A5020601096- Pulmonary Hypertension Research and Treatments
- Peptidase Inhibition and Analysis
- Cardiac tumors and thrombi
- Medical Imaging and Pathology Studies
- Dysphagia Assessment and Management
- Radiomics and Machine Learning in Medical Imaging
- Protease and Inhibitor Mechanisms
- Obstructive Sleep Apnea Research
- Cardiac Structural Anomalies and Repair
- Lung Cancer Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Lung Cancer Treatments and Mutations
- Cardiovascular Function and Risk Factors
- Amphibian and Reptile Biology
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Skin and Cellular Biology Research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- RNA modifications and cancer
- Physiological and biochemical adaptations
- Medical Imaging Techniques and Applications
- Otitis Media and Relapsing Polychondritis
- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- Atomic and Subatomic Physics Research
- Inflammatory Myopathies and Dermatomyositis
Guangzhou Medical University
2015-2025
First Affiliated Hospital of Guangzhou Medical University
2015-2025
First Affiliated Hospital of Xi'an Jiaotong University
2024
State Key Laboratory of Respiratory Disease
2023
Chinese Academy of Agricultural Sciences
2021
Ministry of Agriculture and Rural Affairs
2021
Institute of Crop Sciences
2021
National Cheng Kung University Hospital
2021
Wuxi No.2 People's Hospital
2021
Nanjing Medical University
2021
The purpose of this study was to investigate the feasibility using 18F-labeled fibroblast activation protein inhibitor (FAPI) PET/CT in assessing fibrotic remodeling pulmonary artery (PA) and right ventricle (RV) arterial hypertension (PAH). Methods: In a rat model monocrotaline-induced PAH, rats were euthanized at different time points for tissue analysis (fibroblast immunofluorescence Masson's trichrome staining) after completing 18F-FAPI hemodynamic measurements. Thirty-eight PAH patients...
This study investigates the value of fluorine 18 ([18F])-labeled fibroblast activation protein inhibitor (FAPI) for lymph node (LN) metastases in patients with stage I-IIIA non-small cell lung cancer (NSCLC). From November 2021 to October 2022, 53 NSCLC who underwent radical resection were prospectively included. [18F]-fluorodeoxyglucose (FDG) and [18F]FAPI examinations performed within one week. LN staging was validated using surgical pathological findings. [18F]FDG uptake compared Wilcoxon...
Stroke volume (SV) and cardiac output (CO) were measured in anesthetized larvae of Xenopus laevis from hatching (3 mg) to the end metamorphosis (approximately 1 g). CO SV calculated videotaped images intact beating heart. increased 2.4 x 10(-3) microliters at 3 mg body mass 7.6 g. 0.25 microliter/min 623 microliters/min With use CO, along with arterial pressures another study [P.-C. L. Hou W. Burggren. Am. J. Physiol. 269 (Regulatory Integrative Comp. 38): R1120-R1125, 1995], peripheral...
Metabolic tumor burden (MTB) measurements including metabolic volume and total lesion glycolysis have been shown to prognostic value in non-small-cell lung cancer (NSCLC). The calculation of MTB typically utilizes software semiautomatically draw volumes interest around the tumor, which are subsequently manually adjusted by radiologist include entire tumor. manual adjustment step can be time-consuming observer-dependent. We compared agreement values obtained using semiautomatic method with...
Heart rate and blood pressure were measured in lightly anesthetized developing Xenopus laevis from hatching (body mass approximately 3 mg) to the end of metamorphosis (< or = 1 g). Blood pressures conus arteriosus, truncus ventricle by a servo-null micropressure system. was determined recordings, cardiac cycles videotaped through dissecting microscope. varied 50 150 beats/min showed negative correlation with body mass, slope less than predicted allometric equations based on adult...
The aim of this prospective study was to assess the utility radionuclide salivagram for detecting salivary aspiration in AECOPD patients and evaluate adding value SPECT/CT planar imaging.52 consecutive underwent water swallow test between April 2012 March 2014. All images were interpreted independently by two experienced nuclear medicine physicians. Final diagnosis made consensus readers. results compared using kappa values. relationship exacerbation frequency evaluated with Person χ2...
Immune checkpoint blockade (ICB) therapy using anti-programmed cell death 1 (PD1) and cytotoxic T lymphocyte antigen 4 (CTLA4), either individual or in combination, has emerged as a pioneer clinical immunotherapy for various human cancers. However, immune-related adverse effects (irAEs) remain the significant hindrances to their development. In particular, myocarditis fatal event with highest fatality rate. For this purpose, we report herein first example of uncoupling efficacy toxicity...
Objectives The objective of this study was to test the hypothesis that metabolic tumor volume (MTV) primary non-small-cell lung cancer is not sensitive differences in 18F-fluorodeoxyglucose (18F-FDG) uptake time, and compare consistency MTV measurements with standardized value (SUV) total lesion glycolysis (TLG). Methods Under Institutional Review Board approval, 134 consecutive patients histologically proven underwent 18F-FDG PET/computed tomography scanning at about 1 h (early) 2 (delayed)...
Abstract Background The clinical value of 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) in assessing relapsing polychondritis (RP) with airway involvement remains controversial. This study aimed to investigate PET/CT features RP and explore its predicting disease pattern, severity prognosis. Methods patients who underwent from January 2010 July 2022 were retrospectively reviewed. analyzed both visually semiquantitatively the maximum standardized...
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Pulmonary tumor thrombotic microangiopathy is a malignancy-related complication with rapid progression and high mortality. To improve the understanding of disease, early diagnosis treatment are key to successful treatment. A 39-year-old patient pulmonary hypertension transferred from another hospital was admitted First Affiliated Hospital Guangzhou Medical University on September 26, 2021. The developed shortness breath progressive exacerbation over past month. No artery embolism seen...
Background: Little is known about immediate responses of blood perfusion to the balloon pulmonary angioplasty (BPA) procedure. Objectives: To investigate changes in balloon-dilated vessels and untreated with before, immediately after a single BPA at follow-up. Design: Retrospective single-center cohort study. Methods: Patients who had chronic thromboembolic hypertension (CTEPH) completed photon emission computed tomography (SPECT) imaging follow-up were included. We evaluated defects...
To use radionuclide imaging to investigate silent aspiration among patients recovering from an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We also evaluated the effects exercise-induced dyspnoea on in COPD patients.Recovering AECOPD admitted First Affiliated Hospital Guangzhou Medical University between December 2013 and 2015 were selected for test along with healthy volunteers similar age. Aspiration-negative randomized into two subgroups. Patients group A...