A5081736515- Meta-analysis and systematic reviews
- Pharmaceutical industry and healthcare
- Academic Publishing and Open Access
- scientometrics and bibliometrics research
- Ethics in Clinical Research
- Delphi Technique in Research
- Clinical practice guidelines implementation
- Pneumonia and Respiratory Infections
- Health and Medical Research Impacts
- Emergency and Acute Care Studies
- Health Systems, Economic Evaluations, Quality of Life
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Eosinophilic Esophagitis
- Health Sciences Research and Education
- Biomedical Ethics and Regulation
- Atrial Fibrillation Management and Outcomes
- Antibiotic Use and Resistance
- Asthma and respiratory diseases
- Healthcare Systems and Technology
- FinTech, Crowdfunding, Digital Finance
- Antibiotics Pharmacokinetics and Efficacy
- Biomedical Text Mining and Ontologies
- Gastrointestinal motility and disorders
- Heat shock proteins research
University of Oxford
2023-2025
Oxford Instruments (United Kingdom)
2015-2024
Imperial Consultants
2022
Durham University
2016-2018
Science Oxford
2018
University Hospital of North Tees
2016
University of Aberdeen
2008-2013
MRC Epidemiology Unit
1999
Institute of Philosophy
1927
<h3>Objective:</h3> Existing endoscopy-based data on gastro-oesophageal reflux disease (GORD) in the general population are scarce. This study aimed to evaluate typical symptoms and complications of GORD, their associated risk factors, a representative sample Italian population. <h3>Methods:</h3> 1533 adults from two villages were approached undergo symptom assessment using validated questionnaire upper gastrointestinal endoscopy. Data obtained 1033 individuals (67.4% response rate)....
Background In biomedical research, it is often desirable to seek consensus among individuals who have differing perspectives and experience. This important when evidence emerging, inconsistent, limited, or absent. Even research abundant, clinical recommendations, policy decisions, priority-setting may still require agreement from multiple, sometimes ideologically opposed parties. Despite their prominence influence on key methods are poorly reported. Our aim was develop the first reporting...
Abstract Background Structured, systematic methods to formulate consensus recommendations, such as the Delphi process or nominal group technique, among others, provide opportunity harness knowledge of experts support clinical decision making in areas uncertainty. They are widely used biomedical research, particular where disease characteristics resource limitations mean that high-quality evidence generation is difficult. However, poor reporting reach a – for example, not clearly explaining...
The pharmaceutical industry produces a large proportion of health system greenhouse gas (GHG) emissions, contributing to climate change. This urgently needs be addressed. We aimed examine company change targets, GHG and strategies reduce them. performed content analysis the 20 largest companies' publicly available 2020/2021 reports, focusing on extracting information their reported emissions (and whether companies had demonstrated any reduction in over reporting period), being implemented...
When research evidence is limited, inconsistent, or absent, healthcare decisions and policies need to be based on consensus amongst interested stakeholders. In these processes, the knowledge, experience, expertise of health professionals, researchers, policymakers, public are systematically collected synthesised reach agreed clinical recommendations and/or priorities. However, despite influence exercises, methods used achieve agreement often poorly reported. The ACCORD (ACcurate COnsensus...
Abstract Background In biomedical research, it is often desirable to seek consensus among individuals who have differing perspectives and experience. This important when evidence emerging, inconsistent, limited or absent. Even research abundant, clinical recommendations, policy decisions priority-setting may still require agreement from multiple, sometimes ideologically opposed parties. Despite their prominence influence on key decisions, methods are poorly reported. We aimed develop the...
Plain language summaries of peer-reviewed medical journal publications are a means sharing research with broad range audiences and may improve the transparency, accountability, accessibility, discoverability, inclusivity research. There is currently an ongoing, industry-wide effort to establish consensus on plain summaries, initiatives already in place that provide detailed guidance best practice, co-creation methods, patient-focused content, graphic digital considerations,...
Objectives Authors may choose to work with professional medical writers when writing up their research for publication. We examined the relationship between support and quality timeliness of reporting results randomised controlled trials (RCTs). Design Cross-sectional study. Study sample Primary reports RCTs published in BioMed Central journals from 2000 16 July 2014, subdivided into those (n=110) without (n=123). Main outcome measures Proportion items that were completely reported a...
<i>Background:</i> As new combinations of inhaled corticosteroids (ICSs) and long-acting β<sub>2</sub>-agonists (LABAs) become available for the treatment asthma, it will be important to determine criteria against which they can evaluated. The aim this study was assess attributes combination therapy physicians consider most important. <i>Methods:</i> Primary secondary care asthma specialists (n = 32) were recruited an expert Delphi process that performed...
Academical and not-for-profit research funders are increasingly requiring that the they fund must be published open access, with some insisting on publishing a Creative Commons Attribution (CC BY) licence to allow broadest possible use. We aimed clarify access variants provided by leading medical journals record availability of CC BY for commercially funded research.
Background: When research evidence is limited, inconsistent, or absent, healthcare decisions and policies need to be based on consensus amongst interested stakeholders. In these processes, the knowledge, experience, expertise of health professionals, researchers, policymakers, public are systematically collected synthesised reach agreed clinical recommendations and/or priorities. However, despite influence exercises, methods used achieve agreement often poorly reported. The ACCORD (ACcurate...
Clinical trial sponsors have ethical obligations to register protocols, report study results and comply with applicable legal requirements. To evaluate public commitments disclosure rates of by members non-members the European Federation Pharmaceutical Industries Associations (EFPIA) and/or Research Manufacturers America (PhRMA). Websites top 50 biopharmaceutical companies 2015 sales were searched for statements relating data disclosure. Disclosure completed industry non-industry at least 30...
<ns4:p><ns4:bold>Background</ns4:bold>: In articles reporting randomized controlled trials, professional medical writing support is associated with increased adherence to Consolidated Standards of Reporting Trials (CONSORT). We set out determine whether was also improved CONSORT for Abstracts.</ns4:p><ns4:p><ns4:bold>Methods</ns4:bold>: Using data from a previously published cross-sectional study 463 trials between 2011 and 2014 in five top journals, we determined the association Abstracts...
<ns4:p><ns4:bold>Background</ns4:bold>: In articles reporting randomized controlled trials, professional medical writing support is associated with increased adherence to Consolidated Standards of Reporting Trials (CONSORT). We set out determine whether was also improved CONSORT for Abstracts.</ns4:p><ns4:p><ns4:bold>Methods</ns4:bold>: Using data from a previously published cross-sectional study 463 trials between 2011 and 2014 in five top journals, we determined the association Abstracts...
Purpose: In primary care, initial diagnosis of community-acquired pneumonia (CAP) is made on clinical judgment without radiological confirmation or knowledge the causative organism.Use CRB65 score has been recommended for assessing severity CAP and thereby determining management, but it not known how frequently these scores are used in care.Patients methods: Primary care consultations adults with a diagnostic code between 1 January 2009 31 December 2016 were extracted from Optimum Patient...
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