- Veterinary Equine Medical Research
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Health and Disease Prevention
- Cardiovascular Conditions and Treatments
- Heart Rate Variability and Autonomic Control
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Hemodynamic Monitoring and Therapy
- Meat and Animal Product Quality
- Veterinary Pharmacology and Anesthesia
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Ischemia and Reperfusion
- Pharmacological Effects and Assays
- Sports Performance and Training
- Cardiac Imaging and Diagnostics
- Vascular anomalies and interventions
- Coronary Interventions and Diagnostics
- Non-Invasive Vital Sign Monitoring
- Spectroscopy Techniques in Biomedical and Chemical Research
- Central Venous Catheters and Hemodialysis
- Cardiovascular Syncope and Autonomic Disorders
Ghent University
2017-2025
Instituut voor Landbouw en Visserijonderzoek
2021
Atrial fibrillation (AF) is the most common pathological arrhythmia in horses. After successful treatment, recurrence common. Heart rate monitors are easily applicable horses and some devices offer basic heart variability (HRV) calculations. If HRV can be used to distinguish between AF sinus rhythm (SR), this could become a monitoring tool for at risk of AF.The purpose study was assess whether (before cardioversion) SR (after differentiated based upon parameters.Cohort with internal...
Ultra-high-density cardiac mapping allows very accurate characterisation of atrial and ventricular electrophysiology activation timing.To describe the technique evaluate feasibility magnetic electro-anatomical equine heart.In vivo experimental method development.A system using an 8.5F bidirectional deflectable catheter with a deployable mini-basket (3-22 mm) containing 64 electrodes divided over eight splines was evaluated. Based upon predefined beat acceptance criteria, automatically...
Heart rate variability (HRV) parameters, and especially RMSSD (root mean squared successive differences in RR interval), could distinguish atrial fibrillation (AF) from sinus rhythm(SR) horses, as was demonstrated a previous study. If heart monitors (HRM) automatically calculating also AF SR, they would be useful for the monitoring of recurrence. The objective study to assess whether values obtained HRM can differentiate SR horses. Furthermore, impact artifact correction algorithms,...
Summary Background Arrhythmias in horses may require long‐term anti‐arrhythmic therapy. Unfortunately, oral drugs for use are currently scarce. In human patients and small animals, sotalol, a β‐blocker with class III properties, is often used treatment. Objectives To determine the pharmacokinetics of sotalol at multiple dosages unfasted horses, as well effects on electro‐ echocardiographic measurements, right atrial ventricular monophasic action potential ( MAP ) effective refractory period...
Background Based on its pharmacokinetic profile and electrophysiological effects in healthy horses, sotalol potentially could be used as a long‐term PO antiarrhythmic drug horses. Objectives To evaluate the effect of heart rate (HR), QT interval, atrial fibrillatory rate, success cardioversion horses with naturally occurring chronic fibrillation (AF). Animals Twenty‐eight referred for transvenous electrical AF were treated 2 mg/kg q12h 3 days before cardioversion, 13 underwent same protocol...
Summary Background The number of atrial premature depolarisations (APDs) is a known risk factor for fibrillation (AF) recurrence in humans. Objectives To evaluate if the APDs over 24‐h period 5 days post cardioversion predicts AF within 1 year horses, taking multifactorial nature into account. Study design Retrospective case series. Methods Eighty horses met these inclusion criteria: first episode, no cardioversion, by transvenous electrical (TVEC), ECG recording and echocardiographic...
In human cardiology, the anatomical origin of atrial premature depolarizations (APDs) is derived from P wave characteristics on a 12-lead electrocardiogram (ECG) and vectorcardiography (VCG). The objective this study to differentiate between locations APDs sinus rhythm (SR) based upon VCG in seven horses without cardiovascular disease. A ECG was recorded under general anaesthesia while endomyocardial pacing performed (800–1000 ms cycle length) at left free wall septum, right wall,...
Abstract Background Echocardiographic reference intervals for Friesian horses are poorly described. Objectives To obtain echocardiographic measurements in Friesians and compare these with Warmbloods. Animals One hundred healthy adult 100 Warmblood horses. Methods Cross‐sectional study. Two‐dimensional M‐mode images were obtained. measurements, including size, area, volumetric of left atrium, right ventricle, aorta, pulmonary artery, performed. Measurements compared between the 2 breeds using...
