A5103033567- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Colorectal Cancer Screening and Detection
- Conducting polymers and applications
- Supercapacitor Materials and Fabrication
- Metastasis and carcinoma case studies
- Radiomics and Machine Learning in Medical Imaging
- Antibiotic Resistance in Bacteria
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Cells and Metastasis
- Pancreatic and Hepatic Oncology Research
- Advanced X-ray and CT Imaging
- Stoma care and complications
- Synthesis and properties of polymers
- Antibiotic Use and Resistance
- Thermal Regulation in Medicine
- Fuel Cells and Related Materials
- Cardiac, Anesthesia and Surgical Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hemodynamic Monitoring and Therapy
North Medical Center
2023-2025
Hiroshima City Asa Citizens Hospital
2023-2025
Hiroshima University
2011-2023
University of St. Gallen
2023
Winterthur Museum Garden and Library
2023
Chugoku Rosai Hospital
2023
Higashihiroshima Medical Center
2023
Kure Medical Center
2017-2021
Hiroshima University Hospital
2015-2021
National Hospital Organization
2019-2020
ABSTRACT Background To identify the predictors of local recurrence and distant metastasis after radical surgery for stage I–III colorectal cancer. Materials Methods Patient tumor characteristics, clinicopathological stages, perioperative factors, postoperative outcomes, including recurrence, patients who underwent primary resection were evaluated in this multicenter retrospective analysis. Univariate multivariate regression analyses performed to risk factors recurrences, with a focus on...
Abstract 5‐Fluorouracil (5‐FU) is one of the most frequently used pharmacological agents in treatment colorectal cancer (CRC). Resistance to chemotherapy a major cause failure CRC, and it well known fact that stem cells play significant role acquisition drug resistance. In this study, we focused on KHDRBS3 gene encodes KH RNA Binding Domain Containing, Signal Transduction Associated 3. We first clarified relationship between 5‐FU then observed higher expression levels KRAS‐mutant organoids...
Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. Kinesin Family Member C1 (KIFC1) has been proposed as a promising therapeutic target due to its pivotal role in centrosome clustering mediate cell progression. This study aimed analyze expression and biological function KIFC1 CRC. Immunohistochemically, 67 (52%) 129 CRC cases were positive for statistically associated with poorer overall survival. small interfering RNA (siRNA)-transfected cells...
A microporous silica thin film with low refractive index (low-n) of 1.27 and high Young's modulus 19.5 GPa was obtained by sol−gel synthesis using hydroxyacetone catalyst tetramethyl orthosilicate water in ethanol. Transmission electron microscope images nitrogen adsorption−desorption measurements showed that the pores synthesized were <1 nm diameter. Unlike many other methods, our method did not require sacrificial reagents as templates. This allowed low-temperature fabrication...
The so-called sol-gel technique has been shown to be a template-free, efficient way create functional porous silica materials having uniform micropores. This appears closely linked with postulation that the formation of weakly branched polymer-like aggregates in precursor solution is key micropore generation. However, how such structure can precisely controlled, and further, generated low-fractal dimension imprinted on solid still remain elusive. Here we present fabrication microporous from...
A 9-year surveillance for multidrug-resistant (MDR) Pseudomonas aeruginosa in the Hiroshima region showed that number of isolates harboring metallo-β-lactamase gene bla(IMP-1) abruptly increased after 2004, recorded highest peak 2006, and a tendency to decline afterwards, indicating history an epidemic. PCR mapping variable regions integrons this epidemic was caused by clonal persistence propagation MDR P. strain aminoglycoside 6'-N-acetyltransferase gene, aac(6')-Iae class I integron...
We determined to identify patients with unknown onset stroke who could have favorable 90-day outcomes after low-dose thrombolysis from the THAWS (Thrombolysis for Acute Wake-Up and Unclear-Onset Strokes With Alteplase at 0.6 mg/kg) database.This was a subanalysis of an investigator-initiated, multicenter, randomized, open-label, blinded-end point trial. Patients time last-known-well >4.5 hours showed mismatch between diffusion-weighted imaging (DWI) fluid-attenuated inversion recovery were...
Fully hydrolyzed polyvinyl alcohol (FH-PVA) electrospun fibers with uniform diameters of less than 200 nm were fabricated by reducing the viscosity FH-PVA aqueous solutions. A novel viscosity-modifier (hydrazine monochloride [HMC]) gradually reduced solution over a period several days. This phenomenon is counter to effect usual salt addition. After being stored for days, decreased up 60% compared that an equivalent pure solution. From small angle X-ray scattering (SAXS) and proton nuclear...
Hepatic pseudolymphoma is a very rare benign reactive lymphoid hyperplasia associated with autoimmunity and chronic inflammatory liver diseases such as primary biliary cirrhosis may mimic hepatocellular carcinoma. This diagnosis should be suspected in female suspicious single tumor. Close monitoring needed view of its premalignant nature.
Journal Article Non-invasive measurement of intestinal tissue oxygen saturation for evaluation reconstructed blood flow in rectal cancer surgery: HiSCO-09 study Get access Hisaaki Yoshinaka, Yoshinaka Department Gastroenterological and Transplant Surgery, Graduate School Biomedical Health Sciences, Hiroshima University, Hiroshima, Japan Search other works by this author on: Oxford Academic Google Scholar Manabu Shimomura, Shimomura Correspondence to: 1-2-3, Kasumi, Minami-ku, 734-8551...
Peritoneal metastasis (PM) is detected in 14% of gastric cancers at the time initial diagnosis, with a median survival 4 months. A 66-year-old woman diagnosed cT4a(SE) N2M1(LYN) cStage IV was treated three lines chemotherapy for year. During third line chemotherapy, computed tomography (CT) scan revealed large amount ascites, periportal collar sign, and bilateral ureteral stenosis owing to PM. The tumor biomarkers (CEA CA 19-9) remained elevated similar levels. patient administered 3 mg/kg...
Magnetite cationic liposome (MCL) encapsulating anticancer drug was developed, and the combination effect of hyperthermia chemotherapy evaluated. At first, two drugs which suppress cancer growth by different mechanisms were tested. From this preliminary test, it found that cisdiamminedichloroplatinum (CDDP) enhanced cell killing MCL, but methotrexate (MTX) did not enhance effect. Therefore, similar mechanisms, CDDP or 1- (4-amino-2-methyl-5-pyrimidinyl) -methyl-3- (2-chloroethyl)...
We report 2 cases of ulcerative colitis (UC) with intestinal tract dilatation treated tacrolimus. They were 53- and 64-year-old males, who had been admitted to local hospitals for increasing severity their UC symptoms. Treatment severe was immediately started, but both refractory corticosteroid therapy; they then transferred our hospital. When referred hospital, frequent bloody diarrhea, fever, abdominal pain, even the transverse colon on X-ray test. oral tacrolimus medication, symptoms...
The frequency of small bowel bleeding is relatively low and the process for diagnosis treaVtment remains difficult. Here, we report a case massive due to arteriovenous malformation (AVM), treated by combination double-balloon endoscopy laparoscopic resection.A 59-year-old man was admitted our hospital hemorrhagic stool. patient presented transient shock contrast-enhanced CT revealed hyper-vascularized tumor in bowel. India ink tattooing responsible lesion with performed. tattooed easily...