery remains therapeutic approach, when combined with adjuvant radiotherapy, it effectively controls residual tumors reduces tumor recurrence complete removal may cause a neurologic deficit. Previous studies have indicated that slip interface imaging (SII) techniques based...
We conducted a direct comparison of Brain MRE performance between compact, lightweight 3T scanner (C3T) and whole-body (WB3T). demonstrate in phantom volunteers that the C3T provides superior image quality scanning efficiency for commonly performed brain pulse sequences, especially higher-resolution scanning.
This work explored the value of MR elastography (MRE)-measured tumor stiffness and slip interface imaging (SII)-assessed adhesion metrics in predicting extent resection probability meningioma recurrence 52 patients with meningiomas. Tumor percentage was assessed based on pattern recognition normalized octahedral shear strain (NOSS) map. calculated using a neural network-based inversion (NNI). We found that correlates (EOR) possible at surgery, while showed good correlation among aggressive...