Aortic regurgitation (AR) can have an important clinical impact and in some cases leads to left ventricular (LV) failure. Tissue Doppler imaging (TDI) is echocardiographic technique that has been used horses detect LV dysfunction.To examine whether TDI detects changes radial myocardial wall motion with AR compared control horses.Case-control study.Echocardiography was performed 30 healthy Warmblood 34 AR, subdivided groups mild, moderate or severe AR. measurements were on six segments of the...
In human cardiology, the anatomical origin of ventricular premature depolarizations (VPDs) is determined by characteristics a 12-lead electrocardiogram (ECG). Former studies in horses had contradictory results regarding diagnostic value ECG and vectorcardiography (VCG), which were attributed to different cardiac conduction system this species. The objective study was determine if pacing-induced VPDs could be differentiated based upon VCG characteristics. A recorded seven under general...
Atrial tachycardia including focal atrial and macroreentrant (atrial flutter), are occasionally found in horses. Diagnosis, treatment follow-up of these arrhythmias has been inadequately described.To describe the findings on surface electrocardiography (ECG), intra-atrial electrogram recording tissue Doppler imaging (TDI), response to by transvenous electrical cardioversion (TVEC), TDI follow-up, sustained horses.Case series.Records from horses with treated biphasic TVEC at Ghent University...
Abstract Background Aortic rupture is more common in Friesians compared to Warmbloods, which might be related differences arterial wall composition and, as such, stiffness (AWS). Currently, nothing known about AWS between these breeds. Objectives Comparison of parameters and noninvasive blood pressure Warmbloods. Animals One hundred one healthy 101 age‐matched Methods Two‐dimensional pulsed‐wave Doppler ultrasound examination was performed the aorta, carotid artery, external iliac artery...
Ventricular septal defects (VSDs) are the most common congenital cardiac defect in horses.
Abstract Rate‐adaptive single chamber pacemakers with accelerometer, closed loop stimulation (CLS), and remote monitoring functionality (Eluna 8 SR‐T, Biotronik, SE & Co, Germany) were implanted in 3 miniature donkeys third‐degree atrioventricular block syncope. After recovery, different pacemaker programming modes tested at rest, during stress without physical exercise exercise. Pacing rates compared to actual atrial showed that CLS allowed physiological heart rate adaptation. A...
In human and veterinary medicine, monophasic action potential (MAP) analysis determination of local refractory periods by contact electrode technique gives valuable information about cardiac electrophysiological properties. It is used to investigate dysrhythmias the impact drugs on myocardium. Precise measurement total MAP duration difficult, therefore usually determined at a repolarization level 90% (APD90). Until now, no studies are published feasibility this in standing non-sedated horse....
Arterial rupture in horses has been observed during exercise, after phenylephrine administration or parturition (uterine artery). In human pathophysiological research, the use of computer models for studying arterial hemodynamics and understanding normal abnormal characteristics pressure flow waveforms is very common. The objective this research was to develop a model equine circulation, order study local intra-arterial pressures dynamics horses. Morphologically, large differences exist...
Summary Background The use of commercial chromogenic agar plates for the rapid, easy and correct identification equine endometritis‐causing bacteria has been proposed. Preliminary tests in our lab revealed undescribed limitations. Therefore, we tested ability Brilliance UTI agar, a commercially available to accurately identify causing endometritis. Objectives To 1) investigate whether present uterus are able grow on this plate, 2) determine these belong genera which were originally designed...
Arterial rupture mainly affects older horses. The reason why horses are more prone to arterial and which underlying vascular changes predispose aortic is still unclear.To investigate the effect of ageing on equine wall blood pressure.Cohort study.Non-invasive pressure measurement using a tail cuff ultrasound from aorta, common carotid artery external iliac was performed in 50 healthy young (3-7 years) old Warmblood (>18 years). diameters cross-sectional areas, thickness were measured...
Een vierentwintig jaar oude merrie die zeven geleden onderzocht werd voor een mitralisklepregurgitatie en milde, linkszijdige cardiomegalie, aangeboden tachycardie, uitgesproken zweten spiertremor. Het bloedonderzoek toonde verhoogde hematocriet, metabole acidose, hypocalcemie, hyperglycemie cardiaal troponine I-concentratie aan. Elektrocardiografie talrijke ventriculaire premature contracties monomorfe tachycardie gevolgd door polymorfe met R-op-T fenomeen. Ondanks onmiddellijke behandeling...