Steroid hormones are micropollutants that contaminate the water worldwide and exhibit a significant threat to human health environment even at low concentrations. among most common endocrine disruptors investigated due their widespread use as active ingredients in hormonal treatments natural secretions. Three main types of steroids critical for development multiorgan homeostasis estrogens, progesterone, androgens. The sources steroid livestock excretion, veterinary medicines, agricultural...

We have designed organic ligands able to adsorb on the surface of CdSe−ZnS core−shell quantum dots and switch luminescence inorganic nanoparticles in response hydroxide anions. These compounds incorporate a [1,3]oxazine ring within their molecular skeleton, which reacts with nucleophilic anion generate 4-nitrophenylazophenolate chromophore. The chromogenic transformation activates an energy transfer pathway from dot adsorbed chromophores. As result, intensity coated decreases significantly...

We designed and synthesized an amphiphilic copolymer with pendant hydrophobic decyl hydrophilic poly(ethylene glycol) chains along a common poly(methacrylate) backbone. This macromolecular construct captures boron dipyrromethene fluorophores spiropyran photochromes transfers mixtures of both components in aqueous environments. Within the resulting supramolecular assemblies, retain their photochemical properties switch reversibly to corresponding merocyanine isomers upon ultraviolet...

We synthesized five fluorophore–photochrome dyads designed to switch reversibly between nonfluorescent and fluorescent isomers under optical control. These compounds pair an oxazine photochrome a biphenyl, fluorene, pyrene, coumarin, or cyanine fluorophore in their molecular skeleton can be prepared single step from known precursors yields ranging 30 63%. Nuclear magnetic resonance spectroscopy indicates that the ring of these opens closes spontaneously on millisecond time scale acetonitrile...

Abstract In this study, leaf and frond date palm waste as feedstock was used to derive biochars. The effects of pyrolysis temperatures on their physical chemical properties, capacity remove copper, iron, nickel zinc from single multi-metal solutions at various pH values were investigated. Analytical spectroscopic techniques such scanning electron microscopy, energy dispersive X-ray, Fourier transform infrared spectroscopy, X-ray diffraction, carbon, hydrogen, nitrogen, sulfur elemental...

This study investigates the removal of manganese and nitrate from aqueous systems in batch column studies using date palm waste-derived biochar. High efficiencies adsorption capacities (73.20%, qe: 3.57 mg/g for 94.94%, 4.18 nitrate) were attained at pH 6 with a dosage 0.1 g biochar derived 50/50% mixture leaves fronds pyrolyzed 500°C. The equilibrium data fits well to Freundlich Langmuir isotherm models respectively R2=1. model dictates that biochar's surface is heterogeneous, can occur...

Abstract Peptides have become an indispensable tool in engineering of multifunctional nanostructure platforms for biomedical applications such as targeted drug and gene delivery, imaging biosensing. They can be covalently incorporated into a variety nanoparticles (NPs) including polymers, metallic nanoparticles, others. Using different bioconjugation techniques, peptide‐modified NPs formulated to produce therapeutical diagnostic offering high specificity, lower toxicity, biocompatibility,...

Semiconductor quantum dots are becoming valuable analytical tools for biomedical applications. Indeed, their unique photophysical properties offer the opportunity to design luminescent probes imaging and sensing with unprecedented performance. In this context, we have identified operating principles transduce supramolecular association of complementary receptor-substrate pairs into an enhancement in luminescence sensitive dots. Our mechanism is based on electrostatic adsorption cationic...

We developed a strategy to switch the luminescence of semiconductor quantum dots with chemical stimulations. It is based on photoinduced transfer either energy from CdSe-ZnS core-shell [1,3]oxazine ligands or electrons organic inorganic components. The incorporate dithiolane anchoring group, an electron-rich indole, and 4-nitrophenylazophenoxy chromophore in their molecular skeleton. Their adsorption surface results partial quenching. Electron indole fragment nanoparticles mainly responsible...

We designed four polymeric ligands for semiconductor quantum dots and synthesized these macromolecular constructs in steps, starting from commercial precursors. These have a poly(methacrylate) backbone with pendant thiol groups poly(ethylene glycol) chains. The anchor on the surface of preformed CdSe-ZnS core-shell dots, chains impose hydrophilic character resulting assemblies. Indeed, three sets are soluble aqueous environments stable under conditions days over wide pH range (5.0-9.0)....

The development of multifunctional nanoparticles for medical applications is growing technological interest. A single formulation containing imaging and/or drug moieties that also capable preferential uptake in specific cells would greatly enhance diagnostics and treatments. There interest plant-derived viral (VNPs) establishing new platform technologies based on these inspired by nature. Cowpea mosaic virus (CPMV) serves as the standard model VNPs. Although exterior surface modification...

We synthesized macromolecular ligands for CdSe−ZnS core−shell quantum dots incorporating multiple thiol groups, poly(ethylene glycol) chains, and either carboxylic acids or primary amines along a common poly(methacrylate) backbone. The groups encourage the adsorption of these constructs on ZnS shell nanoparticles, chains impose hydrophilic character resulting assemblies. Indeed, coated are readily soluble in water stable under conditions months over broad pH range (4.0−12.0) even presence...

Nanomaterial-based carrier systems hold great promise to deliver therapies with increased efficacy and reduced side effects. While the state-of-the-art system is a sphere, recent data indicate that elongated rods filaments have advantageous flow margination properties, resulting in enhanced vascular targeting tumor homing. Here, we report on distinct diffusion rates of two bio-inspired systems: 30 nm-sized spherical cowpea mosaic virus (CPMV) 300 × 18 tobacco (TMV) tubular structure, using...

Highly luminescent, water-soluble and biocompatible Carbon Quantum Dots (aqCQDs) were prepared by encapsulating the parent hydrophobic CQDs in an amphiphilic polymer. The resulting aqCQDs non-toxic to living cells, found cross cell membrane localise primarily cytosol.

Abstract In recent years, nanoparticle formulations utilizing magnetic materials have started gaining more consideration in the biomedical arena due to their inherent superparamagnetic/paramagnetic nature paving ways develop assays and sensors benefitting mostly separation technique. Coupled with developments synthetic field obtaining controlled-sized particles surface functionalities, a variety of sensitive selective been developed ranging from detection/separation/enrichment antibodies,...

Viral nanoparticles (VNPs) based on plant viruses such as Cowpea mosaic virus (CPMV) can be used for a broad range of biomedical applications because they present robust scaffold that allows functionalization by chemical conjugation and genetic modification, thereby offering an efficient drug delivery platform target specific cells tissues. VNPs CPMV show natural affinity to cells; however, cellular uptake is inefficient. Here we modification the surface with highly reactive, UV-traceable...