A5008216380- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Platelet Disorders and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Coagulation and Thrombosis Mechanisms
- Blood properties and coagulation
- Acute Myocardial Infarction Research
- Cardiac Arrhythmias and Treatments
- Hemophilia Treatment and Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Animal Nutrition and Physiology
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pregnancy and preeclampsia studies
- Blood groups and transfusion
- Coronary Interventions and Diagnostics
- Heart Rate Variability and Autonomic Control
- Peripheral Artery Disease Management
- Hemostasis and retained surgical items
- Hemoglobinopathies and Related Disorders
- Erythrocyte Function and Pathophysiology
- Angiogenesis and VEGF in Cancer
- Genetic and phenotypic traits in livestock
- Lipoproteins and Cardiovascular Health
- Cardiac electrophysiology and arrhythmias
Comenius University Bratislava
2016-2025
Martin University Hospital
2015-2024
University of Tehran
2023
Rotunda Hospital
2023
Mater Misericordiae University Hospital
2023
Weatherford College
2021-2022
National Blood Transfusion Service
2018
Martin University
2018
Creative Commons
2017
University Library in Bratislava
2017
Venous thromboembolism (VTE) represents one of the leading causes death during pregnancy. The greatest risk for it is presence medical or family history VTE, stillbirth, cesarean section and selected thrombophilia. Appropriate thromboprophylaxis has potential to decrease VTE in at-risk pregnant patients by 60–70%. Based on this, authors reviewed PubMed, Web Science Scopus databases identify possibilities with a high VTE. Moreover, they summarized its management specific situations, such as...
Background: Impaired endothelial function has been associated with vascular complications in type 2 diabetes (T2D), but its role T2D-related heart failure (HF) remains indeterminate. The aim of this study was to assess selected markers T2D patients acute decompensated HF. Methods: A pilot prospective on HF requiring in-hospital admission carried out. growth factor (VEGF), intercellular adhesion molecule 1 (ICAM-1), and cell (VCAM-1) were assessed at after decongestion. Subsequently,...
Single-nucleotide variants (SNVs) of ABCB1 gene encoding glycoprotein P might be connected with increased or decreased levels direct oral anticoagulants (DOAC), and therefore DOAC-related adverse bleeding embolism. The aim this study was to perform a targeted exome sequencing (TES) in DOAC-treated patients atrial fibrillation, who experienced event (AE) during the therapy. Targeted next generation employed examine SNVs gene, which served as basis for haplotype analysis. enrolled 33 an AE (13...
Proton pump inhibition (PPI) administrated together with dabigatran reduces the risk of gastrointestinal hemorrhage. However, there is a discussion regarding possible PPI-dabigatran interaction that may reduce efficacy this therapy.To determine impact concomitant PPI on plasma levels in patients nonvalvular atrial fibrillation (NV-AF).A pilot prospective study NV-AF therapy was performed; 31 were enrolled. either omeprazole or pantoprazole 19 patients.Blood samples taken for assessment...
Congenital hypofibrinogenemia is a rare bleeding disorder characterized by proportional decrease of functional and antigenic fibrinogen levels. Hypofibrinogenemia can be considered the phenotypic expression heterozygous loss function mutations occurring within one three genes (FGA, FGB, FGG). Clinical manifestations are highly variable; most patients usually asymptomatic, but may appear with mild to severe or thrombotic complications. We have sequenced all exons FGA, FGG using DNA isolated...
Disturbances of coagulation and fibrinolysis in type 2 diabetes mellitus (DM2) contribute to increased rates macrovascular complications such as myocardial infarction ischemic stroke. The aim the study was investigate relationship among plasminogen activator inhibitor 1 (PAI-1), thrombin-activable (TAFI), tissue (t-PA), prothrombin fragments + (F1 2), glycemic control, hypertension, sex body mass index (BMI) DM2 patients with normoalbuminuria microalbuminuria. Forty-two normoalbuminuric...
The purpose of this study was to examine plasma levels fibronectin and plasminogen inhibitor type 1 (PAI-1), alterations in uterine artery (UtA) waveforms throughout normotensive preeclamptic pregnancies analyze its predictive value for the detection preeclampsia within second trimester pregnancy.Blood samples were collected from 102 healthy, nulliparous women between 24th 26th gestational week. Preeclampsia developed 13 patients; 89 control subjects matched same cohort. Plasma assayed PAI-1...
Objective : The purpose of this study was to examine plasma levels fibronectin and plasminogen inhibitor type 1 (PAI-1), alterations in uterine artery (UtA) waveforms throughout normotensive preeclamptic pregnancies analyze its predictive value for the detection preeclampsia within second trimester pregnancy. Material methods Blood samples were collected from 102 healthy, nulliparous women between 24th 26th gestational week. Preeclampsia developed 13 patients; 89 control subjects matched...