A5091848787- Spinal Fractures and Fixation Techniques
- Meningioma and schwannoma management
- Intracranial Aneurysms: Treatment and Complications
- Spine and Intervertebral Disc Pathology
- Epilepsy research and treatment
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Spinal Dysraphism and Malformations
- Neuroscience and Neuropharmacology Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Craniofacial Disorders and Treatments
- Cervical and Thoracic Myelopathy
- Fetal and Pediatric Neurological Disorders
- Trigeminal Neuralgia and Treatments
- Trauma Management and Diagnosis
- Pharmacological Effects and Toxicity Studies
- Facial Nerve Paralysis Treatment and Research
- Neurofibromatosis and Schwannoma Cases
- Management of metastatic bone disease
- Pituitary Gland Disorders and Treatments
- Advanced Neuroimaging Techniques and Applications
- Neurosurgical Procedures and Complications
- Pelvic and Acetabular Injuries
Universidade Estadual de Campinas (UNICAMP)
2015-2024
Centro Infantil Boldrini
2017-2024
Brazilian Institute of Neuroscience and Neurotechnology
2000-2024
Hospital de Clínicas da Unicamp
2008-2024
Creative Research Enterprises (United States)
2017
Centro Universitário da Cidade
2013
Universidade Federal de Lavras
2010
Neurological Surgery
1992-2008
Florida College
1992-2008
University of Florida
1992-2008
We review the anatomy of mesial temporal lobe region, establishing relationships among intraventricular, extraventricular, and surrounding vascular structures their angiographic characterization. also demonstrate clinical application these anatomic landmarks in an lobectomy plus amygdalohippocampectomy.Fifty-two adult cadaveric hemispheres 12 heads were studied, using a magnification ranging from 3x to 40x, after perfusion arteries veins with colored latex.The intraventricular elements are...
Abstract Background Previous research in animal seizure models indicates that the pleiotropic cytokine TNF is an important effector/mediator of neuroinflammation and cell death. Recently, it has been demonstrated downregulates Klotho (KL) through nuclear factor kappa B (NFkB) system chronic kidney disease colitis. KL function brain unclear, although knockout ( Kl −/− ) mice exhibit neural degeneration a reduction hippocampal synapses. Our aim was to verify if triad - NFKB1 also dysregulated...
The reasons for surgical failure in 30% of patients with unilateral mesial temporal lobe epilepsy (MTLE) are still unclear. We investigated if different outcomes could be associated to patterns subtle gray matter atrophy (GMA) and white (WMA), searched postoperative magnetic resonance imaging (MRI) changes.We studied 69 controls 67 operated refractory MTLE. Patients were grouped as seizure-free (SF) group (34 Engel's IA), worthwhile improvement (23 patients, IB-IIA) (10 IIB-IV). created a...
Most of the craniometric relationships normal craniocervical junction (CCJ), especially those related to angular craniometry, are still poorly studied and based on measurements taken from simple plain radiographs. In this study, authors performed a evaluation CCJ in population without known anomalies. The purpose study was evaluate craniometry obtained CT scans.The analyzed 100 consecutive scans adult patients who were admitted at their tertiary hospital for treatment non-CCJ conditions...
OBJECTIVE: To illustrate in a stepwise fashion the microsurgical anatomy of transcavernous approach to interpeduncular and prepontine cisterns discuss our initial results with 15 basilar tip aneurysms managed through that approach. METHODS: Using 10 embalmed cadaveric heads perfused colored silicon, we performed bilateral dissections via an orbitozygomatic pretemporal craniotomy. Measurements exposure artery obtained along dorsum sellae upper clivus were taken. Our clinical data derived from...
The authors present a surgical approach that incorporates the frontal sinus and extends supraorbital craniotomy to include lateral orbital rim zygoma. provides wide exposure of anterior fossa, orbit, ipsilateral middle cavernous sinus. procedure can be performed easily, bone flaps secured rapidly back into anatomical position at time closure. This modified is ideal for large benign lesions originating along sphenoid wing or orbit expand fossa.
Surgical removal of the hippocampus is standard care patients with drug-resistant medial temporal lobe epilepsy (MTLE). The procedure carries a success rate approximately 75%, but reasons that some fail to achieve seizure control after surgery remain inexplicable. question whether resection structures in addition would influence surgical outcome MTLE was examined.We conducted voxel-based statistical analyses postoperative high-resolution MRI who underwent anteromedial resection. We applied...
The Thoracolumbar Injury Classification and Severity Score (TLICS) was developed to improve injury classification guide surgical decision making, yet validation remains necessary. This study evaluates the neurological outcome of patients with thoracolumbar spine trauma (TLST) treated according TLICS.The TLICS prospectively applied a consecutive series for TLST between 2009 2012. Patients 4 points or more were surgically treated, whereas 3 fewer conservatively managed. primary American Spinal...
To assess the validity of an online method to quantitatively evaluate cerebral hypometabolism in patients with pharmacoresistant focal epilepsy as a complement visual analysis 18F-FDG positron emission tomography (PET)/CT exam.A total 39 and probable cortical dysplasia [22 frontal lobe (FLE) 17 temporal (TLE)] underwent presurgical evaluation including EEG, video-EEG, MRI, PET/CT. We conducted automated quantification their PET/CT data compared results those visual-PET by experienced nuclear...
OBJECTIVE The authors evaluated a new classification for subaxial cervical spine trauma (SCST) recently proposed by the AOSpine group based on morphological criteria obtained using CT imaging. METHODS Patients with SCST treated at authors' institution according to Subaxial Cervical Spine Injury Classification system were included. Five different blinded researchers classified patients' injuries imaging 2 times (4-week interval between each assessment). Reliability was assessed kappa index...
Introduction Focal cortical dysplasia (FCD) is a common cause of pharmacoresistant epilepsy. According to the 2022 International League Against Epilepsy classification, FCD type II characterized by dysmorphic neurons (IIa and IIb) may be associated with balloon cells (IIb). We present multicentric study evaluate transcriptomes gray white matters surgical specimens. aimed contribute pathophysiology tissue characterization. Methods investigated (a b) control samples performing RNA-sequencing...
OBJECTIVE Persistent primitive carotid-basilar artery anastomoses are uncommon, and usually seen on an angiogram or discovered at autopsy. The most frequent type of anastomosis is the persistent trigeminal artery. METHODS A single case a medial variation artery, as in well-preserved human adult anatomic specimen injected with red latex, presented, anatomy this uncommon discussed. RESULTS This unique its clear preservation which arises from portion right intracavernous carotid gives rise to...
OBJECT Hemangioblastomas are rare, benign, highly vascularized tumors that can be found throughout the neuraxis but mainly located in cerebellum and spinal cord. Spinal hemangioblastomas present with motor sensory deficits, whose severity varies according to size location of tumor. Resection is best treatment option avoid neurological deterioration. The authors report surgical results intramedullary discuss technical nuances important achieving total resection without adding new deficits....