A5100360979- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Advanced MRI Techniques and Applications
- EEG and Brain-Computer Interfaces
- Neurological disorders and treatments
- Functional Brain Connectivity Studies
- Neonatal and fetal brain pathology
- Fetal and Pediatric Neurological Disorders
- Quality and Supply Management
- Genetics and Neurodevelopmental Disorders
- Advanced Neuroimaging Techniques and Applications
- Systemic Lupus Erythematosus Research
- Cerebrovascular and Carotid Artery Diseases
- Cerebrospinal fluid and hydrocephalus
- Genetic Neurodegenerative Diseases
- Hemoglobinopathies and Related Disorders
- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Mitochondrial Function and Pathology
- Infectious Encephalopathies and Encephalitis
- Multiple Sclerosis Research Studies
- Psychosomatic Disorders and Their Treatments
- Parasitic infections in humans and animals
- Peripheral Neuropathies and Disorders
First Affiliated Hospital of Xinjiang Medical University
2025
Xinjiang Uygur Autonomous Region Disease Prevention and Control Center
2025
Shandong University of Traditional Chinese Medicine
2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2025
Xinjiang Medical University
2025
Nanjing University
2025
Shandong Normal University
2024
Chengdu University of Traditional Chinese Medicine
2024
Shanghai Jinyuan Senior High School
2024
Thermal Power Research Institute
2023
Background The temporal and insular cortex (TC, IC) have been associated with autonomic nervous system (ANS) control the awareness of emotional feelings from body. Evidence shows that ANS rating perceived exertion (RPE) regulate exercise performance. Non-invasive brain stimulation can modulate cortical area directly beneath electrode related to RPE, but it could also affect subcortical areas by connection within cortico-cortical neural networks. This study evaluated effects transcranial...
Whether temporal lobe epilepsy is the result of an isolated, early injury or whether there ongoing neuronal dysfunction loss due to seizures often debated. We attempt address this issue by using magnetic resonance techniques. Proton spectroscopic imaging can detect and quantify focal based on reduced signals from marker N-acetylaspartate (NAA), (MRI)-based measurements hippocampal volumes (MRIvol) amount atrophy in structure. performed MRIvol 82 consecutive patients with medically...
High-resolution MRI can detect dual pathology (an extrahippocampal lesion plus hippocampal atrophy) in about 5–20% of patients with refractory partial epilepsy referred for surgical evaluation. We report the results 41 interventions 38 adults (mean age 31 years, range 14–63 years) pathology. Three had two operations. The mean postoperative follow-up was 37 months (range 12–180 months). lesions were cortical dysgenesis 15, tumour 10, contusion/infarct eight and vascular malformation five...
Conventional volumetric studies have shown that brain structures functionally and anatomically related to the hippocampus are smaller in patients with drug-refractory medial temporal lobe epilepsy (MTLE).To determine extent of gray matter atrophy brains MTLE examine pattern atrophy.We performed a voxel-based morphometric study 43 consecutive unilateral (21 right-sided 22 left-sided MTLE) whose magnetic resonance images showed signs hippocampal atrophy. The data from were compared 49 healthy...
Background: It is unclear which factors lead to progressive neuronal damage in mesial temporal lobe epilepsy (MTLE). The objective of this study was evaluate whether hippocampal and extrahippocampal atrophy occur patients with MTLE related seizures. Method: We performed 2 MRI scans 33 clinical electroencephalographic diagnosis 24 healthy controls. a 2-T scanner, T1-weighted gradient-echo sequence 1 mm thickness used for voxel-based morphometry analysis. Follow-up images were obtained at...
OBJECTIVE Inflammation and dysfunction of the hypothalamus are common features experimental obesity. However, it is unknown whether obesity massive loss body mass can modify immunologic status or functional activity human brain. Therefore, aim this study was to determine effect reduction on brain functionality. RESEARCH DESIGN AND METHODS In humans, changes in hypothalamic after a meal glucose intake be detected by magnetic resonance imaging (fMRI). Distinct fMRI analytic methods have been...
Abstract We describe 5 women and men with periventricular nodular heterotopia electroclinical features suggestive of temporal lobe epilepsy, who were surgically treated for control medically refractory seizures. Magnetic resonance imaging revealed bilateral in 7 the 10 patients. Because lack clear localization, 6 patients studied intracranial depth electrode recordings. Seizures hippocampal onset (3 patients), regional (2 or occipital‐temporal (1 patient). Anterior lobectomy was performed...
