A5068477810- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Carbon Dioxide Capture Technologies
- Urinary and Genital Oncology Studies
- Cancer Immunotherapy and Biomarkers
- Reproductive tract infections research
- Reproductive System and Pregnancy
- Membrane Separation and Gas Transport
- Bladder and Urothelial Cancer Treatments
- Phase Equilibria and Thermodynamics
- Process Optimization and Integration
- Pregnancy and Medication Impact
- Zeolite Catalysis and Synthesis
- Industrial Gas Emission Control
Bristol-Myers Squibb (Switzerland)
2025
Bristol-Myers Squibb (United States)
2024
Politecnico di Milano
2021-2023
Institute of Social and Preventive Medicine
2016-2019
University of Bern
2016-2019
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary point, may be published when key planned co-primary or secondary analyses are not yet available. Trial Updates provide an opportunity to disseminate additional results from studies, in JCO elsewhere, for which point has already been reported . CheckMate 274 is a phase III, randomized, double-blind trial of adjuvant nivolumab versus placebo muscle-invasive...
Acid gas removal from gaseous streams such as flue gas, natural and biogas is mainly performed by chemical absorption with amines, but the process highly energy intensive can generate emissions of harmful compounds to atmosphere. Considering emerging interest in carbon capture, associated increasing environmental concerns, there much current effort develop innovative solvents able lower impact acid processes. To be competitive, new blends must show a CO2 uptake capacity comparable one...
HERCCULES is an Innovation Action under the Horizon Europe research programme aimed at demonstrating, for first time, feasibility of entire CCUS chain in southern TRL 7-8. The project focuses mainly on decarbonizing two strategic clusters northern Italy and Greece, specifically targeting hard-to-abate sectors: cement production energy from waste. To achieve this goal, significant effort being directed towards piloting demonstration activities. Three CO2 capture pilots are currently design...
The Horizon Europe HERCCULES project is an innovation action aimed at assessing the whole CCUS chain in southern Europe, focusing on cement and energy-from-waste sectors. A significant effort to achieve this ambitious goal dedicated demonstrating CO2 capture utilization technologies. Three technologies will be tested industry: amine-based solvent absorption system assess performance of a new generation using several configurations including innovative components; oxyfuel calciner coupled...
658 Background: In the phase 3, randomized, double-blind CheckMate 274 trial, adjuvant NIVO demonstrated statistically significant and clinically meaningful disease-free survival (DFS) benefit vs PBO in pts with high-risk MIUC after radical surgery (RS) ± prior neoadjuvant cisplatin-based chemotherapy (NAC). With extended 3-y median follow-up, continued improvements DFS were seen primary efficacy populations (intent-to-treat [ITT], tumor programmed death ligand 1 [PD-L1] expression ≥ 1%) MIBC....
Summary In order to accurately assess the burden of hepatitis C ( HCV ) and develop effective interventions, we must understand magnitude trends mortality related disease. United States, ‐related is continuously increasing. We have no comparable data for Switzerland other European countries, although a modelling study predicted similar increase. analysed time (1 January 1995‐31 December 2014) in ‐specific rates Swiss general population using death registry Federal Statistical Office SFSO )....
Hepatitis C virus (HCV) antigen testing is less expensive than quantitative reverse-transcription polymerase chain reaction but has lower sensitivity for very low viral load (VLVL; HCV RNA ≤3000 IU/mL). Currently the benefits of screening are discussed, data on prevalence and outcomes persons with VLVL scarce.We assessed predictors by logistic regression in treatment-naive participants Swiss Cohort Study. We analyzed if last after was low, compared cirrhosis mortality without VLVL, evaluated...
Background Switzerland recommends individuals who originate from high-prevalence countries to be screened for hepatitis C virus (HCV) infection. However, not all these persons are equally at risk. We thus aimed describe the number and characteristics of with HCV infection born outside Switzerland. Methods compared anti-HCV-positive in Swiss Hepatitis Cohort Study (SCCS) cases reported Federal Office Public Health (FOPH), those general population Persons inject drugs (PWID) do (non-PWID) were...
Summary Socio‐demographic and behavioural characteristics are associated with delayed diagnosis disease progression in HCV ‐infected persons. However, many analyses focused on single variables rather than groups defined by several variables. We used latent class analysis to study all 4488 persons enrolled the Swiss Hepatitis C Cohort Study. Groups were identified using predefined at enrolment. The number of was selected Bayesian information criterion. Mortality, loss follow‐up, cirrhosis,...
The growing attention regarding a more sustainable future, and thus into energy recovery waste reduction technologies, has intensified the interest towards processes which allow to exploit biomasses generate energy, such as anaerobic digestion. Improving efficiency of this industrial application is crucial increase methane production, essential from economic, environmental safety point view. This study focuses on thermodynamic modelling steady-state reactor flash unit, in order determine...
<h3>Background</h3> <i>Mycoplasma genitalium</i> causes urethritis in men and cervicitis women but characteristics of the infection have not been systematically reviewed. <h3>Objectives</h3> To determine incidence, persistence transmissibility <i>M. its role pelvic inflammatory disease (PID). <h3>Methods</h3> We searched Medline, EMBASE, LILACS, IndMed African Index Medicus. Two investigators selected studies extracted data independently. examined findings forest plots assessed heterogeneity...
<h3>Background</h3> <i>Mycoplasma genitalium</i> is a common cause of non-gonococcal non-chlamydial urethritis but prevalence rates in asymptomatic populations are not well-established. <h3>Objectives</h3> To estimate the <i>M. genitalium </i>in adult women and men general population clinic based samples. <h3>Methods</h3> We searched Embase, Medline, IndMED, AIM LILACS. examined eligible studies forest plots conducted random effects meta-analysis if appropriate. Between study heterogeneity...