- Inflammatory Bowel Disease
- Foreign Body Medical Cases
- COVID-19 and healthcare impacts
- Telemedicine and Telehealth Implementation
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- Esophageal and GI Pathology
- Potassium and Related Disorders
- Healthcare Operations and Scheduling Optimization
- Patient Satisfaction in Healthcare
- Nutrition and Health in Aging
- Blood transfusion and management
- Hematopoietic Stem Cell Transplantation
- Traumatic Ocular and Foreign Body Injuries
- Restraint-Related Deaths
- Blood groups and transfusion
- Chronic Disease Management Strategies
- Clinical Nutrition and Gastroenterology
- Drug-Induced Hepatotoxicity and Protection
- Mental Health Treatment and Access
- Hematological disorders and diagnostics
- Oral and gingival health research
- Smoking Behavior and Cessation
- Obesity, Physical Activity, Diet
Royal Brisbane and Women's Hospital
2024-2025
The University of Queensland
2024-2025
Monash Health
2022-2024
St Vincent's Hospital
2019-2024
QIMR Berghofer Medical Research Institute
2024
The University of Melbourne
2019
The University of Notre Dame Australia
2017
Acute severe ulcerative colitis (ASUC) is a life-threatening medical emergency affecting over 20% of patients with (UC). Up to 40% are refractory intravenous corticosteroids (IVCS) and require rescue therapy or immediate colectomy. The potent Janus kinase (JAK) inhibitors, upadacitinib tofacitinib, have proven efficacy in randomised control trial setting for moderate-to-severe UC, but not ASUC. We describe case series sequential JAK inhibitors following the failure dose-intensified...
Abstract Background Advances in inflammatory bowel disease (IBD) monitoring, greater number of available treatments and a shift towards tight control, IBD care has become more dynamic with regular follow ups. Aims We assessed the impacts COVID‐19 pandemic on outpatient patient at tertiary centre Melbourne. More specifically, we satisfaction telehealth model care, failure to attend rates clinics work absenteeism prior during pandemic. Methods conducted retrospective, qualitative analysis...
Background and study aims Foreign body ingestion is a common cause for Emergency Department presentation. In adults, foreign more in patients with underlying psychiatric comorbidity, the elderly, alcohol intoxication, prisoners. This reviewed management of presenting to tertiary hospital ingestion. Patients methods A retrospective review Melbourne, Victoria, was undertaken from January 2017 December 2021. Data collected included patient demographics, type body, length stay, imaging...
Abstract Background Acute-on-chronic liver failure (ACLF) represents a rising global healthcare burden, characterised by increasing prevalence among patients with decompensated cirrhosis who have 28-day transplantation-free mortality of 33.9%. Due to disease complexity and high socio-economic disadvantage, there are deficits in quality care adherence guideline-based treatment this cohort. Compared other chronic conditions such as heart failure, those reduced access integrated ambulatory...
Summary Background An episode of acute ulcerative colitis (UC) represents an important watershed moment in a patient's disease course. Aims To derive personalised algorithm for identifying patients at high risk corticosteroid non‐response from variables available hospital presentation using large prospectively collected UC patient database and machine learning‐based techniques. Methods We analysed data 682 consecutive presentations UC. used Akaike information criterion‐based elastic net...
Abstract Background Acute Severe Ulcerative Colitis (ASUC) is a life-threatening complication of UC. Previous research has shown that body composition parameters, including sarcopaenia, are associated with outcomes in IBD. However, the relationship between and clinical patients hospitalised ASUC not yet been clearly defined. We sought to further evaluate prognostic role explore predictors outcome ASUC. Methods performed cohort study patients. Body was assessed using fat muscle segmentation,...
We read with interest the article from Zorron Cheng Tao Pu and colleagues on benefits of phone consultation for two hospital-based endoscopy clinics during COVID-19 pandemic.1 The authors demonstrated reduced overall failure to attend rates (FTAs, 6.4% vs 12.6%, P < 0.01) outbreak telephone consultations compared face-to-face in pre-COVID era. Failure is expensive resource demanding, reported FTAs up 30% some centers.2, 3 In Western Australia, 160 000 outpatient appointments were at public...
A 28 year old male was diagnosed with moderate severe colonic and perianal Crohns disease commenced on combination therapy adalimumab azathioprine