The worldwide prevalence of epilepsy is variable, estimated at 10//1,000 people, and access to treatment also variable. Many people go untreated, particularly in resource-poor countries. To estimate the proportion not receiving adequate different socioeconomic classes Brazil, a country. A door-to-door survey was conducted assess gap three areas two towns Southeast Brazil with total population 96,300 people. validated screening questionnaire for (sensitivity 95.8%, specificity 97.8%) used....
In the past underlying structural abnormalities leading to development of chronic seizure disorders have usually only been disclosed by histological examination surgical or postmortem material, due their often subtle nature that was beyond resolution CT early MRI. The MRI findings in 341 patients with chronic, refractory epilepsy attending National Hospital for Neurology and Neurosurgery Chalfont Centre Epilepsy are reported. Studies were performed on a 1.5 Tesla scanner specific volumetric...
The mechanisms guiding the progression of neuronal damage in patients with Huntington disease (HD) are not completely understood. It is unclear whether genotype--that is, length expanded CAG repeat--guides location and speed grey matter decline once HD clinically manifested. Moreover, relationship between cortical subcortical atrophy severity motor symptoms controversial.In this article, we longitudinally studied, over period 1 year, a cohort 49 HD. We investigated: first, clinical relevance...
Abstract Objective To determine cerebral and corpus callosum volumes in patients with systemic lupus erythematosus (SLE), using semiautomatic magnetic resonance imaging (MRI) volumetric measurements, to possible relationships between a reduction volume disease duration, total corticosteroid dose, neuropsychiatric manifestations, the presence of antiphospholipid antibodies. Methods We studied 115 consecutive SLE 44 healthy volunteers. A complete clinical, laboratory, neurologic evaluation was...
<b>Objectives:</b> To determine the frequency and progression of hippocampal atrophy in systemic lupus erythematosus (SLE) clinical, laboratory treatment features associated with its occurrence. <b>Methods:</b> 150 patients SLE 40 healthy volunteers were enrolled our study. A complete neurological evaluation was performed. Magnetic resonance imaging carried out using a 2T scanner (Elscint Prestige) coronal T1-weighted images used for manual volumetric measurements. Atrophy defined as values...
<b>Background:</b> Structural neuroimaging studies have consistently shown a pattern of extra-hippocampal atrophy in patients with left and right drug-refractory medial temporal lobe epilepsy (MTLE). However, it is not yet completely understood how related to hippocampal atrophy. Moreover, MTLE often exhibit more intense cognitive impairment, subtle brain asymmetries been reported versus but explored controlled study. <b>Objectives:</b> To investigate the association between MTLE, effect...
Abstract Objective To analyze the clinical significance of hyperintense white matter (WM) lesions in both symptomatic and asymptomatic systemic lupus erythematosus (SLE) patients. Methods We studied 120 consecutive SLE patients 44 healthy volunteers. Fluid attenuated inversion recovery T2‐weighted magnetic resonance images (MRI) were used for visual semiautomatic volumetric measurements. Results At baseline, 61 MRI normal 59 had WM lesions. Mean volumes 96.14 (SD = 85.14) mm 3 T2 weighted...
Background/aim Currently, the equipment and techniques available to assess brain function during dynamic exercise are limited, which has restricted our knowledge of how regulates exercise. This study assessed areas activated cycling by making use a novel cycle ergometer, constructed measure functional MRI (fMRI) images Furthermore, we compared activation at different levels ratings perceived exertion (RPE) generated Methods Seven healthy adults performed in compatible ergometer while...
To investigate the presence of hippocampal atrophy (HA) and other magnetic resonance imaging (MRI) signs sclerosis (HS) in asymptomatic relatives patients with familial mesial temporal lobe epilepsy (FMTLE).We invited first-degree, FMTLE to participate our MRI protocol. After obtaining informed consent, all participating individuals underwent an examination. Hippocampal abnormality was determined by qualitative volumetric analyses, using a standard protocol.We studied 52 (27 men), mean age...
PURPOSE: To validate a Stigma Scale of Epilepsy (SSE). METHODS: The SSE was completed by 40 adult with epilepsy attending an Outpatient Clinic at the University Hospital UNICAMP, and people from community. People were interviewed on individual basis; psychologist read questions to subjects who wrote answers in sheet. procedure same for all completion took around ten minutes. RESULTS: has 24 items. internal consistency showed alpha Cronbach’s coefficient 0.88 patients 0.81 overall mean scores...