- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- Machine Learning in Healthcare
- Pancreatitis Pathology and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Digital Mental Health Interventions
- Gastrointestinal Bleeding Diagnosis and Treatment
- AI in Service Interactions
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 and healthcare impacts
- Misinformation and Its Impacts
- Chronic Disease Management Strategies
- Biomedical Text Mining and Ontologies
- Clinical Reasoning and Diagnostic Skills
- Topic Modeling
- Healthcare cost, quality, practices
- Organ Transplantation Techniques and Outcomes
- Sepsis Diagnosis and Treatment
- Diabetes Treatment and Management
- Health Literacy and Information Accessibility
- Clinical Nutrition and Gastroenterology
- Mental Health via Writing
Juno Therapeutics (Germany)
2025
Monash Health
2015-2024
Monash University
2015-2024
Hologic (Germany)
2022
Australian Regenerative Medicine Institute
2022
Jena University Hospital
2022
Hue Central Hospital
2020-2021
Monash Medical Centre
2016
St Vincent's Hospital
2015
Originally introduced for type 2 diabetes mellitus, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have gained significant market traction the treatment of patients with obesity. There is global heterogeneity across health systems in how these agents are currently used and supplied, which patient cohorts eligible, whom they funded what duration. The deployment GLP-1 RAs obesity has potential to impact one-third Australians. This warrants due consideration planning future funding...
Abstract Chatbots can effect large-scale behaviour change because they are accessible through social media, flexible, scalable, and gather data automatically. Yet research on the feasibility effectiveness of chatbot-administered interventions is sparse. The established when implemented in chatbots not guaranteed, given unique human–machine interaction dynamics. We pilot-tested chatbot-based information provision embedded animations. evaluated whether chatbot could increase understanding...
OBJECTIVES: The diagnosis of cirrhotic ascites is associated with significant morbidity, mortality, and reduced health-related quality life. Adherence by health professionals to indicators (QIs) care for low. We evaluated the effect adherence QIs on clinical outcomes patients hospitalized new onset ascites. METHODS: medical records 302 admitted were interrogated demographic data eight Delphi panel-derived management. Associations between each QI 30-day emergent readmission 90-day mortality...
Background Health literacy is low among patients with chronic liver disease (CLD) and associated poor health outcomes increased care use. Lucy LiverBot, an artificial intelligence chatbot was created by a multidisciplinary team at Monash Health, Australia, to improve self-efficacy in decompensated CLD. Objective The aim of this study explore users’ experience LiverBot using unmoderated, in-person, qualitative test. Methods simple, cost, scalable digital intervention, which the beta prototype...
Abstract Research has been slow to leverage digitalised medical records as a data resource. Our study assessed patient acceptability of opt‐out consent for secondary use digital data. A questionnaire was distributed patients in multiple languages and with an interpreter. Of 919 completed surveys, 33% were non‐English speaking background, 15% self‐reported cognitive impairment 3% refugees. Opt‐out accepted this diverse population; 87% participants approved, or indifferent consent. Gender,...
We conducted a cohort study of adult ward patients who had Medical Emergency Team (MET) call triggered by confirmed or suspected sepsis in an Australian tertiary centre to assess the predictive utility systemic inflammatory response syndrome (SIRS) and quick Sepsis-Related Organ Failure Assessment (qSOFA) scores for 28-day mortality over 12-month period. Sepsis was causative aetiology 970 MET calls 646 with mean age 68 years median Charlson Comorbidity score (CCS) 3.0. Four hundred seven...
Cory COVID-Bot is an artificial intelligence chatbot designed and built by a multisector collaboration to help people safely step towards COVID normal. Achieving normal avoiding unnecessary adverse health outcomes requires effective communication the public regarding safe behaviors, but reaching young, culturally linguistically diverse members of community challenging for government. was developed directly engage with difficult reach populations in English Vietnamese. In order resolve...
The economic burden of decompensated chronic liver disease (CLD) on Australian healthcare services is poorly characterised.To evaluate the in-patient utilisation costs associated with CLD at Monash Health, an tertiary service.The current retrospective cost analysis examined patients admitted between 1 January 2012 and 31 December 2018. Hospitalisations were identified using CLD-specific International Classification Diseases, Tenth Revision, codes. Cost measures estimated Victorian Weighted...
Chronic Hepatitis B (CHB) infection and subsequent liver complications are rising in prevalence Australia due to increased migration from endemic regions. Nearly 50% of all those living with CHB undiagnosed, leading missed opportunities for cancer cirrhosis prevention. Health literacy around among refugee communities such as Afghan, Rohingyan, Sudanese populations (all a high CHB) is low, partly paucity targeted health promotion programmes; despite the release Victorian Strategy (2016-2020)....
Aims. This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores (2) comparing these with SALGIB score in predicting adverse outcomes acute lower gastrointestinal bleeding (ALGIB) a Vietnamese population. Methods. A multicenter cohort was conducted on ALGIB patients admitted to seven hospitals across Vietnam. The consisted blood transfusion; endoscopic, radiologic, or surgical interventions; severe bleeding; in-hospital death. GBS were calculated,...
Chatbots have the potential to effect large-scale behaviour change because they are accessible through social media, flexible, scalable, and automatically gather data. Yet research on feasibility effectiveness of chatbot-administered interventions is sparse. There no guarantee that established effective when implemented in chatbots given unique human-machine interaction dynamics. In this pilot study, we test whether an advanced, natural language processing-based chatbot can using animations...
Abstract Background Mother‐to‐child transmission of hepatitis B virus continues to occur despite universal recommendations for neonatal immune prophylaxis therapy ( IPT ) and infant vaccination. Aim To characterise the risk factors failure provide timely completion vaccination schedule children born mothers with chronic CHB ). Methods We conducted a retrospective cohort study assess compliance guidelines at Monash Health, Australia from 2008 2013. These were invited participate in telephone...
This audit collates data on alcohol-related gastrointestinal (GI) admissions at Monash Health, Victoria, during the prolonged, coronavirus disease 2019 (COVID-19)-related lockdown July to October 2020 compared with same periods in and 2021. We found a 58% increase 16% 2021, which also increased disproportionately overall health service emergency presentations. Self-reported alcohol consumption by 2.5-fold was greatest 2020. Clinical severity unchanged cirrhosis only factor associated severe...
Objective Simultaneous antibody testing during screening for autoimmune conditions is discouraged. The incidence of positive extractable nuclear antigen (ENA) in the setting a negative antinuclear (ANA) has been reported as low. Our objective was to characterize frequency diagnosis new ANA‐associated rheumatic disease (AARD) ANA with ENA. Methods This 7‐year retrospective study from multicenter tertiary health network Australia. Clinical information sought on patients over 18 years old who...
Abstract Background Acute-on-chronic liver failure (ACLF) represents a rising global healthcare burden, characterised by increasing prevalence among patients with decompensated cirrhosis who have 28-day transplantation-free mortality of 33.9%. Due to disease complexity and high socio-economic disadvantage, there are deficits in quality care adherence guideline-based treatment this cohort. Compared other chronic conditions such as heart failure, those reduced access integrated ambulatory...
Abstract Background Ultrasound surveillance for hepatocellular carcinoma (HCC) may improve early tumour detection but additionally result in surveillance‐related harm through increased evaluation of non‐HCC lesions. The incidence these outcomes has not been reported outside North America. Aims We aimed to report the HCC with respect both benefits and harms. Methods reviewed all ultrasounds at a large Victorian tertiary hospital network 2017 followed their until 2021. Surveillance‐related...