BackgroundThere are several options available for conservative treatment of partial-thickness burns, however, reliable, affordable, and easily obtainable animal testing models hard to find the comparison different methods. We aimed at developing a preclinical model comparing four methods superficial burns.MethodsBurn injury was induced in 90 adult male Wistar rats by placing 130°C hot tip commercially soldering device 30 s on clipped skin interscapular region steady pressure. Skin histology...

Background: Pediatric olecranon fractures, which involve a break in the bony prominence of elbow, are relatively rare but can be serious. Treatment options typically depend on type and severity fracture. Displaced, intraarticular fractures require surgical intervention, where resorbable implants becoming promising alternative to traditional metal hardware. Methods: Our prospective, single-center, single-arm case series evaluates three pediatric fracture patients treated by...

Background: Pediatric diaphyseal forearm fractures, often caused by sports or leisure activities, require treatment based on fracture stability. While stable fractures can be managed conservatively, unstable typically surgery, with elastic intramedullary (IM) nailing (ESIN) being the gold standard. Bioabsorbable IM nails (BINs) offer an alternative eliminating need for implant removal surgery. Methods: Between May 2023 and January 2025 we consecutively 161 children poly-L-lactic-co-glycolic...

Background: Pediatric olecranon fractures, though rare, can be serious. Treatment varies by type and severity; displaced, intraarticular fractures usually need surgery, where biodegradable implants are emerging as an encouraging option to metal hardware. Methods: Our prospective, single-center, single-arm case series evaluates three pediatric fracture patients treated resorbable poly-L-lactic-co-glycolic acid (PLGA) pins polydioxanone (PDS) loops between Jan 2022 January 2023 at the...

Coronoid process fractures in the pediatric population are rare and often misdiagnosed, leading to chronic elbow instability. We aim evaluate surgical management of two adolescent cases inveterate coronoid using autologous bone grafting. Both patients, with a history recurrent dislocations, presented pseudoarthrosis were initially misdiagnosed due minor or subtle fractures. Comprehensive imaging, including computed tomography (CT) magnetic resonance imaging (MRI), confirmed presence...

Background: Syndactyly, the congenital fusion of digits, compromises hand function and esthetics. Although surgical separation is standard treatment, optimal timing intervention remains controversial. Methods: We prospectively analyzed 20 pediatric patients (86 operated fingers) undergoing syndactyly repair, comparing early (≤24 months) versus delayed (>24 surgery. Outcome measures included range motion (ROM) at metacarpophalangeal (MP), proximal interphalangeal (PIP), distal (DIP)...

Background: Pediatric diaphyseal forearm fractures, often caused by sports or leisure activities, require treatment based on fracture stability. While stable fractures can be managed conservatively, unstable typically surgery, with elastic intramedullary (IM) nailing (ESIN) being the gold standard. Bioabsorbable IM nails (BINs) offer an alternative eliminating need for implant removal surgery. Methods: Between May 2023 and January 2025, we consecutively 161 children poly-L-lactic-co-glycolic...

Abstract Background Distal radius fractures are very common in paediatric patients. Severely displaced may require surgical intervention. The gold standard method is percutaneous K-wire osteosynthesis followed by immobilisation. Metal implants can be removed with a second intervention; however, these extra procedures cause further complications. Several studies confirm the benefits of bioabsorbable for aim this retrospective study was to compare complication rates distal metaphyseal (AO...

The incidence of articular injury, particularly osteochondral fractures (OCFs), has seen a cinnotable increase in recent years. Regardless their location, fragments can be overlooked by plain radiographs, which might lead to osteoarthritis the long run. Diagnostic imaging pivotal role assessment and classification fracture severity, as well presence any associated dislocations. These require surgical intervention for restoration joint function reduction long-term complications. This paper...

Pediatric forearm fractures, particularly involving the shaft or diaphysis, are common injuries typically resulting from accidental trauma during various activities. Traditional treatment involves closed reduction and casting; however, surgical intervention may be necessary in certain cases. The gold standard approach utilizes elastic stable intramedullary nailing (ESIN), but a newer technique uses bioabsorbable nails made of poly(lactic-co-glycolic acid) (PLGA). This study aims to compare...

Rationale: Short double elastic nailing is a minimal invasive, modified ESIN (elastic stable intramedullary nailing) technique for severely displaced distal radial fracture in children. The aim of this technical report to introduce our new method and evaluate the final results procedure. Patient concerns: We reviewed retrospectively 24 patients who underwent short due fractures between November 2012 December 2015. Indications surgery included closed, displaced, unstable metaphyseal or...

(1) Background: Diaphyseal forearm fractures are a common injury in children and adolescents. When operative treatment is needed, elastic stable intramedullary nailing (ESIN) the most surgical procedure. Although there no clear evidence, hardware removal after fracture healing performed many patients. Often, primary minimal invasive incision needs to be widened during implant removal. In order decrease burden of care pediatric fractures, significant efforts were made develop biodegradable...

Background: Pediatric forearm fractures represent a substantial proportion of childhood injuries, requiring effective and minimally invasive treatments. Our study investigated the mid-term outcomes biodegradable poly-L-lactide-co-glycolide (PLGA) intramedullary implants in managing diaphyseal children. Methods: A follow-up cohort was conducted with 38 patients treated PLGA implants. Control examinations were performed one year post-operation, assessing bone healing through radiographic...

Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with diverse developmental roles, including differentiation of skeletal elements. It positive regulatory factor chondrogenesis and osteogenic in vitro, but little known about its vivo role bone formation. In our experiments, diaphyses long bones from hind limbs PACAP gene-deficient mice showed changes thickness increased staining intensity. Our main goal was to perform detailed morphological molecular biological...

Burns is a common type of traumatic injury in childhood. Nowadays, several wound dressings are available to treat the second-degree hand burns conservatively.At authors' institute, 37 children were treated conservatively with special dressing at first intervention containing Aquacel Ag foam and Zn-hyaluronic gel determine their effectiveness on partial thickness burns.The was checked second day, removed sixth or seventh day (unless it had spontaneously separated).None this diagnosed...

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a naturally secreted signaling peptide and has important regulatory roles in the differentiation of central nervous system its absence results disorders femur development. PACAP an function prevention oxidative stress or mechanical chondrogenesis but little known about bone regeneration. A new callus formation model was set to investigate role remodeling. Fracturing 5 mm distal from proximal articular surface tibia depth 0.5 mm....

Abstract Unstable distal metaphyseal and dia-metaphyseal fractures of the radius may have treated with a variety operative techniques, Kirschner wires (K-wires), dorsally inserted titanium elastic stable intramedullary nailing (DESIN), short (SESIN) in children. The aim this study was to evaluate differences clinical radiographic outcomes between these methods. Between January 2009 December 2017 196 children were for forearm third radius. Gender patients, different types surgical number...

In pediatric burn care, achieving swift healing with minimal complications remains paramount. This investigation assesses polyhexamethylene biguanide (PHMB)'s role in managing superficial partial-thickness burns children, focusing on the effects of various patient-specific factors recovery. Through a retrospective analysis 27 cases treated PHMB, we explored impact age, size, dressing frequency, treatment delay, cold therapy application, and analgesic usage duration until...