- Diet and metabolism studies
- Nutritional Studies and Diet
- Eating Disorders and Behaviors
- Dietary Effects on Health
- Clinical Nutrition and Gastroenterology
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Sirtuins and Resveratrol in Medicine
- Gut microbiota and health
- Pain Management and Placebo Effect
- Circadian rhythm and melatonin
- Adipose Tissue and Metabolism
- Bariatric Surgery and Outcomes
- Gestational Diabetes Research and Management
- Consumer Attitudes and Food Labeling
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- Mindfulness and Compassion Interventions
- Obesity and Health Practices
- Liver Disease Diagnosis and Treatment
- Biochemical effects in animals
- Machine Learning in Healthcare
- Cardiac Health and Mental Health
- Phytochemicals and Antioxidant Activities
- Calcium signaling and nucleotide metabolism
University of Turin
2015-2024
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino
2022
Our aim is evaluating the changes in weight and dietary habits a sample of outpatients with obesity after 1 month enforced lockdown during COVID-19 pandemic Northern Italy. In this observational retrospective study, patients our Obesity Unit were invited to answer 12-question multiple-choice questionnaire relative changes, working activity, exercise, habits, conditions potentially impacting on nutritional choices. A multivariate regression analysis was performed evaluate associations among...
Gestational diabetes mellitus (GDM), a common pregnancy complication, is associated with an increased risk of maternal/perinatal outcomes. We performed prospective observational explorative study in 41 GDM patients to evaluate their microbiota changes during and the associations between gut variations nutrient intakes, anthropometric laboratory variables. routinely received nutritional recommendations according guidelines. The fecal (by 16S amplicon-based sequencing), was assessed at...
The chatbot Chat Generative Pretrained Transformer (ChatGPT) is becoming increasingly popular among patients for searching health-related information. Prior studies have raised concerns regarding accuracy in offering nutritional advice. We investigated November 2023 ChatGPT's potential as a tool providing guidance relation to different non-communicable diseases (NCDs). First, the dietary advice given by ChatGPT (version 3.5) various NCDs was compared with guidelines; then, chatbot's capacity...
Orthorexia and muscle dysmorphia are disorders affecting above all young adults whose prevalence social impact still unclear. We aimed to evaluate the of traits orthorexia among freshmen attending university courses focused on nutrition (Dietetics) body care (Exercise Sport Sciences). Students Biology were considered as a control group. The eating disorder (ED) also evaluated.All participants (n = 440; n 53 Dietetics school, 200 Exercise Sciences 187 school) completed following...
The cardio-protective effects of flavonoids are still controversial; many studies referred to the benefits specific foods, such as soy, cocoa, tea. A population-based cohort middle-aged adults, coming from a semi-rural area where consumption those foods is almost negligible, was studied. primary objective establishing if flavonoid intake inversely associated with cardiovascular (CV) risk evaluated after 12-year follow-up; associations between and CV incidence mortality all-cause were also...
Abstract Aims Sirtuin-1 (SIRT-1) down-regulation in type 2 diabetes mellitus (T2DM) has been associated with epigenetic markers of oxidative stress. We herein aim to evaluate whether an increase SIRT-1 expression affects histone 3 acetylation at the 56 lysine residue (H3K56ac) T2DM patients randomly selected receive either resveratrol (40 mg or 500 mg) a placebo for 6 months. The primary outcome is changes H3K56ac level by variation and secondary evidence association between level,...
The microbiota composition of the offspring women with gestational diabetes mellitus (GDM), a common pregnancy complication, is still little known. We investigated whether GDM gut associated maternal nutritional habits, metabolic variables or outcomes. Furthermore, we compared to normoglycemic-mother offspring. Fecal samples 29 infants were collected during first week life and assessed by 16S amplicon-based sequencing. offspring's showed significantly lower α-diversity than corresponding...
Abstract Objectives Patients with type 2 diabetes (T2DM) are at increased fracture risk. Resveratrol has shown beneficial effects on bone health in few studies. The aim of this trial was to investigate the resveratrol mineral density (BMD) and calcium metabolism biomarkers T2DM patients. Methods In double-blind randomized placebo-controlled 192 outpatients were receive 500 mg/day (Resv500 arm), 40 (Resv40 arm) or placebo for 6 months. BMD, content (BMC), serum calcium, phosphorus, alkaline...
The aim of this observational study was investigating the possible correlation between adherence to Mediterranean diet (MeD) and SARS-COV-2 infection rates severity among healthcare professionals (HCPs). An online self-administrated questionnaire (evaluating both MeD dietary habits) filled out by HCPs working in Piedmont (Northern Italy) from 15 January 28 February 2021. Out 1206 questionnaires collected, 900 were considered reliable analyzed. Individuals who reported (n = 148) showed a...
The metabolic benefits of time-restricted eating (TRE) in humans are statistically significant but not clinically relevant. Few data available about the effects TRE on gut microbiota. We compared a regimen (<12 h feeding; n = 25) with time-unrestricted (TUE) (>12 24), clinical and dietary variables gut-microbiota composition patients obesity, who were subjected for 12 weeks to same caloric restriction. Median weight loss was 4.0 kg 2.2 TUE groups, respectively, between-group borderline...
Abstract Background Obesity is the result of energy intake (EI) chronically exceeding expenditure. However, potential metabolic factors, including insulin resistance, remain unclear. This study longitudinally investigated factors associated with changes in body weight. Subjects A cohort 707 adults without diabetes were at 4-year follow-up visit. The habitual and macronutrients during past 12 months was assessed using a validated Food Frequency Questionnaire for local population. Homeostatic...
Adherence to the Mediterranean diet reduces risk of all-cause and cardiovascular (CV) mortality incidence CV events. However, most previous studies were performed in high-risk individuals. Our objective was assess whether adherence diet, evaluated by MED score, associated with events individuals at low from a population-based cohort, after 12-year mean follow-up. A cohort 1658 completed validated food-frequency questionnaire 2001–2003. The score calculated 0–9 scale. Anthropometric,...
In patients with obesity, micronutrient deficiencies have been reported both before and after bariatric surgery (BS). Obesity is a chronic pro-inflammatory status, inflammation increases the risk of malnutrition. Our objective was to assess in pre-BS prevalence their correlation blood values C-reactive protein (CRP).Anthropometric data, instrumental examinations, variables were centrally measured first 200 undergoing evaluation at "Città della Salute e Scienza" Hospital Torino, starting from...